Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Celecoxib: History, Community, Culture & Applications

Celecoxib, sold under the brand name Celebrex among others, is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. It may also be…

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Celecoxib topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Celecoxib.

Related topics
98
Source areas
7
Connected nodes
105
Extracted relationships
168
Concept neighborhoods
26
Bridge connections
105

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 30 topics
Adverse effects · 25 topics
History · 16 topics
Research · 10 topics
Society and culture · 7 topics
Mechanism of action · 6 topics
Medical uses · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
L01XX33 (WHO) M01AH01 (WHO)
Bioavailability
Unknown
CAS Number
169590-42-5 Y
ChEBI
CHEBI:41423 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Mechanism of action

History

Society and culture

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Celecoxib connects Entity context

The extracted context around Celecoxib shows recurring relationship patterns in the source. For example, Celecoxib → April, Brigham Young University, BYU, Cir, Co, COX-2, Daniel, Fed, It, John Talley, Monsanto, Monsanto's, Other, Pfizer, Rochester, Searle, Simmons, The, Two, University Another extracted example is Celecoxib → Anemia, Cardiovascular, Gastrointestinal, GI, Hematologic, Individual, Long-term, Moderate, New-onset, NSAIDs, People, Risk, The, These, Use, When. Use these groups to spot repeated connection types before inspecting the individual relationships.

Celecoxib

Top relations

related to history · 21
Celecoxib → April, Brigham Young University, BYU, Cir, Co, COX-2, Daniel, Fed, It, John Talley, Monsanto, Monsanto's, Other, Pfizer, Rochester, Searle, Simmons, The, Two, University
has effect · 16
Celecoxib → Anemia, Cardiovascular, Gastrointestinal, GI, Hematologic, Individual, Long-term, Moderate, New-onset, NSAIDs, People, Risk, The, These, Use, When
related to External links · 14
Celecoxib → Archived, Bextra, Celebrex, COX-2 Selective, Drug Administration, FDA, FDA Approves Labeling Supplement, Food, July, June, Non-Selective Non-Steroidal Anti-Inflammatory Drugs, NSAIDs, September, Vioxx
related to Brand names · 12
Celecoxib → Celebrex, December, FDA, In, It, March, May, On, Pfizer, Upon, US, US RE44048
related to Heart attack and stroke · 12
Celecoxib → American Heart Association, As, COX-2, FDA, FDA-mandated, In, In February, Like, NSAIDs, The COX-2, US, Vioxx
related to Structure-activity relationship · 12
Celecoxib → At, COX-1, COX-2, For, Ile523, In, SO2NHCH3, The, The Searle, This, To, Various
related to Anti-inflammatory · 9
Celecoxib → A2, COX-1, COX-2, In, Inhibition, It, Nonselective NSAIDs, NSAIDs, Therefore
related to Drug interactions · 9
Celecoxib → Additionally, Caution, CYP2C9, CYP2D6, CYP3A4, If, SSRI, The, The CYP2C9
has treatment · 8
Celecoxib → Certainly, COX-2, Different, For, However, Karen Seibert, Many, The
Legal status · 7
Celecoxib → AU: S4 (Prescription only) or S3, BR: Class C1 (Other controlled substances), CA: ℞-only, In general: ℞ (Prescription only), NZ: Prescription only, UK: POM (Prescription only), US: ℞-only

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cox-2 risk pfizer drug may use nsaids effects celebrex people searle pain drugs cardiovascular used fda inhibition treatment anti-inflammatory cancer

Celecoxib relationships Subject–Predicate–Object triples

TTTA extracted 168 structured relationships around Celecoxib. Examples in this analysis include Celecoxib → 3D model (JSmol) → Interactive image and Celecoxib → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Celecoxib3D model (JSmol)Interactive image1.00infobox
CelecoxibAHFS/Drugs.comMonograph1.00infobox
CelecoxibATC codeL01XX33 (WHO) M01AH01 (WHO)1.00infobox
CelecoxibBioavailabilityUnknown1.00infobox
CelecoxibCAS Number169590-42-5 Y1.00infobox
CelecoxibChEBICHEBI:41423 Y1.00infobox
CelecoxibChEMBLChEMBL118 Y1.00infobox
CelecoxibChemSpider2562 Y1.00infobox
CelecoxibCompTox Dashboard (EPA)DTXSID00227771.00infobox
CelecoxibDrug classCyclooxygenase-2 (COX-2) inhibitor1.00infobox
CelecoxibDrugBankDB00482 Y1.00infobox
CelecoxibECHA InfoCard100.211.6441.00infobox
CelecoxibElimination half-life7.8 hours; 11 hours (mild hepatic impairment); 13 hours (moderate-severe hepatic impairment)1.00infobox
CelecoxibExcretionFaeces (57%), urine (27%)1.00infobox
CelecoxibFormulaC17H14F3N3O2S1.00infobox
CelecoxibIUPHAR/BPS28921.00infobox
CelecoxibKEGGD00567 Y1.00infobox
CelecoxibLegal statusAU: S4 (Prescription only) or S31.00infobox
CelecoxibLegal statusBR: Class C1 (Other controlled substances)1.00infobox
CelecoxibLegal statusCA: ℞-only1.00infobox
CelecoxibLegal statusNZ: Prescription only1.00infobox
CelecoxibLegal statusUK: POM (Prescription only)1.00infobox
CelecoxibLegal statusUS: ℞-only1.00infobox
CelecoxibLegal statusIn general: ℞ (Prescription only)1.00infobox
CelecoxibLicense dataUS DailyMed: Celecoxib1.00infobox
CelecoxibMedlinePlusa6990221.00infobox
CelecoxibMetabolismLiver (mainly CYP2C9)1.00infobox
CelecoxibMolar mass381.37 g·mol−11.00infobox
CelecoxibPDB ligandCEL (PDBe, RCSB PDB)1.00infobox
CelecoxibPregnancy categoryAU: B31.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Celecoxib bring nearby vocabulary together. In this analysis, examples include Cox-2, Selective and Inhibition. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Celecoxib
    • Cox-2
    • Selective
    • Inhibition
    • Drug
    • Use
    • May
    • Anti-inflammatory
    • Inhibitors
    • Treatment
    • Risk
    • Drugs
    • Also
  • celecoxib
    • Cox-2
    • Selective
    • Inhibition
    • Drug
    • Use
    • May
    • Anti-inflammatory
    • Inhibitors
    • Treatment
    • Risk
    • Drugs
    • Also
  • cox-2 inhibitor
    • Inhibition
    • Inhibit
    • Selective
    • Effects
    • Drug
    • Searle
    • Cox-1
    • Found
    • Inhibitors
    • Studies
    • Pain
    • Drugs
  • nonsteroidal anti-inflammatory drug
    • Administration
    • Celebrex
    • Pain
    • Drug
    • Fda
    • Drugs
    • Reduce
    • Research
    • Studies
    • Cox-2
    • Risk
    • Effects
  • pain
    • Drug
    • Administration
    • Studies
    • Treatment
    • Inflammation
    • Effects
    • Heart
    • Reduce
    • Research
    • Found
    • Inhibitors
    • Drugs
  • acute pain
    • Drug
    • Administration
    • Studies
    • Treatment
    • Inflammation
    • Effects
    • Heart
    • Reduce
    • Research
    • Found
    • Inhibitors
    • Drugs
  • abdominal pain
    • Drug
    • Administration
    • Studies
    • Treatment
    • Inflammation
    • Effects
    • Heart
    • Reduce
    • Research
    • Found
    • Inhibitors
    • Drugs
  • musculoskeletal pain
    • Drug
    • Administration
    • Studies
    • Treatment
    • Inflammation
    • Effects
    • Heart
    • Reduce
    • Research
    • Found
    • Inhibitors
    • Drugs

Connections between topic areas Semantic bridges

For Celecoxib, one of the stronger structural bridges in this analysis connects Celecoxib with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CelecoxibOverview · splits 75 ⟂ 31
CelecoxibAdverse effects · splits 80 ⟂ 26
CelecoxibHistory · splits 89 ⟂ 17
CelecoxibResearch · splits 95 ⟂ 11
CelecoxibSociety and culture · splits 98 ⟂ 8
CelecoxibMechanism of action · splits 99 ⟂ 7
CelecoxibMedical uses · splits 101 ⟂ 5

Map overview Semantic statistics

Celecoxib

Nodes106
Edges105
Triples168
Avg. degree1.98
Density0.018868
Components1

Source & methodology

TTTA analyzes the structure around Celecoxib to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Celecoxib · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.