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EIF2C2

Protein argonaute-2 is a protein that in humans is encoded by the EIF2C2 gene.

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6 related topics

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7 related topics

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Aliases
AGO2, EIF2C2, Q10, argonaute 2, RISC catalytic component, PPD, CASC7, LINC00980, argonaute RISC catalytic component 2, LESKRES
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3LUC, 3LUD, 3LUG, 3LUH, 3LUJ, 3LUK, 3QX8, 3QX9, 4F3T, 4OLA, 4OLB, 4W5N, 4W5O, 4W5Q, 4W5R, 4W5T, 4Z4C, 4Z4D,…
Band
8q24.3 · 15|15 D3
Bgee
epithelium of colon · cartilage tissue · tail of epididymis · superficial temporal artery · trabecular bone
BioGPS
n/a
Chr.
Chromosome 8 (human) · Chromosome 15 (mouse)

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EIF2C2

Nodes16
Edges15
Triples131
Avg. degree1.88
Density0.125
Components1

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EIF2C2

Top relations

Gene ontology · 63
EIF2C2 → cell junction, cytoplasm, cytosol, dendrite, double-stranded RNA binding, endonuclease activity, endoribonuclease activity, endoribonuclease activity, cleaving miRNA-paired mRNA, endoribonuclease activity, cleaving siRNA-paired mRNA, endoribonuclease activity, producing 5'-phosphomonoesters, extracellular exosome, gene silencing, hydrolase activity, membrane, metal ion binding, miRNA binding, miRNA metabolic process, miRNA-mediated gene silencing by inhibition of translation, mRNA binding, mRNA cap binding
Bgee · 20
EIF2C2 → Achilles tendon, anterior amygdaloid area, aortic valve, ascending aorta, cartilage tissue, corpus epididymis, epithelium of colon, foot, hand, human fetus, lower lobe of lung, mucosa of paranasal sinus, paraventricular nucleus of hypothalamus, superficial temporal artery, suprachiasmatic nucleus, supraoptic nucleus, tail of epididymis, tendon, trabecular bone, ventromedial nucleus
RNA expression pattern · 20
EIF2C2 → Achilles tendon, anterior amygdaloid area, aortic valve, ascending aorta, cartilage tissue, corpus epididymis, epithelium of colon, foot, hand, human fetus, lower lobe of lung, mucosa of paranasal sinus, paraventricular nucleus of hypothalamus, superficial temporal artery, suprachiasmatic nucleus, supraoptic nucleus, tail of epididymis, tendon, trabecular bone, ventromedial nucleus
related to Interactions · 5
EIF2C2 → DDX20, DICER1, FMRP, FXR1P, FXR2P
Band · 2
EIF2C2 → 15|15 D3, 8q24.3
Chr. · 2
EIF2C2 → Chromosome 15 (mouse), Chromosome 8 (human)
End · 2
EIF2C2 → 140,635,633 bp, 73,056,784 bp
Aliases · 1
EIF2C2 → AGO2, EIF2C2, Q10, argonaute 2, RISC catalytic component, PPD, CASC7, LINC00980, argonaute RISC catalytic component 2, LESKRES
Available structures · 1
EIF2C2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3LUC, 3LUD, 3LUG, 3LUH, 3LUJ, 3LUK, 3QX8, 3QX9, 4F3T, 4OLA, 4OLB, 4W5N, 4W5O, 4W5Q, 4W5R, 4W5T, 4Z4C, 4Z4D,…
BioGPS · 1
EIF2C2 → n/a

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Important terminology

gene bp chr human band protein chromosome location encoded play role argonaute ago2 mouse interact dicer1 rna interference silencing risc

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
EIF2C2AliasesAGO2, EIF2C2, Q10, argonaute 2, RISC catalytic component, PPD, CASC7, LINC00980, argonaute RISC catalytic component 2, LESKRES1.00infobox
EIF2C2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3LUC, 3LUD, 3LUG, 3LUH, 3LUJ, 3LUK, 3QX8, 3QX9, 4F3T, 4OLA, 4OLB, 4W5N, 4W5O, 4W5Q, 4W5R, 4W5T, 4Z4C, 4Z4D,…1.00infobox
EIF2C2Band8q24.31.00infobox
EIF2C2Band15|15 D31.00infobox
EIF2C2Bgeeepithelium of colon1.00infobox
EIF2C2Bgeecartilage tissue1.00infobox
EIF2C2Bgeetail of epididymis1.00infobox
EIF2C2Bgeesuperficial temporal artery1.00infobox
EIF2C2Bgeetrabecular bone1.00infobox
EIF2C2Bgeecorpus epididymis1.00infobox
EIF2C2Bgeemucosa of paranasal sinus1.00infobox
EIF2C2Bgeelower lobe of lung1.00infobox
EIF2C2Bgeetendon1.00infobox
EIF2C2BgeeAchilles tendon1.00infobox
EIF2C2Bgeeascending aorta1.00infobox
EIF2C2Bgeehand1.00infobox
EIF2C2Bgeeaortic valve1.00infobox
EIF2C2Bgeehuman fetus1.00infobox
EIF2C2Bgeesupraoptic nucleus1.00infobox
EIF2C2Bgeeventromedial nucleus1.00infobox
EIF2C2Bgeeanterior amygdaloid area1.00infobox
EIF2C2Bgeesuprachiasmatic nucleus1.00infobox
EIF2C2Bgeefoot1.00infobox
EIF2C2Bgeeparaventricular nucleus of hypothalamus1.00infobox
EIF2C2BioGPSn/a1.00infobox
EIF2C2Chr.Chromosome 8 (human)1.00infobox
EIF2C2Chr.Chromosome 15 (mouse)1.00infobox
EIF2C2DatabasesNCBI: entry; OMA: entry1.00infobox
EIF2C2End140,635,633 bp1.00infobox
EIF2C2End73,056,784 bp1.00infobox

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