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Nebulin is an actin-binding protein which is localized to the thin filament of the sarcomeres in skeletal muscle. Nebulin in humans is coded for by the gene NEB. It is a very large protein (600–900 kDa) and binds as many as 200 actin monomers. Because its length is proportional to thin filament length, it is believed that nebulin acts as a thin filament…
The analysis highlights Overview, Knockout phenotype and Structure as prominent areas in the source structure around Nebulin.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Nebulin shows recurring relationship patterns in the source. For example, Nebulin → biceps brachii, deltoid muscle, gastrocnemius muscle, glutes, knee joint, medial head of gastrocnemius muscle, muscle of thigh, quadriceps femoris muscle, skeletal muscle tissue, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, temporal muscle, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle Another extracted example is Nebulin → actin binding, actin cytoskeleton, actin filament binding, cardiac muscle thin filament assembly, cytoplasm, cytoskeleton, cytosol, extracellular exosome, muscle filament sliding, muscle organ development, protein binding, regulation of actin filament length, sarcomere, somatic muscle development, structural constituent of muscle, Z discdkac. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
protein bp human thin filament chr band gene chromosome neb length muscle sarcomere structure mouse function location mice nemaline myopathy
TTTA extracted 96 structured relationships around Nebulin. Examples in this analysis include Nebulin → Aliases → NEB, nebulin, NEB177D, NEM2, AMC6 and Nebulin → Available structures → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1NEB, 1ARK. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Nebulin | Aliases | NEB, nebulin, NEB177D, NEM2, AMC6 | 1.00 | infobox |
| Nebulin | Available structures | Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1NEB, 1ARK | 1.00 | infobox |
| Nebulin | Band | 2q23.3 | 1.00 | infobox |
| Nebulin | Band | 2 C1.1|2 29.98 cM | 1.00 | infobox |
| Nebulin | Bgee | glutes | 1.00 | infobox |
| Nebulin | Bgee | biceps brachii | 1.00 | infobox |
| Nebulin | Bgee | Skeletal muscle tissue of biceps brachii | 1.00 | infobox |
| Nebulin | Bgee | tibialis anterior muscle | 1.00 | infobox |
| Nebulin | Bgee | Skeletal muscle tissue of rectus abdominis | 1.00 | infobox |
| Nebulin | Bgee | gastrocnemius muscle | 1.00 | infobox |
| Nebulin | Bgee | deltoid muscle | 1.00 | infobox |
| Nebulin | Bgee | triceps brachii muscle | 1.00 | infobox |
| Nebulin | Bgee | quadriceps femoris muscle | 1.00 | infobox |
| Nebulin | Bgee | vastus lateralis muscle | 1.00 | infobox |
| Nebulin | Bgee | muscle of thigh | 1.00 | infobox |
| Nebulin | Bgee | knee joint | 1.00 | infobox |
| Nebulin | Bgee | soleus muscle | 1.00 | infobox |
| Nebulin | Bgee | medial head of gastrocnemius muscle | 1.00 | infobox |
| Nebulin | Bgee | skeletal muscle tissue | 1.00 | infobox |
| Nebulin | Bgee | temporal muscle | 1.00 | infobox |
| Nebulin | BioGPS | n/a | 1.00 | infobox |
| Nebulin | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| Nebulin | Chr. | Chromosome 2 (mouse) | 1.00 | infobox |
| Nebulin | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Nebulin | End | 151,734,487 bp | 1.00 | infobox |
| Nebulin | End | 52,378,474 bp | 1.00 | infobox |
| Nebulin | Ensembl | ENSG00000183091 | 1.00 | infobox |
| Nebulin | Entrez | 4703 | 1.00 | infobox |
| Nebulin | External IDs | OMIM: 161650; MGI: 97292; GeneCards: NEB | 1.00 | infobox |
| Nebulin | Gene location (Human) | Gene location (Human)Chr.Chromosome 2 (human)Band2q23.3Start151,485,336 bpEnd151,734,487 bp | 1.00 | infobox |
The concept neighborhoods around Nebulin bring nearby vocabulary together. In this analysis, examples include Structure, Protein and Muscle. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Nebulin, one of the stronger structural bridges in this analysis connects Nebulin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Nebulin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Knockout phenotype & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Nebulin · EN edition · Analysis: TopicsToTalkAbout