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Enobosarm: History, Community, Culture & Research

Enobosarm, also formerly known as ostarine and by the developmental code names GTx-024, MK-2866, and S-22, is a selective androgen receptor modulator (SARM) which is under development for the treatment of androgen receptor-positive breast cancer in women and for improvement of body composition (e.g., prevention of muscle loss) in people taking GLP-1…

Language: English [EN]
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Enobosarm topic overview

The analysis highlights History, Community, Culture and Research as prominent areas in the source structure around Enobosarm.

Related topics
291
Source areas
9
Connected nodes
300
Extracted relationships
128
Related term clusters
56
Bridge connections
300

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 134 topics
Side effects · 57 topics
Pharmacology · 52 topics
History · 18 topics
Society and culture · 12 topics
Chemistry · 10 topics
Interactions · 5 topics
Research · 2 topics
Overdose · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
ATC code
None
Bioavailability
100% (rats)
CAS Number
841205-47-8
ChEMBL
ChEMBL1738889
ChemSpider
9501667

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Side effects

Overdose

Interactions

Pharmacology

Chemistry

History

Society and culture

Research

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Enobosarm connects Entity context

The extracted context around Enobosarm shows recurring relationship patterns in the source. For example, Enobosarm → AR, Co, Dalton, Europe, GTx, GTx-007, GTx-024, GTx-758, In August, James, Memphis, Merck, S-22, S-4, SARM, SARM-type, SARMs, SERM, Tennessee, Tennessee Research Foundation Another extracted example is Enobosarm → Aside, Doses, GTx-007, Internet, LGD-4033, London, Many, MDMA, Netherlands, RAD140, S-4, SARMs, Social, VK5211. Use these groups to spot repeated connection types before inspecting the individual relationships.

Enobosarm

Top relations

related to history · 21
Enobosarm → AR, Co, Dalton, Europe, GTx, GTx-007, GTx-024, GTx-758, In August, James, Memphis, Merck, S-22, S-4, SARM, SARM-type, SARMs, SERM, Tennessee, Tennessee Research Foundation
related to Non-medical use · 14
Enobosarm → Aside, Doses, GTx-007, Internet, LGD-4033, London, Many, MDMA, Netherlands, RAD140, S-4, SARMs, Social, VK5211
related to Pharmacodynamics · 14
Enobosarm → Although, Another, AR, AR-expressing, DHT, Induction, Ki, LGD-2226, MCF-7, MDA-MB-231, N/C, SARM, SARMs, The AR
related to Interactions · 11
Enobosarm → Based, BCRP, CYP2C9, CYP3A4, P450, P50, Since, UDP-glucuronosyltransferase, UGT, UGT1A1, UGT2B7
related to Names · 11
Enobosarm → GTx, GTx-024, Inc, INN, International Nonproprietary Name, Merck, MK-2866, Ostarine, S-22, Veru, VERU-024
has effect · 10
Enobosarm → Decreases, Despite, DHT, FSH, General, HDL, LDL, LH, SHBG, Small
related to Chemistry · 8
Enobosarm → Bicalutamide, GTx-007, GTx-027, S-1, S-4, SARM S-1, SARM-like, SARMs
related to Overdose · 4
Enobosarm → ARTEST, Doses, Internet, Larger
is a · 3
Enobosarm → nonsteroidal SARM, substrate of CYP3A4 and UGT enzymes.The metabolism of enobosarm is similar to that of the closely structurally related drug bicalutamide, substrate of CYP3A4 and UGT enzymes.The metabolism of enobosarm is similar to that of the closely structurally related drug bicalutamide.EliminationIn rats
related to Doping in sport · 3
Enobosarm → January, SARMs, World Anti-Doping Agency

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

effects muscle clinical trials doses mg like testosterone sarms day drug phase development also levels anabolic cancer prostate may women

Enobosarm relationships Subject–Predicate–Object triples

TTTA extracted 128 structured relationships around Enobosarm. Examples in this analysis include Enobosarm → 3D model (JSmol) → Interactive image and Enobosarm → ATC code → None. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Enobosarm3D model (JSmol)Interactive image1.00infobox
EnobosarmATC codeNone1.00infobox
EnobosarmBioavailability100% (rats)1.00infobox
EnobosarmCAS Number841205-47-81.00infobox
EnobosarmChEMBLChEMBL17388891.00infobox
EnobosarmChemSpider95016671.00infobox
EnobosarmCompTox Dashboard (EPA)DTXSID302330061.00infobox
EnobosarmDrugBankDB12078 Y1.00infobox
EnobosarmElimination half-life14–24 hours1.00infobox
EnobosarmExcretionFeces (70%), urine (21–25%) (rats)1.00infobox
EnobosarmFormulaC19H14F3N3O31.00infobox
EnobosarmKEGGD102211.00infobox
EnobosarmLegal statusUS: Investigational New Drug1.00infobox
EnobosarmMelting point132 to 136 °C (270 to 277 °F)1.00infobox
EnobosarmMetabolismCYP3A4, UGT1A1, UGT2B71.00infobox
EnobosarmMetabolitesEnobosarm glucuronide1.00infobox
EnobosarmMolar mass389.334 g·mol−11.00infobox
EnobosarmOther namesOstarine; GTx-024; MK-2866; S-22; VERU-0241.00infobox
EnobosarmPDB ligandRLJ (PDBe, RCSB PDB)1.00infobox
EnobosarmPubChem CID113267151.00infobox
EnobosarmRoutes of administrationBy mouth1.00infobox
EnobosarmUNIIO3571H3R8N1.00infobox
Enobosarmis anonsteroidal SARM0.90text
Enobosarmis asubstrate of CYP3A4 and UGT enzymes.The metabolism of enobosarm is similar to that of the closely structurally related drug bicalutamide.EliminationIn rats0.90text
Enobosarmis asubstrate of CYP3A4 and UGT enzymes.The metabolism of enobosarm is similar to that of the closely structurally related drug bicalutamide0.90text

Related concept clusters Related term clusters

The concept neighborhoods around Enobosarm bring nearby vocabulary together. In this analysis, examples include Effects, Clinical and Trials. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Enobosarm
    • Effects
    • Clinical
    • Trials
    • Mg
    • Muscle
    • Doses
    • Day
    • Phase
    • Like
    • Cancer
    • Women
    • Drug
  • enobosarm
    • Effects
    • Clinical
    • Trials
    • Mg
    • Muscle
    • Doses
    • Day
    • Phase
    • Like
    • Cancer
    • Women
    • Drug
  • breast cancer
    • Cancer
    • Treatment
    • Phase
    • Trials
    • Body
    • Clinical
    • Muscle
    • Development
    • Mass
    • Day
    • Bone
    • Women
  • body composition
    • Mass
    • Women
    • Muscle
    • Cancer
    • Clinical
    • Trials
    • Like
    • Treatment
    • Phase
    • Agonists
    • Breast
    • Mg
  • cancer
    • Treatment
    • Phase
    • Trials
    • Body
    • Clinical
    • Muscle
    • Mass
    • Day
    • Development
    • Women
    • Mg
    • Enobosarm
  • lean body mass
    • Mass
    • Women
    • Muscle
    • Cancer
    • Clinical
    • Trials
    • Like
    • Treatment
    • Phase
    • Agonists
    • Breast
    • Mg
  • body hair
    • Mass
    • Women
    • Muscle
    • Cancer
    • Clinical
    • Trials
    • Like
    • Treatment
    • Phase
    • Agonists
    • Breast
    • Mg
  • non-small-cell lung cancer
    • Treatment
    • Phase
    • Trials
    • Body
    • Clinical
    • Muscle
    • Mass
    • Day
    • Development
    • Women
    • Mg
    • Enobosarm

Connections between topic areas Semantic bridges

For Enobosarm, one of the stronger structural bridges in this analysis connects Enobosarm with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Enobosarm — Overview · splits 166 ⟂ 135
Enobosarm — Side effects · splits 243 ⟂ 58
Enobosarm — Pharmacology · splits 248 ⟂ 53
Enobosarm — History · splits 282 ⟂ 19
Enobosarm — Society and culture · splits 288 ⟂ 13
Enobosarm — Chemistry · splits 290 ⟂ 11
Enobosarm — Interactions · splits 295 ⟂ 6
Enobosarm — Research · splits 298 ⟂ 3

Map overview Semantic statistics

Enobosarm

Nodes301
Edges300
Triples128
Avg. degree1.99
Density0.006645
Components1

Source & methodology

TTTA analyzes the structure around Enobosarm to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Enobosarm · EN edition · Analysis: TopicsToTalkAbout

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