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Classical complement pathway

The classical complement pathway is one of three pathways which activate the complement system, which is part of the immune system. The classical complement pathway is initiated by antigen-antibody complexes with the antibody isotypes IgG and IgM.

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Overview

Complement cascade

Clinical significance

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Map overview Semantic statistics

Classical complement pathway

Nodes34
Edges33
Triples18
Avg. degree1.94
Density0.058824
Components1

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Classical complement pathway

Top relations

related to Initiation · 10
Classical complement pathway → C1, C1q, C1r, C1s, Fc, IgG, IgM, In, The, These
related to Clinical significance · 8
Classical complement pathway → Because, C1, Complement, HIV, IgG, Immunotherapies, Obesity, This

Important terminology Word statistics

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Important terminology

complement classical pathway c1q activation convertase cells complex c3b c4b c5 immune also c3 cleaves protein cleaved target proteins c1s

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Classical complement pathwayrelated to Clinical significanceBecause0.60section
Classical complement pathwayrelated to Clinical significanceComplement0.60section
Classical complement pathwayrelated to Clinical significanceObesity0.60section
Classical complement pathwayrelated to Clinical significanceC10.60section
Classical complement pathwayrelated to Clinical significanceImmunotherapies0.60section
Classical complement pathwayrelated to Clinical significanceHIV0.60section
Classical complement pathwayrelated to Clinical significanceThis0.60section
Classical complement pathwayrelated to Clinical significanceIgG0.60section
Classical complement pathwayrelated to InitiationThe0.60section
Classical complement pathwayrelated to InitiationC1q0.60section
Classical complement pathwayrelated to InitiationFc0.60section
Classical complement pathwayrelated to InitiationIgG0.60section

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