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ADAM2: Function & Overview

Disintegrin and metalloproteinase domain-containing protein 2 or Beta-fertilin is an enzyme that in humans is encoded by the ADAM2 gene.

Language: English [EN]
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ADAM2 topic overview

The analysis highlights Function and Overview as prominent areas in the source structure around ADAM2.

Related topics
5
Source areas
2
Connected nodes
7
Extracted relationships
79
Concept neighborhoods
5
Bridge connections
7

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 3 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ADAM2, CRYN1, CRYN2, CT15, FTNB, PH-30b, PH30, PH30-beta, ADAM metallopeptidase domain 2
Band
8p11.22 · 14 D1|14 34.36 cM
Bgee
testicle · left testis · right testis · gonad · placenta
BioGPS
More reference expression data
Chr.
Chromosome 8 (human) · Chromosome 14 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ADAM2 connects Entity context

The extracted context around ADAM2 shows recurring relationship patterns in the source. For example, ADAM2 → appendix, blastocyst, digastric muscle, duodenum, endocrine system, gonad, islet of Langerhans, left testis, monocyte, morula, myeloid leukocyte, neural tube, placenta, prostate, right testis, seminiferous tubule, spermatid, spermatocyte, testicle Another extracted example is ADAM2 → adult behavior, binding of sperm to zona pellucida, cell adhesion, cell surface, fusion of sperm to egg plasma membrane involved in single fertilization, integral component of membrane, integral component of plasma membrane, integrin binding, membrane, metalloendopeptidase activity, metallopeptidase activity, plasma membrane, positive regulation of gene expression, protein-containing complex, proteolysis, single fertilization, visual learning. Use these groups to spot repeated connection types before inspecting the individual relationships.

ADAM2

Top relations

Bgee · 19
ADAM2 → appendix, blastocyst, digastric muscle, duodenum, endocrine system, gonad, islet of Langerhans, left testis, monocyte, morula, myeloid leukocyte, neural tube, placenta, prostate, right testis, seminiferous tubule, spermatid, spermatocyte, testicle
RNA expression pattern · 19
ADAM2 → appendix, blastocyst, digastric muscle, duodenum, endocrine system, gonad, islet of Langerhans, left testis, monocyte, morula, myeloid leukocyte, neural tube, placenta, prostate, right testis, seminiferous tubule, spermatid, spermatocyte, testicle
Gene ontology · 17
ADAM2 → adult behavior, binding of sperm to zona pellucida, cell adhesion, cell surface, fusion of sperm to egg plasma membrane involved in single fertilization, integral component of membrane, integral component of plasma membrane, integrin binding, membrane, metalloendopeptidase activity, metallopeptidase activity, plasma membrane, positive regulation of gene expression, protein-containing complex, proteolysis, single fertilization, visual learning
related to External links · 4
ADAM2 → Human ADAM2, M12, The MEROPS, UCSC Genome Browser
Band · 2
ADAM2 → 14 D1|14 34.36 cM, 8p11.22
Chr. · 2
ADAM2 → Chromosome 14 (mouse), Chromosome 8 (human)
End · 2
ADAM2 → 39,838,227 bp, 66,315,182 bp
Aliases · 1
ADAM2 → ADAM2, CRYN1, CRYN2, CT15, FTNB, PH-30b, PH30, PH30-beta, ADAM metallopeptidase domain 2
BioGPS · 1
ADAM2 → More reference expression data
Databases · 1
ADAM2 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene human chr band chromosome location mouse protein function external disintegrin metallopeptidase 838 227 end 39 14 d1 34

ADAM2 relationships Subject–Predicate–Object triples

TTTA extracted 79 structured relationships around ADAM2. Examples in this analysis include ADAM2 → Aliases → ADAM2, CRYN1, CRYN2, CT15, FTNB, PH-30b, PH30, PH30-beta, ADAM metallopeptidase domain 2 and ADAM2 → Band → 8p11.22. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ADAM2AliasesADAM2, CRYN1, CRYN2, CT15, FTNB, PH-30b, PH30, PH30-beta, ADAM metallopeptidase domain 21.00infobox
ADAM2Band8p11.221.00infobox
ADAM2Band14 D1|14 34.36 cM1.00infobox
ADAM2Bgeetesticle1.00infobox
ADAM2Bgeeleft testis1.00infobox
ADAM2Bgeeright testis1.00infobox
ADAM2Bgeegonad1.00infobox
ADAM2Bgeeplacenta1.00infobox
ADAM2Bgeemyeloid leukocyte1.00infobox
ADAM2Bgeemonocyte1.00infobox
ADAM2Bgeeprostate1.00infobox
ADAM2Bgeeappendix1.00infobox
ADAM2Bgeespermatocyte1.00infobox
ADAM2Bgeespermatid1.00infobox
ADAM2Bgeeseminiferous tubule1.00infobox
ADAM2Bgeemorula1.00infobox
ADAM2Bgeeblastocyst1.00infobox
ADAM2Bgeeduodenum1.00infobox
ADAM2Bgeeneural tube1.00infobox
ADAM2Bgeeendocrine system1.00infobox
ADAM2Bgeeislet of Langerhans1.00infobox
ADAM2Bgeedigastric muscle1.00infobox
ADAM2BioGPSMore reference expression data1.00infobox
ADAM2Chr.Chromosome 8 (human)1.00infobox
ADAM2Chr.Chromosome 14 (mouse)1.00infobox
ADAM2DatabasesNCBI: entry; OMA: entry1.00infobox
ADAM2End39,838,227 bp1.00infobox
ADAM2End66,315,182 bp1.00infobox
ADAM2EnsemblENSG00000104755 ENSG000002762861.00infobox
ADAM2Entrez25151.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ADAM2 bring nearby vocabulary together. In this analysis, examples include Gene, Location and Adam. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • ADAM2
    • Gene
    • Location
    • Adam
    • Disintegrin
    • Domain
    • Function
    • Human
    • Metallopeptidase
    • Protein
    • Ucsc
    • Chromosome
    • Bp
  • adam2
    • Gene
    • Location
    • Adam
    • Disintegrin
    • Domain
    • Function
    • Human
    • Metallopeptidase
    • Protein
    • Ucsc
    • Chromosome
    • Bp
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Adam
    • D1
    • Domain
    • End
    • Function
    • Metallopeptidase
    • Mouse
  • function
    • Domain
    • Metallopeptidase
    • Chromosome
    • Location
    • Bp
    • Chr
    • Gene
    • Human
    • Biological
    • Cell
    • D1
    • End
  • enzyme
    • Metalloproteinase
    • Protein
    • Gene

Connections between topic areas Semantic bridges

For ADAM2, one of the stronger structural bridges in this analysis connects ADAM2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ADAM2Function · splits 4 ⟂ 4
ADAM2Overview · splits 5 ⟂ 3

Map overview Semantic statistics

ADAM2

Nodes8
Edges7
Triples79
Avg. degree1.75
Density0.25
Components1

Source & methodology

TTTA analyzes the structure around ADAM2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ADAM2 · EN edition · Analysis: TopicsToTalkAbout

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