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CSRP3

Cysteine and glycine-rich protein 3 also known as cardiac LIM protein (CLP) or muscle LIM protein (MLP) is a protein that in humans is encoded by the CSRP3 gene.

Research, Protein interactions and localization & Clinical significance

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Aliases
CSRP3, CLP, CMD1M, CMH12, CRP3, LMO4, MLP, cysteine and glycine rich protein 3
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O10, 2O13
Band
11p15.1 · 7|7 B4
Bgee
Skeletal muscle tissue of rectus abdominis · right ventricle · myocardium of left ventricle · apex of heart · biceps brachii
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 7 (mouse)

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Overview

Gene

Structure

Protein interactions and localization

Function

Animal studies

Clinical significance

Animal models

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Map overview Semantic statistics

CSRP3

Nodes85
Edges84
Triples149
Avg. degree1.98
Density0.023529
Components1

How this topic connects Entity context

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CSRP3

Top relations

Gene ontology · 41
CSRP3 → actin binding, actin cytoskeleton organization, actinin binding, cardiac muscle contraction, cardiac muscle hypertrophy, cardiac muscle tissue development, cardiac myofibril assembly, cell differentiation, cellular calcium ion homeostasis, cytoplasm, cytoskeleton, detection of muscle stretch, development of the heart, glucose homeostasis, identical protein binding, inflammatory response, insulin receptor signaling pathway, metal ion binding, multicellular organism development, muscle organ development
related to Clinical significance · 27
CSRP3 → Alterations, Biochemical, C58G, DCM, Duchenne, For, G72R, HCM, K42/fs165, K69L, K69R, L44P, MLP, MLP-b, MLP/T-cap, MLP/α-actinin, Moreover, Mutations, Q91L, R64C
Bgee · 19
CSRP3 → ankle, apex of heart, atrioventricular valve, atrium, biceps brachii, cardiac muscle tissue of right atrium, cardiac muscles, endocardial cushion, esophagus, glutes, interventricular septum, myocardium of left ventricle, myocardium of ventricle, right auricle of heart, right ventricle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, thoracic diaphragm
RNA expression pattern · 19
CSRP3 → ankle, apex of heart, atrioventricular valve, atrium, biceps brachii, cardiac muscle tissue of right atrium, cardiac muscles, endocardial cushion, esophagus, glutes, interventricular septum, myocardium of left ventricle, myocardium of ventricle, right auricle of heart, right ventricle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, thoracic diaphragm
related to External links · 11
CSRP3 → Cysteine, Familial Hypertrophic Cardiomyopathy OverviewHuman, GeneReviews/NIH/NCBI/UW, Human LMO4, LMO4, Overview, P50461, PDB, PDBe-KB, UCSC Genome Browser, UniProt
related to Gene · 4
CSRP3 → In, MLP-b, The, The CSRP3
Band · 2
CSRP3 → 11p15.1, 7|7 B4
Chr. · 2
CSRP3 → Chromosome 11 (human), Chromosome 7 (mouse)
End · 2
CSRP3 → 19,210,571 bp, 48,497,781 bp
Aliases · 1
CSRP3 → CSRP3, CLP, CMD1M, CMH12, CRP3, LMO4, MLP, cysteine and glycine rich protein 3

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Important terminology

mlp protein gene muscle localization human cardiac bp function expressed chr band also chromosome location z-line cardiomyopathy 11 cytoskeleton nucleus

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CSRP3AliasesCSRP3, CLP, CMD1M, CMH12, CRP3, LMO4, MLP, cysteine and glycine rich protein 31.00infobox
CSRP3Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O10, 2O131.00infobox
CSRP3Band11p15.11.00infobox
CSRP3Band7|7 B41.00infobox
CSRP3BgeeSkeletal muscle tissue of rectus abdominis1.00infobox
CSRP3Bgeeright ventricle1.00infobox
CSRP3Bgeemyocardium of left ventricle1.00infobox
CSRP3Bgeeapex of heart1.00infobox
CSRP3Bgeebiceps brachii1.00infobox
CSRP3BgeeSkeletal muscle tissue of biceps brachii1.00infobox
CSRP3Bgeethoracic diaphragm1.00infobox
CSRP3Bgeeglutes1.00infobox
CSRP3Bgeecardiac muscle tissue of right atrium1.00infobox
CSRP3Bgeeright auricle of heart1.00infobox
CSRP3Bgeeatrioventricular valve1.00infobox
CSRP3Bgeeendocardial cushion1.00infobox
CSRP3Bgeeinterventricular septum1.00infobox
CSRP3Bgeecardiac muscles1.00infobox
CSRP3Bgeemyocardium of ventricle1.00infobox
CSRP3Bgeeankle1.00infobox
CSRP3Bgeeatrium1.00infobox
CSRP3Bgeeesophagus1.00infobox
CSRP3Bgeesoleus muscle1.00infobox
CSRP3BioGPSMore reference expression data1.00infobox
CSRP3Chr.Chromosome 11 (human)1.00infobox
CSRP3Chr.Chromosome 7 (mouse)1.00infobox
CSRP3DatabasesNCBI: entry; OMA: entry1.00infobox
CSRP3End19,210,571 bp1.00infobox
CSRP3End48,497,781 bp1.00infobox
CSRP3EnsemblENSG000001291701.00infobox

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