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EVT-101

EVT-101, also known as ENS-101, is an experimental medication which originated from Roche and is under development by Evotec AG for the treatment of major depressive disorder. It acts as a selective NMDA receptor subunit 2B (NR2B) antagonist. The drug was first claimed by Roche in 2002. By 2017, EVT-101 was in phase II clinical trials for major…

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3D model (JSmol)
Interactive image
CAS Number
627525-33-1 1166398-51-1 1189088-41-2 (HClTooltip hydrochloride)
ChEMBL
ChEMBL3545350
ChemSpider
11255877
CompTox Dashboard (EPA)
DTXSID101127745
Drug class
NMDA receptor antagonist

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EVT-101

Nodes10
Edges9
Triples11
Avg. degree1.8
Density0.2
Components1

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EVT-101

Top relations

3D model (JSmol) · 1
EVT-101 → Interactive image
CAS Number · 1
EVT-101 → 627525-33-1 1166398-51-1 1189088-41-2 (HClTooltip hydrochloride)
ChEMBL · 1
EVT-101 → ChEMBL3545350
ChemSpider · 1
EVT-101 → 11255877
CompTox Dashboard (EPA) · 1
EVT-101 → DTXSID101127745
Drug class · 1
EVT-101 → NMDA receptor antagonist
Formula · 1
EVT-101 → C16H13F3N4
Molar mass · 1
EVT-101 → 318.303 g·mol−1
Other names · 1
EVT-101 → ENS-101
PubChem CID · 1
EVT-101 → 22240172

Important terminology Word statistics

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Important terminology

drug roche development major depressive disorder antagonist also ens-101 nmda receptor selective known experimental medication originated evotec ag treatment acts

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
EVT-1013D model (JSmol)Interactive image1.00infobox
EVT-101CAS Number627525-33-1 1166398-51-1 1189088-41-2 (HClTooltip hydrochloride)1.00infobox
EVT-101ChEMBLChEMBL35453501.00infobox
EVT-101ChemSpider112558771.00infobox
EVT-101CompTox Dashboard (EPA)DTXSID1011277451.00infobox
EVT-101Drug classNMDA receptor antagonist1.00infobox
EVT-101FormulaC16H13F3N41.00infobox
EVT-101Molar mass318.303 g·mol−11.00infobox
EVT-101Other namesENS-1011.00infobox
EVT-101PubChem CID222401721.00infobox
EVT-101UNII14DN1WB87S1.00infobox

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