Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

CD16

CD16, also known as FcγRIII, is a cluster of differentiation molecule found on the surface of natural killer cells, neutrophils, monocytes, macrophages, and certain T cells. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), which participate in signal transduction. The most well-researched membrane receptor implicated in…

Art, As a drug target & Clinical significance

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around CD16. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Alt. symbols
FCGR3, FCG3
Domains
InterPro
HGNC
3619
Locus
Chr. 1 q23
NCBI gene
2214
OMIM
146740

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Function

Mechanism and regulation

Clinical significance

As a drug target

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

CD16

Nodes52
Edges51
Triples82
Avg. degree1.96
Density0.038462
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

CD16

Top relations

related to Mechanism and regulation · 16
CD16 → ADCC, After, CD25, CsA, CsA-sensitive, Fc, IFN-gamma, IgG, IL-2-R, In, NFATp, NK, The, These, This CD16-induced, TNF
related to As a drug target · 15
CD16 → Anti-CD19/CD16, B-cell, Bispecific, CD16A, CD16B, CD19/CD16, FasL, Fc-optimized, FcγRIV, Furthermore, HER2, In, Margetuximab, TRAIL, With
related to Structure · 13
CD16 → C-terminal Ig, Fc, FcγRIIa, FcγRIIb, FcγRIII, FcγRIIIb, FcεRIα, Ig, Ig-like, In, Specifically, The, These
related to Function · 9
CD16 → CD16a, CD16b, Fc, FcγRIIIa, FcγRIIIb, GPI, III Fcγ, In, While FcγRIIIa
related to Clinical significance · 7
CD16 → ADCC, After, CD38, FcγRIII, However, In, NK
related to External links · 4
CD16 → Antigens, Medicine Medical Subject Headings, MeSH, National Library
is a · 2
CD16 → molecule of the immunoglobulin superfamily, type III Fcγ receptor
Alt. symbols · 1
CD16 → FCGR3, FCG3
Domains · 1
CD16 → InterPro
HGNC · 1
CD16 → 3619

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cells nk cell neutrophils monocytes fcγriiib receptor antibodies human expression also fc cytotoxicity adcc fcγriiia degranulation addition cancer natural killer

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CD16Alt. symbolsFCGR3, FCG31.00infobox
CD16DomainsInterPro1.00infobox
CD16HGNC36191.00infobox
CD16LocusChr. 1 q231.00infobox
CD16NCBI gene22141.00infobox
CD16OMIM1467401.00infobox
CD16RefSeqNM_0005691.00infobox
CD16Search forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
CD16StructuresSwiss-model1.00infobox
CD16SymbolFCGR3A1.00infobox
CD16UniProtP086371.00infobox
CD16is amolecule of the immunoglobulin superfamily0.90text
CD16is atype III Fcγ receptor0.90text

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.