Clusterin

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Function

Heat shock protein Molecular chaperone Intracellular ATP Lipid

23 related topics

Clinical significance

Genome-wide association studies Single-nucleotide polymorphism Alzheimer's disease Huntington disease Outer mitochondrial membrane

27 related topics

Structure

Exons

1 related topics

Overview

Protein Gene Molecular chaperone Diseases Neurodegenerative diseases

8 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: CLU, AAG4, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2, clusterin
Band: 8p21.1 · 14 D1|14 34.36 cM
Bgee: external globus pallidus · Achilles tendon · paraflocculus of cerebellum · palpebral conjunctiva · optic nerve
BioGPS: n/a
Chr.: Chromosome 8 (human) · Chromosome 14 (mouse)
Databases: NCBI: entry; OMA: entry

Topics to explore

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Advanced semantic analysis

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Map overview Semantic statistics

Nodes64

Edges63

Triples152

Avg. degree1.97

Density0.03125

Components1

How this topic connects Entity context

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Clusterin

Top relations

Gene ontology · 67

Clusterin → antimicrobial humoral response, apical dendrite, apoptotic process, ATPase activity, blood microparticle, cell death, cell morphogenesis, cell surface, central nervous system myelin maintenance, chaperone binding, chaperone-mediated protein complex assembly, chaperone-mediated protein folding, chromaffin granule, complement activation, complement activation, classical pathway, cytoplasm, cytoplasmic vesicle, cytosol, endoplasmic reticulum, extracellular exosome

Bgee · 20

Clusterin → Achilles tendon, Brodmann area 10, Brodmann area 9, ciliary body, dorsal tegmental nucleus, dorsomedial hypothalamic nucleus, Epithelium of choroid plexus, epithelium of lens, external globus pallidus, habenula, iris, middle frontal gyrus, optic nerve, palpebral conjunctiva, paraflocculus of cerebellum, paraventricular nucleus of hypothalamus, right testis, right uterine tube, subiculum, ventral tegmental area

RNA expression pattern · 20

related to Function · 13

Clusterin → ATP-independent, BAX, Bcl-2, CLU, ER/Golgi, ERK, Meanwhile, NF-κB, Overexpression, Sertoli, The, Unlike, Within

related to Alzheimer's disease · 6

Clusterin → Alzheimer's, CLU, However, SNP, Subsequent, Two

related to External links · 5

Clusterin → Apolipoproteins, Applied Research, Medicine Medical Subject Headings, MeSH, National Library

Band · 2

Clusterin → 14 D1|14 34.36 cM, 8p21.1

Chr. · 2

Clusterin → Chromosome 14 (mouse), Chromosome 8 (human)

End · 2

Clusterin → 27,614,700 bp, 66,218,996 bp

Aliases · 1

Clusterin → CLU, AAG4, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2, clusterin

Important terminology Word statistics

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Important terminology

clu gene protein cancer prostate cell tumor human bp chromosome chr band proteins expression role including disease mrna molecular chaperone

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Clusterin	Aliases	CLU, AAG4, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2, clusterin	1.00	infobox
Clusterin	Band	8p21.1	1.00	infobox
Clusterin	Band	14 D1\|14 34.36 cM	1.00	infobox
Clusterin	Bgee	external globus pallidus	1.00	infobox
Clusterin	Bgee	Achilles tendon	1.00	infobox
Clusterin	Bgee	paraflocculus of cerebellum	1.00	infobox
Clusterin	Bgee	palpebral conjunctiva	1.00	infobox
Clusterin	Bgee	optic nerve	1.00	infobox
Clusterin	Bgee	Brodmann area 10	1.00	infobox
Clusterin	Bgee	right uterine tube	1.00	infobox
Clusterin	Bgee	middle frontal gyrus	1.00	infobox
Clusterin	Bgee	Brodmann area 9	1.00	infobox
Clusterin	Bgee	right testis	1.00	infobox
Clusterin	Bgee	iris	1.00	infobox
Clusterin	Bgee	ciliary body	1.00	infobox
Clusterin	Bgee	epithelium of lens	1.00	infobox
Clusterin	Bgee	habenula	1.00	infobox
Clusterin	Bgee	paraventricular nucleus of hypothalamus	1.00	infobox
Clusterin	Bgee	dorsomedial hypothalamic nucleus	1.00	infobox
Clusterin	Bgee	Epithelium of choroid plexus	1.00	infobox
Clusterin	Bgee	dorsal tegmental nucleus	1.00	infobox
Clusterin	Bgee	subiculum	1.00	infobox
Clusterin	Bgee	ventral tegmental area	1.00	infobox
Clusterin	BioGPS	n/a	1.00	infobox
Clusterin	Chr.	Chromosome 8 (human)	1.00	infobox
Clusterin	Chr.	Chromosome 14 (mouse)	1.00	infobox
Clusterin	Databases	NCBI: entry; OMA: entry	1.00	infobox
Clusterin	End	27,614,700 bp	1.00	infobox
Clusterin	End	66,218,996 bp	1.00	infobox
Clusterin	Ensembl	ENSG00000120885	1.00	infobox

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