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Actin filament

Actin filaments (also known as microfilaments) are protein filaments in the cytoplasm of eukaryotic cells that form part of the cytoskeleton. They are primarily composed of polymers of actin, but are modified by and interact with numerous other proteins in the cell. Actin filaments are usually about 7 nm in diameter and made up of two strands of actin.…

Art, Actin in cells & In vitro self-assembly

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Actin in cells

Signal transductionMembraneChemotaxisProfilinThymosin beta-4
21 related topics

In vitro self-assembly

NmPolymersHelicalMicrotubulesElectron micrographs
19 related topics

A proposed model – actoclampins track filament ends

LamellipodiaFilopodiaDendritic spinesIntracellularVesicles
17 related topics

Overview

Protein filamentsCytoplasmEukaryoticCellsCytoskeleton
21 related topics

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Overview

Organization

In vitro self-assembly

Mechanism of force generation

Actin in cells

Associated proteins

Actin acts as a track for myosin motor motility

A proposed model – actoclampins track filament ends

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Map overview Semantic statistics

Actin filament

Nodes100
Edges99
Triples51
Avg. degree1.98
Density0.02
Components1

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Actin filament

Top relations

related to In vitro self-assembly · 15
Actin filament → ATP, ATP-bound, Each, Electron, Evidence, F-actin, G-actin, II, In, Measuring, Much, S1, The, They, This
related to Associated proteins · 14
Actin filament → Actin, Actin-related, ADF/cofilin, Arp2/3, CapG, Capping Protein, Filament, Filament-nucleator, Filament-severing, Formins, In, N-WASP, Their, VASP
related to A proposed model – actoclampins track filament ends · 9
Actin filament → Actoclampins, An, Listeria, One, Rickettsia, Shigella, The, Vaccinia, When
related to Organization · 4
Actin filament → Actin, Bundles, Cross-linking, These
related to Actin acts as a track for myosin motor motility · 3
Actin filament → ATP-dependent, Myosin, Various

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Important terminology

actin filament motors proteins atp protein filaments needed cell motility citation end cells actoclampins complex molecular end-tracking microfilaments profilin myosin

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CapZ prevent the addition or loss of monomers at the filament end where actin turnover is unfavorableinstance ofEnd-capping proteins0.80text
such as in the muscle apparatus.Actin polymerization together with capping proteins were recently used to control the 3-dimensional growth of protein filament so as to perform 3D topologies useful in technologyinstance ofEnd-capping proteins0.80text
the making of electrical interconnectinstance ofEnd-capping proteins0.80text
Capping Proteininstance ofActin monomer-binding proteins profilin and thymosin β4Filament barbed-end cappers0.80text
CapGinstance ofActin monomer-binding proteins profilin and thymosin β4Filament barbed-end cappers0.80text
etc.Filament-severing proteins like gelsolin.Actin depolymerizing proteins such as ADF/cofilin.The actin filament network in non-muscle cells is highly dynamicinstance ofActin monomer-binding proteins profilin and thymosin β4Filament barbed-end cappers0.80text
Actin filamentrelated to A proposed model – actoclampins track filament endsOne0.60section
Actin filamentrelated to A proposed model – actoclampins track filament endsThe0.60section
Actin filamentrelated to A proposed model – actoclampins track filament endsActoclampins0.60section
Actin filamentrelated to A proposed model – actoclampins track filament endsListeria0.60section
Actin filamentrelated to A proposed model – actoclampins track filament endsShigella0.60section
Actin filamentrelated to A proposed model – actoclampins track filament endsVaccinia0.60section

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