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DDX20

Probable ATP-dependent RNA helicase DDX20, also known as DEAD-box helicase 20 and gem-associated protein 3 (GEMIN3), is an enzyme that in humans is encoded by the DDX20 gene.

Interactions, Function & Clinical significance

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Interactions

14 related topics

Function

8 related topics

Clinical significance

7 related topics

Overview

2 related topics

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3.6.1.15
3.6.4.13
Aliases
DDX20, DP103, GEMIN3, DEAD-box helicase 20
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2OXC, 3B7G
Band
1p13.2 · 3|3 F2.2
Bgee
sperm · left testis · right testis · tibialis anterior muscle · secondary oocyte

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Overview

Function

Clinical significance

Interactions

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Map overview Semantic statistics

DDX20

Nodes36
Edges35
Triples129
Avg. degree1.94
Density0.055556
Components1

How this topic connects Entity context

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DDX20

Top relations

Gene ontology · 36
DDX20 → ATP binding, cytoplasm, cytoskeleton, cytosol, DNA binding, gemini of coiled bodies, helicase activity, histone deacetylase binding, hydrolase activity, import into nucleus, membrane, mRNA processing, negative regulation of cell population proliferation, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nuclear body, nucleic acid binding, nucleolus, nucleoplasm, nucleotide binding
Bgee · 20
DDX20 → deltoid muscle, epiblast, genital tubercle, gonad, left testis, mandibular prominence, maxillary prominence, mucosa of ileum, otic placode, otic vesicle, pancreatic epithelial cell, right testis, saccule, secondary oocyte, seminiferous tubule, sperm, spermatid, spermatocyte, testicle, tibialis anterior muscle
RNA expression pattern · 20
DDX20 → deltoid muscle, epiblast, genital tubercle, gonad, left testis, mandibular prominence, maxillary prominence, mucosa of ileum, otic placode, otic vesicle, pancreatic epithelial cell, right testis, saccule, secondary oocyte, seminiferous tubule, sperm, spermatid, spermatocyte, testicle, tibialis anterior muscle
related to Clinical significance · 11
DDX20 → DP103, DP103/NF-κB, In, It, NF-κB, NF-κB-suppressive, PCa, Previous, Prostate, Similarly, Such
related to Interactions · 11
DDX20 → EIF2C2, GEMIN4, GEMIN5, LSM2, SMN1, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF
Band · 2
DDX20 → 1p13.2, 3|3 F2.2
Chr. · 2
DDX20 → Chromosome 1 (human), Chromosome 3 (mouse)
End · 2
DDX20 → 105,594,890 bp, 111,775,602 bp
3.6.1.15 · 1
DDX20 → ↗
3.6.4.13 · 1
DDX20 → ↗

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Important terminology

bp gene human chr band chromosome rna function activity helicase protein location may cancer nf-κb enzyme mouse dp103 complex smn

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DDX203.6.1.151.00infobox
DDX203.6.4.131.00infobox
DDX20AliasesDDX20, DP103, GEMIN3, DEAD-box helicase 201.00infobox
DDX20Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2OXC, 3B7G1.00infobox
DDX20Band1p13.21.00infobox
DDX20Band3|3 F2.21.00infobox
DDX20Bgeesperm1.00infobox
DDX20Bgeeleft testis1.00infobox
DDX20Bgeeright testis1.00infobox
DDX20Bgeetibialis anterior muscle1.00infobox
DDX20Bgeesecondary oocyte1.00infobox
DDX20Bgeetesticle1.00infobox
DDX20Bgeegonad1.00infobox
DDX20Bgeepancreatic epithelial cell1.00infobox
DDX20Bgeemucosa of ileum1.00infobox
DDX20Bgeedeltoid muscle1.00infobox
DDX20Bgeeotic placode1.00infobox
DDX20Bgeeotic vesicle1.00infobox
DDX20Bgeesaccule1.00infobox
DDX20Bgeespermatid1.00infobox
DDX20Bgeeseminiferous tubule1.00infobox
DDX20Bgeespermatocyte1.00infobox
DDX20Bgeeepiblast1.00infobox
DDX20Bgeegenital tubercle1.00infobox
DDX20Bgeemaxillary prominence1.00infobox
DDX20Bgeemandibular prominence1.00infobox
DDX20BioGPSMore reference expression data1.00infobox
DDX20Chr.Chromosome 1 (human)1.00infobox
DDX20Chr.Chromosome 3 (mouse)1.00infobox
DDX20DatabasesNCBI: entry; OMA: entry1.00infobox

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