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Disintegrin: Operation, Other sources of disintegrin proteins & Evolution of disintegrin family

Disintegrins are a family of small proteins (45–84 amino acids in length) from viper venoms that function as potent inhibitors of both platelet aggregation and integrin-dependent cell adhesion.

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Disintegrin topic overview

The analysis highlights Operation, Other sources of disintegrin proteins and Evolution of disintegrin family as prominent areas in the source structure around Disintegrin.

Related topics
31
Source areas
4
Connected nodes
35
Extracted relationships
54
Concept neighborhoods
18
Bridge connections
35

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Operation · 15 topics
Other sources of disintegrin proteins · 8 topics
Overview · 6 topics
Evolution of disintegrin family · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR001762 · PF00200
Available protein structures:
IPR001762 · PF00200
InterPro
IPR001762
Membranome
538
OPM protein
2ao7
OPM superfamily
227

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Operation

Evolution of disintegrin family

Other sources of disintegrin proteins

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Disintegrin connects Entity context

The extracted context around Disintegrin shows recurring relationship patterns in the source. For example, Disintegrin → ADAM, ADAM2, ADAM7, ADAMTS, ADAMTS13, C-terminal, Disintegrin-like, EAP, HR1B, Ht-e, It, Mammalian, N-terminal, PH30, Some, Structurally, Such, The, Von Willebrand Another extracted example is Disintegrin → ADP, Arg-Gly-Asp, Disintegrins, IIb-IIIa, Integrins, KGD, Lys-Gly-Asp, RGD, The, They. Use these groups to spot repeated connection types before inspecting the individual relationships.

Disintegrin

Top relations

related to Other sources of disintegrin proteins · 19
Disintegrin → ADAM, ADAM2, ADAM7, ADAMTS, ADAMTS13, C-terminal, Disintegrin-like, EAP, HR1B, Ht-e, It, Mammalian, N-terminal, PH30, Some, Structurally, Such, The, Von Willebrand
related to Operation · 10
Disintegrin → ADP, Arg-Gly-Asp, Disintegrins, IIb-IIIa, Integrins, KGD, Lys-Gly-Asp, RGD, The, They
related to Evolution of disintegrin family · 6
Disintegrin → ADAM, Colubroidea, Disintegrins, Small, Snake, Viperidae
related to External links · 4
Disintegrin → Disintegrins, Medicine Medical Subject Headings, MeSH, National Library
AlphaFold · 2
Disintegrin → IPR001762, PF00200
Available protein structures: · 2
Disintegrin → IPR001762, PF00200
related to Types of disintegrin · 2
Disintegrin → Crotalus, Disintegrins
InterPro · 1
Disintegrin → IPR001762
Membranome · 1
Disintegrin → 538
OPM protein · 1
Disintegrin → 2ao7

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

disintegrins protein adam7 platelet snake aggregation proteins family large venom found n-terminal small metalloproteinases sperm ph30 contains adhesion adam receptors

Disintegrin relationships Subject–Predicate–Object triples

TTTA extracted 54 structured relationships around Disintegrin. Examples in this analysis include Disintegrin → AlphaFold → IPR001762 and Disintegrin → AlphaFold → PF00200. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
DisintegrinAlphaFoldIPR0017621.00infobox
DisintegrinAlphaFoldPF002001.00infobox
DisintegrinAvailable protein structures:IPR0017621.00infobox
DisintegrinAvailable protein structures:PF002001.00infobox
DisintegrinInterProIPR0017621.00infobox
DisintegrinMembranome5381.00infobox
DisintegrinOPM protein2ao71.00infobox
DisintegrinOPM superfamily2271.00infobox
DisintegrinPDBIPR001762 PF00200 (ECOD; PDBsum)1.00infobox
DisintegrinPfamPF002001.00infobox
DisintegrinPROSITEPDOC003511.00infobox
DisintegrinSCOP21kst / SCOPe / SUPFAM1.00infobox
DisintegrinSymbolDisintegrin1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Disintegrin bring nearby vocabulary together. In this analysis, examples include N-terminal, Contains and Domain. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • protein family
    • Small
    • Ph30
    • Dimeric
    • Medium
    • Adam
    • Proteins
    • Large
    • Adam2
    • Evolution
    • Involved
    • Platelets
    • Superfamily
  • evolution of disintegrin family
    • Small
    • N-terminal
    • Contains
    • Dimeric
    • Medium
    • Domain
    • Platelets
    • Proteins
    • Superfamily
    • Zinc
    • Large
    • Adam
  • other sources of disintegrin proteins
    • N-terminal
    • Contains
    • Domain
    • Zinc
    • Large
    • Adam7
    • Evolution
    • Platelets
    • Superfamily
    • Disintegrin
    • Family
    • Proteins
  • Disintegrin
    • N-terminal
    • Contains
    • Domain
    • Zinc
    • Large
    • Adam7
    • Family
    • Proteins
    • Protein
    • Evolution
    • Platelets
    • Superfamily
  • disintegrin
    • N-terminal
    • Contains
    • Domain
    • Zinc
    • Large
    • Adam7
    • Family
    • Proteins
    • Protein
    • Evolution
    • Platelets
    • Superfamily
  • adam
    • Protein
    • Venom
    • Snake
    • Adam2
    • Adamts13
    • Amino
    • Evolution
    • Disintegrins
    • Adhesion
    • Dimeric
    • Factor
    • Medium
  • cell adhesion
    • Adamts13
    • Aggregation
    • Platelet
    • Factor
    • Found
    • Integrins
    • Adam2
    • Adhesion
    • Amino
    • Cell
    • Involved
    • Receptors
  • amino acids
    • Acids
    • Amino
    • Family
    • Small
    • Cell
    • Adam
    • Adhesion
    • Dimeric
    • Disintegrins
    • Medium
    • Metalloproteinases
    • Proteins

Connections between topic areas Semantic bridges

For Disintegrin, one of the stronger structural bridges in this analysis connects Disintegrin with Operation. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
DisintegrinOperation · splits 20 ⟂ 16
DisintegrinOther sources of disintegrin proteins · splits 27 ⟂ 9
DisintegrinOverview · splits 29 ⟂ 7
DisintegrinEvolution of disintegrin family · splits 33 ⟂ 3

Map overview Semantic statistics

Disintegrin

Nodes36
Edges35
Triples54
Avg. degree1.94
Density0.055556
Components1

Source & methodology

TTTA analyzes the structure around Disintegrin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Operation, Other sources of disintegrin proteins & Evolution of disintegrin family, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Disintegrin · EN edition · Analysis: TopicsToTalkAbout

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