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DAB2: Interactions & Overview

Disabled homolog 2 is a protein that in humans is encoded by the DAB2 gene.

Language: English [EN]
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DAB2 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around DAB2.

Related topics
14
Source areas
2
Connected nodes
16
Extracted relationships
126
Concept neighborhoods
7
Bridge connections
16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 12 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
DAB2, DOC-2, DOC2, clathrin adaptor protein, DAB adaptor protein 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LSW
Band
5p13.1 · 15 A1|15 2.15 cM
Bgee
caput epididymis · corpus epididymis · tendon of biceps brachii · placenta · synovial joint
BioGPS
More reference expression data
Chr.
Chromosome 5 (human) · Chromosome 15 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How DAB2 connects Entity context

The extracted context around DAB2 shows recurring relationship patterns in the source. For example, DAB2 → apoptotic process, cargo receptor activity, cell differentiation, cell population proliferation, clathrin adaptor activity, clathrin-coated pit, clathrin-coated vesicle, clathrin-coated vesicle membrane, cytoplasm, cytoplasmic vesicle, cytosol, endocytosis, extracellular exosome, fibrillar center, focal adhesion, integrin-mediated signaling pathway, intracellular membrane-bounded organelle, leading edge cell differentiation, lysosomal membrane, membrane Another extracted example is DAB2 → Achilles tendon, adrenal gland, caput epididymis, corpus epididymis, dermis, efferent ductule, human kidney, left adrenal gland, placenta, proximal tubule, right adrenal cortex, right kidney, secondary oocyte, stroma of bone marrow, synovial joint, synovial membrane, tendon of biceps brachii, yolk sac, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

DAB2

Top relations

Gene ontology · 49
DAB2 → apoptotic process, cargo receptor activity, cell differentiation, cell population proliferation, clathrin adaptor activity, clathrin-coated pit, clathrin-coated vesicle, clathrin-coated vesicle membrane, cytoplasm, cytoplasmic vesicle, cytosol, endocytosis, extracellular exosome, fibrillar center, focal adhesion, integrin-mediated signaling pathway, intracellular membrane-bounded organelle, leading edge cell differentiation, lysosomal membrane, membrane
Bgee · 19
DAB2 → Achilles tendon, adrenal gland, caput epididymis, corpus epididymis, dermis, efferent ductule, human kidney, left adrenal gland, placenta, proximal tubule, right adrenal cortex, right kidney, secondary oocyte, stroma of bone marrow, synovial joint, synovial membrane, tendon of biceps brachii, yolk sac, zygote
RNA expression pattern · 19
DAB2 → Achilles tendon, adrenal gland, caput epididymis, corpus epididymis, dermis, efferent ductule, human kidney, left adrenal gland, placenta, proximal tubule, right adrenal cortex, right kidney, secondary oocyte, stroma of bone marrow, synovial joint, synovial membrane, tendon of biceps brachii, yolk sac, zygote
related to Function · 8
DAB2 → C2-like, Differentially, DOC2, DOC2A, DOC2B, Ovarian Cancer, The, This
related to Interactions · 8
DAB2 → C-src, Cdk1, DAB2IP, DVL2, DVL3, LRP2, Mothers, MYO6
Band · 2
DAB2 → 15 A1|15 2.15 cM, 5p13.1
Chr. · 2
DAB2 → Chromosome 15 (mouse), Chromosome 5 (human)
End · 2
DAB2 → 39,462,300 bp, 6,470,193 bp
Aliases · 1
DAB2 → DAB2, DOC-2, DOC2, clathrin adaptor protein, DAB adaptor protein 2
Available structures · 1
DAB2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LSW

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr human band protein chromosome mouse location end expressed function ovarian homolog clathrin adaptor search 462 300 39

DAB2 relationships Subject–Predicate–Object triples

TTTA extracted 126 structured relationships around DAB2. Examples in this analysis include DAB2 → Aliases → DAB2, DOC-2, DOC2, clathrin adaptor protein, DAB adaptor protein 2 and DAB2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LSW. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
DAB2AliasesDAB2, DOC-2, DOC2, clathrin adaptor protein, DAB adaptor protein 21.00infobox
DAB2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LSW1.00infobox
DAB2Band5p13.11.00infobox
DAB2Band15 A1|15 2.15 cM1.00infobox
DAB2Bgeecaput epididymis1.00infobox
DAB2Bgeecorpus epididymis1.00infobox
DAB2Bgeetendon of biceps brachii1.00infobox
DAB2Bgeeplacenta1.00infobox
DAB2Bgeesynovial joint1.00infobox
DAB2BgeeAchilles tendon1.00infobox
DAB2Bgeeright adrenal cortex1.00infobox
DAB2Bgeehuman kidney1.00infobox
DAB2Bgeesynovial membrane1.00infobox
DAB2Bgeeleft adrenal gland1.00infobox
DAB2Bgeeyolk sac1.00infobox
DAB2Bgeestroma of bone marrow1.00infobox
DAB2Bgeeefferent ductule1.00infobox
DAB2Bgeeright kidney1.00infobox
DAB2Bgeezygote1.00infobox
DAB2Bgeedermis1.00infobox
DAB2Bgeeadrenal gland1.00infobox
DAB2Bgeeproximal tubule1.00infobox
DAB2Bgeesecondary oocyte1.00infobox
DAB2BioGPSMore reference expression data1.00infobox
DAB2Chr.Chromosome 5 (human)1.00infobox
DAB2Chr.Chromosome 15 (mouse)1.00infobox
DAB2DatabasesNCBI: entry; OMA: entry1.00infobox
DAB2End39,462,300 bp1.00infobox
DAB2End6,470,193 bp1.00infobox
DAB2EnsemblENSG000001530711.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around DAB2 bring nearby vocabulary together. In this analysis, examples include Protein, Gene and Adaptor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • DAB2
    • Protein
    • Gene
    • Adaptor
    • Clathrin
    • Function
    • Homolog
    • Search
    • Location
    • Ovarian
    • Chromosome
    • Human
    • Bp
  • dab2
    • Protein
    • Gene
    • Adaptor
    • Clathrin
    • Function
    • Homolog
    • Search
    • Location
    • Ovarian
    • Chromosome
    • Human
    • Bp
  • gene
    • Location
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
    • A1
    • Adaptor
    • Beta
    • Clathrin
    • Doc2
    • Expressed
  • protein
    • Search
    • End
    • Location
    • Mouse
    • Cell
    • Epithelial
    • Mrna
    • Reading
    • References
    • A1
    • Beta
    • Expressed
  • interactions
    • Reading
    • References
    • Search
    • Location
    • Human
    • Protein
  • mothers against decapentaplegic homolog 2
    • Encoded
    • Humans
    • Protein
    • Gene
  • mothers against decapentaplegic homolog 3
    • Encoded
    • Humans
    • Protein
    • Gene

Connections between topic areas Semantic bridges

For DAB2, one of the stronger structural bridges in this analysis connects DAB2 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
DAB2Interactions · splits 4 ⟂ 13
DAB2Overview · splits 14 ⟂ 3

Map overview Semantic statistics

DAB2

Nodes17
Edges16
Triples126
Avg. degree1.88
Density0.117647
Components1

Source & methodology

TTTA analyzes the structure around DAB2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — DAB2 · EN edition · Analysis: TopicsToTalkAbout

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