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EIF2C2: Interactions & Overview

Protein argonaute-2 is a protein that in humans is encoded by the EIF2C2 gene.

Language: English [EN]
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EIF2C2 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around EIF2C2.

Related topics
13
Source areas
2
Connected nodes
15
Extracted relationships
131
Concept neighborhoods
9
Bridge connections
15

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 7 topics
Interactions · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
AGO2, EIF2C2, Q10, argonaute 2, RISC catalytic component, PPD, CASC7, LINC00980, argonaute RISC catalytic component 2, LESKRES
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3LUC, 3LUD, 3LUG, 3LUH, 3LUJ, 3LUK, 3QX8, 3QX9, 4F3T, 4OLA, 4OLB, 4W5N, 4W5O, 4W5Q, 4W5R, 4W5T, 4Z4C, 4Z4D,…
Band
8q24.3 · 15|15 D3
Bgee
epithelium of colon · cartilage tissue · tail of epididymis · superficial temporal artery · trabecular bone
BioGPS
n/a
Chr.
Chromosome 8 (human) · Chromosome 15 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How EIF2C2 connects Entity context

The extracted context around EIF2C2 shows recurring relationship patterns in the source. For example, EIF2C2 → cell junction, cytoplasm, cytosol, dendrite, double-stranded RNA binding, endonuclease activity, endoribonuclease activity, endoribonuclease activity, cleaving miRNA-paired mRNA, endoribonuclease activity, cleaving siRNA-paired mRNA, endoribonuclease activity, producing 5'-phosphomonoesters, extracellular exosome, gene silencing, hydrolase activity, membrane, metal ion binding, miRNA binding, miRNA metabolic process, miRNA-mediated gene silencing by inhibition of translation, mRNA binding, mRNA cap binding Another extracted example is EIF2C2 → Achilles tendon, anterior amygdaloid area, aortic valve, ascending aorta, cartilage tissue, corpus epididymis, epithelium of colon, foot, hand, human fetus, lower lobe of lung, mucosa of paranasal sinus, paraventricular nucleus of hypothalamus, superficial temporal artery, suprachiasmatic nucleus, supraoptic nucleus, tail of epididymis, tendon, trabecular bone, ventromedial nucleus. Use these groups to spot repeated connection types before inspecting the individual relationships.

EIF2C2

Top relations

Gene ontology · 63
EIF2C2 → cell junction, cytoplasm, cytosol, dendrite, double-stranded RNA binding, endonuclease activity, endoribonuclease activity, endoribonuclease activity, cleaving miRNA-paired mRNA, endoribonuclease activity, cleaving siRNA-paired mRNA, endoribonuclease activity, producing 5'-phosphomonoesters, extracellular exosome, gene silencing, hydrolase activity, membrane, metal ion binding, miRNA binding, miRNA metabolic process, miRNA-mediated gene silencing by inhibition of translation, mRNA binding, mRNA cap binding
Bgee · 20
EIF2C2 → Achilles tendon, anterior amygdaloid area, aortic valve, ascending aorta, cartilage tissue, corpus epididymis, epithelium of colon, foot, hand, human fetus, lower lobe of lung, mucosa of paranasal sinus, paraventricular nucleus of hypothalamus, superficial temporal artery, suprachiasmatic nucleus, supraoptic nucleus, tail of epididymis, tendon, trabecular bone, ventromedial nucleus
RNA expression pattern · 20
EIF2C2 → Achilles tendon, anterior amygdaloid area, aortic valve, ascending aorta, cartilage tissue, corpus epididymis, epithelium of colon, foot, hand, human fetus, lower lobe of lung, mucosa of paranasal sinus, paraventricular nucleus of hypothalamus, superficial temporal artery, suprachiasmatic nucleus, supraoptic nucleus, tail of epididymis, tendon, trabecular bone, ventromedial nucleus
related to Interactions · 5
EIF2C2 → DDX20, DICER1, FMRP, FXR1P, FXR2P
Band · 2
EIF2C2 → 15|15 D3, 8q24.3
Chr. · 2
EIF2C2 → Chromosome 15 (mouse), Chromosome 8 (human)
End · 2
EIF2C2 → 140,635,633 bp, 73,056,784 bp
Aliases · 1
EIF2C2 → AGO2, EIF2C2, Q10, argonaute 2, RISC catalytic component, PPD, CASC7, LINC00980, argonaute RISC catalytic component 2, LESKRES
Available structures · 1
EIF2C2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3LUC, 3LUD, 3LUG, 3LUH, 3LUJ, 3LUK, 3QX8, 3QX9, 4F3T, 4OLA, 4OLB, 4W5N, 4W5O, 4W5Q, 4W5R, 4W5T, 4Z4C, 4Z4D,…
BioGPS · 1
EIF2C2 → n/a

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp chr human band protein chromosome location encoded play role argonaute ago2 mouse interact dicer1 rna interference silencing risc

EIF2C2 relationships Subject–Predicate–Object triples

TTTA extracted 131 structured relationships around EIF2C2. Examples in this analysis include EIF2C2 → Aliases → AGO2, EIF2C2, Q10, argonaute 2, RISC catalytic component, PPD, CASC7, LINC00980, argonaute RISC catalytic component 2, LESKRES and EIF2C2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3LUC, 3LUD, 3LUG, 3LUH, 3LUJ, 3LUK, 3QX8, 3QX9, 4F3T, 4OLA, 4OLB, 4W5N, 4W5O, 4W5Q, 4W5R, 4W5T, 4Z4C, 4Z4D,…. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
EIF2C2AliasesAGO2, EIF2C2, Q10, argonaute 2, RISC catalytic component, PPD, CASC7, LINC00980, argonaute RISC catalytic component 2, LESKRES1.00infobox
EIF2C2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3LUC, 3LUD, 3LUG, 3LUH, 3LUJ, 3LUK, 3QX8, 3QX9, 4F3T, 4OLA, 4OLB, 4W5N, 4W5O, 4W5Q, 4W5R, 4W5T, 4Z4C, 4Z4D,…1.00infobox
EIF2C2Band8q24.31.00infobox
EIF2C2Band15|15 D31.00infobox
EIF2C2Bgeeepithelium of colon1.00infobox
EIF2C2Bgeecartilage tissue1.00infobox
EIF2C2Bgeetail of epididymis1.00infobox
EIF2C2Bgeesuperficial temporal artery1.00infobox
EIF2C2Bgeetrabecular bone1.00infobox
EIF2C2Bgeecorpus epididymis1.00infobox
EIF2C2Bgeemucosa of paranasal sinus1.00infobox
EIF2C2Bgeelower lobe of lung1.00infobox
EIF2C2Bgeetendon1.00infobox
EIF2C2BgeeAchilles tendon1.00infobox
EIF2C2Bgeeascending aorta1.00infobox
EIF2C2Bgeehand1.00infobox
EIF2C2Bgeeaortic valve1.00infobox
EIF2C2Bgeehuman fetus1.00infobox
EIF2C2Bgeesupraoptic nucleus1.00infobox
EIF2C2Bgeeventromedial nucleus1.00infobox
EIF2C2Bgeeanterior amygdaloid area1.00infobox
EIF2C2Bgeesuprachiasmatic nucleus1.00infobox
EIF2C2Bgeefoot1.00infobox
EIF2C2Bgeeparaventricular nucleus of hypothalamus1.00infobox
EIF2C2BioGPSn/a1.00infobox
EIF2C2Chr.Chromosome 8 (human)1.00infobox
EIF2C2Chr.Chromosome 15 (mouse)1.00infobox
EIF2C2DatabasesNCBI: entry; OMA: entry1.00infobox
EIF2C2End140,635,633 bp1.00infobox
EIF2C2End73,056,784 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around EIF2C2 bring nearby vocabulary together. In this analysis, examples include Ago2, Component and Risc. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Ago2
    • Argonaute
    • Component
    • Dicer1
    • End
    • Interact
    • Interference
  • EIF2C2
    • Ago2
    • Component
    • Risc
    • Search
    • Gene
    • Location
    • Protein
    • Chromosome
    • Human
    • Bp
    • Chr
    • Humans
  • eif2c2
    • Ago2
    • Component
    • Risc
    • Search
    • Gene
    • Location
    • Protein
    • Chromosome
    • Human
    • Bp
    • Chr
    • Humans
  • rna interference
    • Rna
    • Member
    • Proteins
    • Ago2
    • Component
    • Dicer1
    • End
    • Interact
    • Mouse
    • Play
    • Risc
    • Role
  • dicer1
    • Interact
    • Silencing
    • Ago2
    • Component
    • End
    • Gene
    • Interference
    • Mouse
    • Play
    • Risc
    • Rna
    • Role
  • argonaute
    • Encodes
    • Family
    • Member
    • Proteins
    • Ago2
    • Component
    • Gene
    • Interference
    • Play
    • Risc
    • Rna
    • Role
  • interact
    • Silencing
    • Ago2
    • Component
    • End
    • Interference
    • Mouse
    • Play
    • Risc
    • Rna
    • Role
    • Search
    • Location
  • protein
    • Risc
    • Rna
    • Search
    • Silencing

Connections between topic areas Semantic bridges

For EIF2C2, one of the stronger structural bridges in this analysis connects EIF2C2 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
EIF2C2Overview · splits 8 ⟂ 8
EIF2C2Interactions · splits 9 ⟂ 7

Map overview Semantic statistics

EIF2C2

Nodes16
Edges15
Triples131
Avg. degree1.88
Density0.125
Components1

Source & methodology

TTTA analyzes the structure around EIF2C2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — EIF2C2 · EN edition · Analysis: TopicsToTalkAbout

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