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Peptidoglycan

Peptidoglycan, murein or mucopeptide is a unique large macromolecule, a polysaccharide, consisting of sugars and amino acids that forms a mesh-like layer (sacculus) that surrounds the bacterial cytoplasmic membrane. The sugar component consists of alternating residues of β-(1,4) linked N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM). Attached to…

Structure, Biosynthesis & Recognition by immune system

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Overview

Structure

Biosynthesis

Pseudopeptidoglycan

Recognition by immune system

As vaccine or adjuvant

Inhibition and degradation

Peptidoglycan as a danger signal among bacteria

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Map overview Semantic statistics

Peptidoglycan

Nodes185
Edges184
Triples103
Avg. degree1.99
Density0.010811
Components1

How this topic connects Entity context

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Peptidoglycan

Top relations

related to Biosynthesis · 30
Peptidoglycan → Also, Bactoprenol, C3, CoA, D-alanyl-D-alanine, EC, GlmM, GlmS, GlmU, In, MurA, MurB, MurC, MurD, MurE, MurNAc, N-acetyl-glucosamine-1-phosphate, N-acetyl-glucosamine-6-phosphate, NADPH, NAG
related to Structure · 19
Peptidoglycan → By, D-alanine, D-amino, D-glutamic, D-glutamine, Each MurNAc, Escherichia, GlcNAc, L-alanine, L-lysine, MurNAc, N-acetylglucosamine, N-acetylmuramic, NAG, NAM, Staphylococcus, The, This, When
related to Inhibition and degradation · 13
Peptidoglycan → C55-isoprenyl, DD-transpeptidases, For, II, L-form, Lantibiotics, Mutations, NAM-NAG, Other, Penicillin-binding, Since, Some, The
related to Peptidoglycan as a danger signal among bacteria · 10
Peptidoglycan → Acinetobacter, Enterococcus, Even, Exposure, II, In, Pseudomonas, Staphylococcus, The, Vibrio
related to External links · 7
Peptidoglycan → Bound Inhibitor, Diagrammatic, Haemophilus, MurNAc, MurQ, Phosphate Hydrolase, Structure
related to Pseudopeptidoglycan · 7
Peptidoglycan → In, Methanobacteriales, Methanopyrus, N-acetylglucosamine, N-acetyltalosaminuronic, The, This
related to Recognition by immune system · 7
Peptidoglycan → DAP, MDP, N-acetylglucosamine, NAG, Peptidoglycans, The, These
related to As vaccine or adjuvant · 3
Peptidoglycan → Freund's, MDP, Staphylococcus
related to Receptors · 2
Peptidoglycan → Innate, PRRs
is a · 1
Peptidoglycan → primary determinant of the characterisation of bacteria as gram-positive

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Important terminology

cell bacteria bacterial gram-positive also acid cells membrane amino murnac ec layer expressed wall gram-negative structure pglyrp-2 nod2 acids n-acetylglucosamine

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Peptidoglycanis aprimary determinant of the characterisation of bacteria as gram-positive0.90text
skininstance ofPGLYRP-3 and 4 are expressed by several tissues0.80text
sweat glandsinstance ofPGLYRP-3 and 4 are expressed by several tissues0.80text
eyes or the intestinal tractinstance ofPGLYRP-3 and 4 are expressed by several tissues0.80text
penicillin interfere with the production of peptidoglycan by binding to bacterial enzymes known as penicillin-binding proteins or DD-transpeptidasesinstance ofInhibition and degradationSome antibacterial drugs0.80text
Peptidoglycanrelated to As vaccine or adjuvantMDP0.60section
Peptidoglycanrelated to As vaccine or adjuvantFreund's0.60section
Peptidoglycanrelated to As vaccine or adjuvantStaphylococcus0.60section
Peptidoglycanrelated to BiosynthesisThe0.60section
Peptidoglycanrelated to BiosynthesisBactoprenol0.60section
Peptidoglycanrelated to BiosynthesisIn0.60section
Peptidoglycanrelated to BiosynthesisThis0.60section

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