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Protein splicing is an intramolecular reaction of a particular protein in which an internal protein segment (called an intein) is removed from a precursor protein with a ligation of C-terminal and N-terminal external proteins (called exteins) on both sides. The splicing junction of the precursor protein is mainly a cysteine or a serine, which are amino…
The analysis highlights History, Technology, Applications and Art as prominent areas in the source structure around Protein splicing.
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The extracted context around Protein splicing shows recurring relationship patterns in the source. For example, Protein splicing → Anraku, ATPase, C-termini, DNA, Hirata, HO, Neurospora, Protein, Saccharomyces, Since, Stevens, VMA1 Another extracted example is Protein splicing → AAs, Inteins, NMR, Pharmaceutical. Use these groups to spot repeated connection types before inspecting the individual relationships.
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protein intein inteins splicing proteins found c-extein gene residue also n-extein precursor example peptide intein-containing class used called side chain
TTTA extracted 23 structured relationships around Protein splicing. Examples in this analysis include Protein splicing → is a → intramolecular reaction of a particular protein in which an internal protein segment and adenosine triphosphate → instance of → The protein splicing reactions which are known now do not require exogenous cofactors or energy sources. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Protein splicing | is a | intramolecular reaction of a particular protein in which an internal protein segment | 0.90 | text |
| adenosine triphosphate | instance of | The protein splicing reactions which are known now do not require exogenous cofactors or energy sources | 0.80 | text |
| protein semisynthesis | instance of | Inteins have been engineered for particular applications | 0.80 | text |
| the selective labeling of protein segments | instance of | Inteins have been engineered for particular applications | 0.80 | text |
| which is useful for NMR studies of large proteins.Pharmaceutical inhibition of intein excision may be a useful tool for drug development | instance of | Inteins have been engineered for particular applications | 0.80 | text |
| Protein splicing | has application | Inteins | 0.60 | section |
| Protein splicing | has application | AAs | 0.60 | section |
| Protein splicing | has application | NMR | 0.60 | section |
| Protein splicing | has application | Pharmaceutical | 0.60 | section |
| Protein splicing | related to history | Neurospora | 0.60 | section |
| Protein splicing | related to history | ATPase | 0.60 | section |
| Protein splicing | related to history | Hirata | 0.60 | section |
The concept neighborhoods around Protein splicing bring nearby vocabulary together. In this analysis, examples include Intein, Splicing and Precursor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Protein splicing, one of the stronger structural bridges in this analysis connects Protein splicing with History. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Protein splicing to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Technology, Applications & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Protein splicing · EN edition · Analysis: TopicsToTalkAbout