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Antibody

An antibody (Ab), or immunoglobulin (Ig), is a large protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens such as those that exist on bacteria and virus cells, including those that cause disease. Each individual antibody recognizes one or more specific antigens, and antigens (a…

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Overview

Sources of antibodies

Structure

Classes

Antibody–antigen interactions

Function

Immunoglobulin diversity

History

Medical applications

Research applications

Regulations

Structure prediction and computational antibody design

Antibody mimetic

Binding antibody unit

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Map overview Semantic statistics

Antibody

Nodes343
Edges342
Triples334
Avg. degree1.99
Density0.005831
Components1

How this topic connects Entity context

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Antibody

Top relations

related to history · 23
Antibody → Almroth Wright, Amboceptor, Antikörper, As, Behring, Desmon, Emil, English, Experimental Studies, German, His, However, Immunisin, Immunity, Immunkörper, Kitasato, Kitasato Shibasaburō, October, Other, Paul Ehrlich
related to Class switching · 18
Antibody → Class, CSR, DNA, Each, IgA, IgD, IgE, IgG, IgM, Initially, Isotype, NHEJ, Only, S-regions, The, The DNA, This, Thus
has application · 17
Antibody → Antibodies, Antigens, Blood, ELISA, ELISpot, For, In, Polyclonal, Protein A/G, Proteins, Research, Single, Specific, The, They, To, Western
related to Structure prediction and computational antibody design · 17
Antibody → CDR, CDRs, Computational, FV, However, Immunoglobulin Structure, Online, PIGS, Prediction, Rosetta Antibody, Several, The, This, To, WAM, Web Antibody Modeling, X-ray
related to Domain variability · 15
Antibody → CDR1, CDR2, CDR3, CDRs, Combining, Differences, HV-1, HV-2, HV-3, IGH, IGK, IGL, One, The, This
related to Sources of antibodies · 15
Antibody → Antibodies, BLIMP-1, Classically, However, IgA, IgE, IgG-secreting, IgM, In, It, Long-lived, Occasionally, Plasma, Plasmablasts, The
related to Fc region · 14
Antibody → Another, C1q, Effector, Fab, Fc, FcR, FcRn, IgA, IgG, IgG3, IgM, In, Its, The Fc
related to Classes · 13
Antibody → Antibodies, Fc, For, Ig, IgA, IgA1, IgA2, IgD, IgE, IgG, IgM, In, The
related to Antibody complexes · 12
Antibody → An, Antibodies, However, Ig, IgA, IgG, IgM, IgW, Multivalent, Secreted, Small, Y-shaped
related to B cell receptors · 12
Antibody → BCR, BCRs, Ig-α, Ig-β, IgD, IgM, In, It, The, The BCR, These, Upon

Important terminology Word statistics

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Important terminology

antibodies cells antigen cell immune different also antigens region immunoglobulin chain heavy igg affinity form system binding variable proteins light

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Antibodyis abody directed against something.The study of antibodies began in 1890 when Emil von Behring and Kitasato Shibasaburō described antibody activity against diphtheria and tetanus t…0.90text
Antibodyis anovel antibody FV region structure prediction server0.90text
those that exist on bacteriainstance ofis a large protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens0.80text
virus cellsinstance ofis a large protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens0.80text
including those that cause diseaseinstance ofis a large protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens0.80text
toll-like receptor ligandsinstance ofby the presence of adjuvant molecules that stimulate the immune response0.80text
polysaccharides in bacterial cell wallsinstance ofrepeating sites0.80text
or other sites at some distance apartinstance ofrepeating sites0.80text
IgA1instance ofwhich are further subdivided into subclasses0.80text
IgA2instance ofwhich are further subdivided into subclasses0.80text
the complement pathwayinstance ofand they trigger destruction of pathogens by stimulating other immune responses0.80text
serology depend on these methodsinstance ofand applications0.80text

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