Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Fibroblast growth factor 2: Function, Interactions & Overview

Fibroblast growth factor 2 (FGF-2), also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by the FGF2 gene. It binds to and exerts effects via specific fibroblast growth factor receptor (FGFR) proteins, themselves a family of closely related molecules. Fibroblast growth factor protein was first…

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Fibroblast growth factor 2 topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around Fibroblast growth factor 2.

Related topics
52
Source areas
3
Connected nodes
55
Extracted relationships
139
Concept neighborhoods
22
Bridge connections
55

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 42 topics
Interactions · 5 topics
Overview · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
FGF2, BFGF, FGF-2, FGFB, HBGF-2, fibroblast growth factor 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BAS, 1BFB, 1BFC, 1BFF, 1BFG, 1BLA, 1BLD, 1CVS, 1EV2, 1FGA, 1FQ9, 1II4, 1IIL, 2BFH, 2FGF, 2M49, 4FGF, 4OEE,…
Band
4q28.1 · 3 B|3 18.41 cM
Bgee
cartilage tissue · Epithelium of choroid plexus · Achilles tendon · smooth muscle tissue · stromal cell of endometrium
BioGPS
More reference expression data
Chr.
Chromosome 4 (human) · Chromosome 3 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Fibroblast growth factor 2 connects Entity context

The extracted context around Fibroblast growth factor 2 shows recurring relationship patterns in the source. For example, Fibroblast growth factor 2 → 1-phosphatidylinositol-3-kinase activity, angiogenesis, animal organ morphogenesis, branching involved in ureteric bud morphogenesis, cell differentiation, cell migration involved in sprouting angiogenesis, chemoattractant activity, chemotaxis, chondroblast differentiation, cytokine activity, cytokine-mediated signaling pathway, embryonic morphogenesis, extracellular matrix organization, extracellular region, extracellular space, fibroblast growth factor receptor binding, fibroblast growth factor receptor signaling pathway, growth factor activity, growth factor dependent regulation of skeletal muscle satellite cell proliferation, heparin binding Another extracted example is Fibroblast growth factor 2 → Achilles tendon, adipose tissue, ankle, aortic valve, ascending aorta, carotid body, cartilage tissue, decidua, Descending thoracic aorta, efferent ductule, epididymis, Epithelium of choroid plexus, esophagus, gastrula, muscle layer of sigmoid colon, retinal pigment epithelium, smooth muscle tissue, stromal cell of endometrium, subcutaneous adipose tissue, vas deferens. Use these groups to spot repeated connection types before inspecting the individual relationships.

Fibroblast growth factor 2

Top relations

Gene ontology · 72
Fibroblast growth factor 2 → 1-phosphatidylinositol-3-kinase activity, angiogenesis, animal organ morphogenesis, branching involved in ureteric bud morphogenesis, cell differentiation, cell migration involved in sprouting angiogenesis, chemoattractant activity, chemotaxis, chondroblast differentiation, cytokine activity, cytokine-mediated signaling pathway, embryonic morphogenesis, extracellular matrix organization, extracellular region, extracellular space, fibroblast growth factor receptor binding, fibroblast growth factor receptor signaling pathway, growth factor activity, growth factor dependent regulation of skeletal muscle satellite cell proliferation, heparin binding
Bgee · 20
Fibroblast growth factor 2 → Achilles tendon, adipose tissue, ankle, aortic valve, ascending aorta, carotid body, cartilage tissue, decidua, Descending thoracic aorta, efferent ductule, epididymis, Epithelium of choroid plexus, esophagus, gastrula, muscle layer of sigmoid colon, retinal pigment epithelium, smooth muscle tissue, stromal cell of endometrium, subcutaneous adipose tissue, vas deferens
RNA expression pattern · 20
Fibroblast growth factor 2 → Achilles tendon, adipose tissue, ankle, aortic valve, ascending aorta, carotid body, cartilage tissue, decidua, Descending thoracic aorta, efferent ductule, epididymis, Epithelium of choroid plexus, esophagus, gastrula, muscle layer of sigmoid colon, retinal pigment epithelium, smooth muscle tissue, stromal cell of endometrium, subcutaneous adipose tissue, vas deferens
related to Interactions · 4
Fibroblast growth factor 2 → API5, Fibroblast, RPL6, S19
Band · 2
Fibroblast growth factor 2 → 3 B|3 18.41 cM, 4q28.1
Chr. · 2
Fibroblast growth factor 2 → Chromosome 3 (mouse), Chromosome 4 (human)
End · 2
Fibroblast growth factor 2 → 122,898,236 bp, 37,464,257 bp
Aliases · 1
Fibroblast growth factor 2 → FGF2, BFGF, FGF-2, FGFB, HBGF-2, fibroblast growth factor 2
Available structures · 1
Fibroblast growth factor 2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BAS, 1BFB, 1BFC, 1BFF, 1BFG, 1BLA, 1BLD, 1CVS, 1EV2, 1FGA, 1FQ9, 1II4, 1IIL, 2BFH, 2FGF, 2M49, 4FGF, 4OEE,…
BioGPS · 1
Fibroblast growth factor 2 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

fgf2 growth factor fibroblast cell protein human gene bp differentiation fgf-2 chr band development bfgf receptor proteins chromosome also location

Fibroblast growth factor 2 relationships Subject–Predicate–Object triples

TTTA extracted 139 structured relationships around Fibroblast growth factor 2. Examples in this analysis include Fibroblast growth factor 2 → Aliases → FGF2, BFGF, FGF-2, FGFB, HBGF-2, fibroblast growth factor 2 and Fibroblast growth factor 2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BAS, 1BFB, 1BFC, 1BFF, 1BFG, 1BLA, 1BLD, 1CVS, 1EV2, 1FGA, 1FQ9, 1II4, 1IIL, 2BFH, 2FGF, 2M49, 4FGF, 4OEE,…. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Fibroblast growth factor 2AliasesFGF2, BFGF, FGF-2, FGFB, HBGF-2, fibroblast growth factor 21.00infobox
Fibroblast growth factor 2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BAS, 1BFB, 1BFC, 1BFF, 1BFG, 1BLA, 1BLD, 1CVS, 1EV2, 1FGA, 1FQ9, 1II4, 1IIL, 2BFH, 2FGF, 2M49, 4FGF, 4OEE,…1.00infobox
Fibroblast growth factor 2Band4q28.11.00infobox
Fibroblast growth factor 2Band3 B|3 18.41 cM1.00infobox
Fibroblast growth factor 2Bgeecartilage tissue1.00infobox
Fibroblast growth factor 2BgeeEpithelium of choroid plexus1.00infobox
Fibroblast growth factor 2BgeeAchilles tendon1.00infobox
Fibroblast growth factor 2Bgeesmooth muscle tissue1.00infobox
Fibroblast growth factor 2Bgeestromal cell of endometrium1.00infobox
Fibroblast growth factor 2BgeeDescending thoracic aorta1.00infobox
Fibroblast growth factor 2Bgeeadipose tissue1.00infobox
Fibroblast growth factor 2Bgeeretinal pigment epithelium1.00infobox
Fibroblast growth factor 2Bgeesubcutaneous adipose tissue1.00infobox
Fibroblast growth factor 2Bgeemuscle layer of sigmoid colon1.00infobox
Fibroblast growth factor 2Bgeeascending aorta1.00infobox
Fibroblast growth factor 2Bgeeaortic valve1.00infobox
Fibroblast growth factor 2Bgeevas deferens1.00infobox
Fibroblast growth factor 2Bgeeefferent ductule1.00infobox
Fibroblast growth factor 2Bgeeankle1.00infobox
Fibroblast growth factor 2Bgeedecidua1.00infobox
Fibroblast growth factor 2Bgeegastrula1.00infobox
Fibroblast growth factor 2Bgeeepididymis1.00infobox
Fibroblast growth factor 2Bgeecarotid body1.00infobox
Fibroblast growth factor 2Bgeeesophagus1.00infobox
Fibroblast growth factor 2BioGPSMore reference expression data1.00infobox
Fibroblast growth factor 2Chr.Chromosome 4 (human)1.00infobox
Fibroblast growth factor 2Chr.Chromosome 3 (mouse)1.00infobox
Fibroblast growth factor 2DatabasesNCBI: entry; OMA: entry1.00infobox
Fibroblast growth factor 2End122,898,236 bp1.00infobox
Fibroblast growth factor 2End37,464,257 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Fibroblast growth factor 2 bring nearby vocabulary together. In this analysis, examples include Factor, Fibroblast and Growth. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Fibroblast growth factor 2
    • Factor
    • Fibroblast
    • Growth
    • Receptor
    • Basic
    • Protein
    • Also
    • Gene
    • Angiogenesis
    • Family
    • Kinase
    • Proliferation
  • fibroblast growth factor 2
    • Growth
    • Factor
    • Fibroblast
    • Receptor
    • Basic
    • Protein
    • Also
    • Cell
    • Gene
    • Fgf-2
    • Human
    • Angiogenesis
  • growth factor
    • Growth
    • Fibroblast
    • Receptor
    • Basic
    • Protein
    • Also
    • Cell
    • Fgf-2
    • Gene
    • Human
    • Angiogenesis
    • Embryonic
  • signaling protein
    • Signaling
    • Family
    • Fgf
    • Kinase
    • Signal
    • Tissue
    • Stem
    • Cell
    • Mouse
    • Angiogenesis
    • Embryonic
    • Expression
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Mouse
    • Protein
    • Family
    • Fgf
    • Signaling
    • Band
    • Function
  • fibroblast growth factor receptor
    • Growth
    • Factor
    • Fibroblast
    • Receptor
    • Basic
    • Protein
    • Also
    • Proliferation
    • Signal
    • Cell
    • Gene
    • Fgf-2
  • family of fgf
    • Embryonic
    • Expression
    • Fgf
    • Kinase
    • Proteins
    • Development
    • Receptor
    • Differentiation
    • Gene
    • Mouse
    • Protein
    • Fibroblast
  • embryonic development
    • Expression
    • Fgf
    • Kinase
    • Stem
    • Embryonic
    • Receptor
    • Human
    • Mouse
    • Differentiation
    • Fgf2
    • Factor
    • Family

Connections between topic areas Semantic bridges

For Fibroblast growth factor 2, one of the stronger structural bridges in this analysis connects Fibroblast growth factor 2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Fibroblast growth factor 2Function · splits 13 ⟂ 43
Fibroblast growth factor 2Overview · splits 50 ⟂ 6
Fibroblast growth factor 2Interactions · splits 50 ⟂ 6

Map overview Semantic statistics

Fibroblast growth factor 2

Nodes56
Edges55
Triples139
Avg. degree1.96
Density0.035714
Components1

Source & methodology

TTTA analyzes the structure around Fibroblast growth factor 2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Fibroblast growth factor 2 · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.