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Factor XIII, or fibrin stabilizing factor, is a plasma protein and zymogen. It is activated by thrombin to factor XIIIa which crosslinks fibrin in coagulation. Deficiency of XIII worsens clot stability and increases bleeding tendency.
The analysis highlights Applications and Measurement as prominent areas in the source structure around Factor XIII.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Factor XIII shows recurring relationship patterns in the source. For example, Factor XIII → Both, Ca2, G38, In, N-terminal, R37, Within, XIII Another extracted example is Factor XIII → C-terminal, Dimers, Large, N-terminal, Non-covalently, These, XIII, XIIIa. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
xiii factor units xiiia blood peptides clot deficiency fibrin kbp coagulation within human domains activated also dimer two crosslinks heterotetramer
TTTA extracted 53 structured relationships around Factor XIII. Examples in this analysis include Factor XIII → Alt. symbols → F13A and Factor XIII → Domains → InterPro. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Factor XIII | Alt. symbols | F13A | 1.00 | infobox |
| Factor XIII | Domains | InterPro | 1.00 | infobox |
| Factor XIII | EC number | 2.3.2.13 | 1.00 | infobox |
| Factor XIII | HGNC | 3531 | 1.00 | infobox |
| Factor XIII | Locus | Chr. 6 p24.2-p23 | 1.00 | infobox |
| Factor XIII | NCBI gene | 2162 | 1.00 | infobox |
| Factor XIII | OMIM | 134570 | 1.00 | infobox |
| Factor XIII | RefSeq | NM_000129 | 1.00 | infobox |
| Factor XIII | Search for | Search forStructuresSwiss-modelDomainsInterPro | 1.00 | infobox |
| Factor XIII | Structures | Swiss-model | 1.00 | infobox |
| Factor XIII | Symbol | F13A1 | 1.00 | infobox |
| Factor XIII | UniProt | P00488 | 1.00 | infobox |
| Factor XIII | is a | transglutaminase that circulates in human blood as a heterotetramer of two A and two B subunits | 0.90 | text |
The concept neighborhoods around Factor XIII bring nearby vocabulary together. In this analysis, examples include Xiii, Deficiency and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Factor XIII, one of the stronger structural bridges in this analysis connects Factor XIII with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Factor XIII to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications & Measurement, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Factor XIII · EN edition · Analysis: TopicsToTalkAbout