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LATS1: Regions, Overview & Interactions

Large tumor suppressor kinase 1 (LATS1) is an enzyme that in humans is encoded by the LATS1 gene.

Language: English [EN]
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LATS1 topic overview

The analysis highlights Regions, Overview and Interactions as prominent areas in the source structure around LATS1.

Related topics
27
Source areas
2
Connected nodes
29
Extracted relationships
109
Concept neighborhoods
14
Bridge connections
29

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 24 topics
Interactions · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.1
Aliases
LATS1, WARTS, wts, large tumor suppressor kinase 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4ZRK, 5BRK, 5B5W
Band
6q25.1 · 10|10 A1
Bgee
germinal epithelium · tibia · mucosa of paranasal sinus · gingival epithelium · epithelium of nasopharynx
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How LATS1 connects Entity context

The extracted context around LATS1 shows recurring relationship patterns in the source. For example, LATS1 → ATP binding, cell cycle, cell division, cytoplasm, cytoplasmic sequestering of protein, cytoskeleton, cytosol, estrogen receptor binding, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, hippo signaling, hormone-mediated signaling pathway, inner cell mass cell fate commitment, inner cell mass cellular morphogenesis, intracellular signal transduction, keratinocyte differentiation, kinase activity, magnesium ion binding, mammary gland epithelial cell differentiation, metal ion binding Another extracted example is LATS1 → epithelium of nasopharynx, ganglionic eminence, genital tubercle, germinal epithelium, gingival epithelium, granulocyte, ileum, jejunum, lens, mucosa of paranasal sinus, ovary, palpebral conjunctiva, parietal pleura, retinal pigment epithelium, seminal vesicula, tail of embryo, tibia, uterus, ventricular zone, visceral pleura. Use these groups to spot repeated connection types before inspecting the individual relationships.

LATS1

Top relations

Gene ontology · 42
LATS1 → ATP binding, cell cycle, cell division, cytoplasm, cytoplasmic sequestering of protein, cytoskeleton, cytosol, estrogen receptor binding, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, hippo signaling, hormone-mediated signaling pathway, inner cell mass cell fate commitment, inner cell mass cellular morphogenesis, intracellular signal transduction, keratinocyte differentiation, kinase activity, magnesium ion binding, mammary gland epithelial cell differentiation, metal ion binding
Bgee · 20
LATS1 → epithelium of nasopharynx, ganglionic eminence, genital tubercle, germinal epithelium, gingival epithelium, granulocyte, ileum, jejunum, lens, mucosa of paranasal sinus, ovary, palpebral conjunctiva, parietal pleura, retinal pigment epithelium, seminal vesicula, tail of embryo, tibia, uterus, ventricular zone, visceral pleura
RNA expression pattern · 20
LATS1 → epithelium of nasopharynx, ganglionic eminence, genital tubercle, germinal epithelium, gingival epithelium, granulocyte, ileum, jejunum, lens, mucosa of paranasal sinus, ovary, palpebral conjunctiva, parietal pleura, retinal pigment epithelium, seminal vesicula, tail of embryo, tibia, uterus, ventricular zone, visceral pleura
Band · 2
LATS1 → 10|10 A1, 6q25.1
Chr. · 2
LATS1 → Chromosome 10 (mouse), Chromosome 6 (human)
End · 2
LATS1 → 149,718,105 bp, 7,592,224 bp
related to Interactions · 2
LATS1 → Cdk1, Zyxin
2.7.11.1 · 1
LATS1 → ↗
Aliases · 1
LATS1 → LATS1, WARTS, wts, large tumor suppressor kinase 1
Available structures · 1
LATS1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4ZRK, 5BRK, 5B5W

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

kinase gene bp chr protein human band chromosome tumor suppressor cell complex negative activity cdc2 n-terminal location encoded region binds

LATS1 relationships Subject–Predicate–Object triples

TTTA extracted 109 structured relationships around LATS1. Examples in this analysis include LATS1 → 2.7.11.1 → ↗ and LATS1 → Aliases → LATS1, WARTS, wts, large tumor suppressor kinase 1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
LATS12.7.11.11.00infobox
LATS1AliasesLATS1, WARTS, wts, large tumor suppressor kinase 11.00infobox
LATS1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4ZRK, 5BRK, 5B5W1.00infobox
LATS1Band6q25.11.00infobox
LATS1Band10|10 A11.00infobox
LATS1Bgeegerminal epithelium1.00infobox
LATS1Bgeetibia1.00infobox
LATS1Bgeemucosa of paranasal sinus1.00infobox
LATS1Bgeegingival epithelium1.00infobox
LATS1Bgeeepithelium of nasopharynx1.00infobox
LATS1Bgeeparietal pleura1.00infobox
LATS1Bgeevisceral pleura1.00infobox
LATS1Bgeeseminal vesicula1.00infobox
LATS1Bgeeretinal pigment epithelium1.00infobox
LATS1Bgeepalpebral conjunctiva1.00infobox
LATS1Bgeegenital tubercle1.00infobox
LATS1Bgeetail of embryo1.00infobox
LATS1Bgeeuterus1.00infobox
LATS1Bgeeganglionic eminence1.00infobox
LATS1Bgeeventricular zone1.00infobox
LATS1Bgeeovary1.00infobox
LATS1Bgeelens1.00infobox
LATS1Bgeejejunum1.00infobox
LATS1Bgeegranulocyte1.00infobox
LATS1Bgeeileum1.00infobox
LATS1BioGPSMore reference expression data1.00infobox
LATS1Chr.Chromosome 6 (human)1.00infobox
LATS1Chr.Chromosome 10 (mouse)1.00infobox
LATS1DatabasesNCBI: entry; OMA: entry1.00infobox
LATS1End149,718,105 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around LATS1 bring nearby vocabulary together. In this analysis, examples include Search, Activity and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • LATS1
    • Search
    • Activity
    • Location
    • Suppressor
    • Tumor
    • Chromosome
    • Human
    • Bp
    • Chr
    • Binding
    • Cycle
    • Data
  • lats1
    • Search
    • Activity
    • Location
    • Suppressor
    • Tumor
    • Chromosome
    • Human
    • Bp
    • Chr
    • Binding
    • Cycle
    • Data
  • gene
    • Lats1
    • Location
    • Kinase
    • Chromosome
    • Human
    • Bp
    • Chr
    • Cycle
    • Large
    • Mitotic
    • Mouse
    • Search
  • hippo signaling pathway
    • Function
    • Pathway
    • Signaling
    • Binding
    • Cycle
    • Data
    • Mitotic
    • Mouse
    • Phosphorylation
    • Regulation
    • Search
    • Serine
  • serine/threonine kinase
    • Cycle
    • Mitotic
    • Serine
    • Threonine
    • Cell
    • Gene
    • Activity
    • Complex
    • Lats1
    • Negative
    • Protein
    • Binding
  • cell cycle
    • Mitotic
    • Serine
    • Threonine
    • Cycle
    • Protein
    • Gene
    • Binding
    • Cdc2
    • Data
    • Encoded
    • Function
    • Hippo
  • kinase domain
    • Gene
    • Activity
    • Complex
    • Lats1
    • Negative
    • Protein
    • Binding
    • Binds
    • Cdc2
    • Cycle
    • Encoded
    • Enzyme
  • ovarian stromal cell tumors
    • Cycle
    • Mitotic
    • Serine
    • Threonine
    • Protein
    • Gene
    • Kinase
    • Binding
    • Cdc2
    • Data
    • Encoded
    • Function

Connections between topic areas Semantic bridges

For LATS1, one of the stronger structural bridges in this analysis connects LATS1 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
LATS1Overview · splits 5 ⟂ 25
LATS1Interactions · splits 26 ⟂ 4

Map overview Semantic statistics

LATS1

Nodes30
Edges29
Triples109
Avg. degree1.93
Density0.066667
Components1

Source & methodology

TTTA analyzes the structure around LATS1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Overview & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — LATS1 · EN edition · Analysis: TopicsToTalkAbout

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