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Gp41

Gp41 also known as glycoprotein 41 is a subunit of the envelope protein complex of retroviruses, including human immunodeficiency virus (HIV). Gp41 is a transmembrane protein that contains several sites within its ectodomain that are required for infection of host cells. As a result of its importance in host cell infection, it has also received much…

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Explore the main themes, entities and connections around Gp41. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

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AlphaFold
IPR000328 · PF00517
Available protein structures:
IPR000328 · PF00517
InterPro
IPR000328
PDB
IPR000328 PF00517 (ECOD; PDBsum)
Pfam
PF00517
SCOP2
2siv / SCOPe / SUPFAM

Topics to explore

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Overview

Gene and post-translational modifications

Structure

Function

As a drug target

Advanced semantic analysis

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Map overview Semantic statistics

Gp41

Nodes43
Edges42
Triples58
Avg. degree1.95
Density0.046512
Components1

How this topic connects Entity context

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Gp41

Top relations

related to Function · 13
Gp41 → As, CCR5, CD4, CHR, CXCR4, Furthermore, Gp120, Helper, In, NHRs, The, These, This
related to Structure · 11
Gp41 → C-terminal, CHR, HIV, In, MPER, N-terminal, NHR, The, These, This, While
related to As a drug target · 8
Gp41 → Certain, Enfuviritide, Enfuvirtide, HIV, HIV-1, In, T-20, The
related to External links · 8
Gp41 → Envelope Protein, HIV, HIV Envelope Glycoprotein, Medicine Medical Subject Headings, MeSH, Month, National Library, PDB Molecule
related to Gene and post-translational modifications · 5
Gp41 → Gp160, HIV, In, Once, The
AlphaFold · 2
Gp41 → IPR000328, PF00517
Available protein structures: · 2
Gp41 → IPR000328, PF00517
is a · 2
Gp41 → transmembrane portion of the spike protein complex with a portion of the glycoprotein buried within the viral envelope at all times.Gp41 has three prominent regions within the s…, transmembrane protein that contains several sites within its ectodomain that are required for infection of host cells
InterPro · 1
Gp41 → IPR000328
PDB · 1
Gp41 → IPR000328 PF00517 (ECOD; PDBsum)

Important terminology Word statistics

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Important terminology

also gp120 fusion target hiv structure envelope host protein peptides conformational cell potential glycoprotein region complex within infection transmembrane ectodomain

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Gp41AlphaFoldIPR0003281.00infobox
Gp41AlphaFoldPF005171.00infobox
Gp41Available protein structures:IPR0003281.00infobox
Gp41Available protein structures:PF005171.00infobox
Gp41InterProIPR0003281.00infobox
Gp41PDBIPR000328 PF00517 (ECOD; PDBsum)1.00infobox
Gp41PfamPF005171.00infobox
Gp41SCOP22siv / SCOPe / SUPFAM1.00infobox
Gp41SymbolGP411.00infobox
Gp41is atransmembrane protein that contains several sites within its ectodomain that are required for infection of host cells0.90text
Gp41is atransmembrane portion of the spike protein complex with a portion of the glycoprotein buried within the viral envelope at all times.Gp41 has three prominent regions within the s…0.90text
Helper T cellsinstance offound on susceptible cells0.80text

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