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Primary hyperoxaluria is a rare condition (autosomal recessive) resulting in increased excretion of oxalate (up to 600 mg a day from normal 50 mg a day), with oxalate stones being common.
Gene Therapy, Diagnosis & Signs and symptoms
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hyperoxaluria primary oxalate ph1 kidney treatment gene urine patients clinical failure ph3 stones severe ph2 symptoms glyoxylate disease children adults
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Primary hyperoxaluria | Specialty | Obstetrics and gynaecology, urology, medical genetics, endocrinology | 1.00 | infobox |
| Primary hyperoxaluria | is a | rare condition | 0.90 | text |
| anaemia | instance of | Severe cases may develop haematological problems | 0.80 | text |
| thrombocytopaenia | instance of | Severe cases may develop haematological problems | 0.80 | text |
| kidney stones in infants or children | instance of | DiagnosisA diagnosis of primary hyperoxaluria is suspected based on presenting patient characteristics | 0.80 | text |
| recurrent kidney stones in adults | instance of | DiagnosisA diagnosis of primary hyperoxaluria is suspected based on presenting patient characteristics | 0.80 | text |
| or family history of hyperoxaluria | instance of | DiagnosisA diagnosis of primary hyperoxaluria is suspected based on presenting patient characteristics | 0.80 | text |
| Primary hyperoxaluria | has treatment | Increased | 0.60 | section |
| Primary hyperoxaluria | has treatment | In | 0.60 | section |
| Primary hyperoxaluria | has treatment | Vitamin B6 | 0.60 | section |
| Primary hyperoxaluria | has treatment | PH1 | 0.60 | section |
| Primary hyperoxaluria | has treatment | Conversely | 0.60 | section |
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