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Nucleotide

Nucleotides are organic molecules composed of a nitrogenous base, a pentose sugar and a phosphate. They serve as monomeric units of the nucleic acid polymers – deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth. Nucleotides are obtained in the diet and are also synthesized from…

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Overview

Structure

Synthesis

Prebiotic synthesis of nucleotides

Unnatural base pair (UBP)

Medical applications of synthetic nucleotides

Abbreviation codes for degenerate bases

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Map overview Semantic statistics

Nucleotide

Nodes158
Edges157
Triples90
Avg. degree1.99
Density0.012658
Components1

How this topic connects Entity context

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Nucleotide

Top relations

has application · 20
Nucleotide → Antisense, Antiviral, ASO, ASO-based, CRISPR-Cas9, Entecavir, Examples, Hepatitis, HIV, Lamivudine, Mericitabine, NRTIs, On, RNA, Sofosbuvir, Spinal, Synthetic, Telbivudine, Tenofovir, The
related to Quantification of dNTP pools · 17
Nucleotide → Beyond, Dcd, DNA, Furthermore, HRMS, LC-MS, LC-MS/MS, Modern, MRM, MS-based, Multiple Reaction Monitoring, Orbitrap, Recent, The, Their, Time-of-Flight, TOF
related to Abbreviation codes for degenerate bases · 9
Nucleotide → Apart, Inosine, PCR, Some, T/U, The IUPAC, These, This, While
see also · 9
Nucleotide → Biology, BiologyChromosomeGeneGeneticsNucleic, Compound, DNAArtificially Expanded Genetic Information, Hachimoji DNA, Nitrogen-containing, RNA, Succession, System
related to Prebiotic synthesis of nucleotides · 8
Nucleotide → Becker, Complex, Darwinian, Purine, RNA, The RNA, Theories, Thus
related to Unnatural base pair (UBP) · 7
Nucleotide → An, DNA, Examples, These, This, UBP, UBPs
related to Purine ribonucleotide synthesis · 5
Nucleotide → AMP, GMP, IMP, The, Thus
related to Structure · 5
Nucleotide → DNA, In, Individual, These, With
related to Synthesis · 2
Nucleotide → In, Nucleotides

Important terminology Word statistics

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Important terminology

nucleotides acid purine pyrimidine phosphate rna also group used dna synthesis reaction form ribose base molecules sugar unit synthesized atp

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
LC-MS/MS with triple quadrupole mass spectrometersinstance ofadvanced techniques0.80text
dUTPinstance ofnon-canonical variants0.80text
methylated dCTP derivatives also exist within the nucleotide poolinstance ofnon-canonical variants0.80text
Mericitabineinstance ofagents0.80text
Lamivudineinstance ofagents0.80text
Entecavirinstance ofagents0.80text
Telbivudine must first undergo metabolization via phosphorylation to become activated.Antisense oligonucleotidesinstance ofagents0.80text
CRISPR-Cas9instance ofsynthetic nucleotides can be used to design gRNA which are essential for the proper function of gene-editing technologies0.80text
Nucleotidehas applicationThe0.60section
Nucleotidehas applicationAntiviral0.60section
Nucleotidehas applicationHepatitis0.60section
Nucleotidehas applicationHIV0.60section

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