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DLG1

Discs large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a scaffold protein that in humans is encoded by the SAP97 gene.

Structure, Function & Clinical significance

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Structure

7 related topics

Function

6 related topics

Clinical significance

1 related topics

Overview

9 related topics

Key facts & relationships

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Aliases
DLG1, DLGH1, SAP-97, SAP97, dJ1061C18.1.1, hdlg, B130052P05Rik, E-dlg/SAP97, mKIAA4187, discs large homolog 1, scribble cell polarity complex component, discs large MAGUK scaffo…
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1PDR, 2M3M, 2OQS, 2X7Z, 3RL7, 3RL8, 3W9Y, 4AMH, 4G69
Band
3q29 · 16 B2|16 22.4 cM
Bgee
endothelial cell · corpus callosum · dorsal motor nucleus of vagus nerve · inferior olivary nucleus · inferior ganglion of vagus nerve
BioGPS
More reference expression data
Chr.
Chromosome 3 (human) · Chromosome 16 (mouse)

Topics to explore

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Overview

Function

Clinical significance

Structure

Advanced semantic analysis

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Map overview Semantic statistics

DLG1

Nodes28
Edges27
Triples179
Avg. degree1.93
Density0.071429
Components1

How this topic connects Entity context

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DLG1

Top relations

Gene ontology · 114
DLG1 → actin filament organization, activation of protein kinase activity, amyloid precursor protein metabolic process, apical plasma membrane, astral microtubule organization, basement membrane, basolateral plasma membrane, bicellular tight junction, bicellular tight junction assembly, branching involved in ureteric bud morphogenesis, cadherin binding, cell junction, cell projection membrane, cell-cell adhesion, cell-cell junction, chemical synaptic transmission, cortical actin cytoskeleton organization, cortical microtubule organization, cytoplasm, cytoplasmic side of plasma membrane
Bgee · 20
DLG1 → Brodmann area 23, condyle, conjunctival fornix, corpus callosum, dorsal motor nucleus of vagus nerve, endothelial cell, epithelium of colon, external globus pallidus, globus pallidus, hair follicle, inferior ganglion of vagus nerve, inferior olivary nucleus, medullary collecting duct, olfactory tubercle, Paneth cell, primary motor cortex, subthalamic nucleus, tail of embryo, utricle, vestibular membrane of cochlear duct
RNA expression pattern · 20
DLG1 → Brodmann area 23, condyle, conjunctival fornix, corpus callosum, dorsal motor nucleus of vagus nerve, endothelial cell, epithelium of colon, external globus pallidus, globus pallidus, hair follicle, inferior ganglion of vagus nerve, inferior olivary nucleus, medullary collecting duct, olfactory tubercle, Paneth cell, primary motor cortex, subthalamic nucleus, tail of embryo, utricle, vestibular membrane of cochlear duct
Band · 2
DLG1 → 16 B2|16 22.4 cM, 3q29
Chr. · 2
DLG1 → Chromosome 16 (mouse), Chromosome 3 (human)
End · 2
DLG1 → 197,299,330 bp, 31,693,947 bp
related to Clinical significance · 2
DLG1 → Crohn's, Mutations
Aliases · 1
DLG1 → DLG1, DLGH1, SAP-97, SAP97, dJ1061C18.1.1, hdlg, B130052P05Rik, E-dlg/SAP97, mKIAA4187, discs large homolog 1, scribble cell polarity complex component, discs large MAGUK scaffo…
Available structures · 1
DLG1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1PDR, 2M3M, 2OQS, 2X7Z, 3RL7, 3RL8, 3W9Y, 4AMH, 4G69
BioGPS · 1
DLG1 → More reference expression data

Important terminology Word statistics

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Important terminology

sap97 gene human protein bp domain chr band function involved sap97's chromosome synaptic epithelial membrane external discs large expressed plasma

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DLG1AliasesDLG1, DLGH1, SAP-97, SAP97, dJ1061C18.1.1, hdlg, B130052P05Rik, E-dlg/SAP97, mKIAA4187, discs large homolog 1, scribble cell polarity complex component, discs large MAGUK scaffo…1.00infobox
DLG1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1PDR, 2M3M, 2OQS, 2X7Z, 3RL7, 3RL8, 3W9Y, 4AMH, 4G691.00infobox
DLG1Band3q291.00infobox
DLG1Band16 B2|16 22.4 cM1.00infobox
DLG1Bgeeendothelial cell1.00infobox
DLG1Bgeecorpus callosum1.00infobox
DLG1Bgeedorsal motor nucleus of vagus nerve1.00infobox
DLG1Bgeeinferior olivary nucleus1.00infobox
DLG1Bgeeinferior ganglion of vagus nerve1.00infobox
DLG1Bgeesubthalamic nucleus1.00infobox
DLG1Bgeeepithelium of colon1.00infobox
DLG1Bgeehair follicle1.00infobox
DLG1Bgeeexternal globus pallidus1.00infobox
DLG1BgeeBrodmann area 231.00infobox
DLG1Bgeetail of embryo1.00infobox
DLG1Bgeeglobus pallidus1.00infobox
DLG1Bgeemedullary collecting duct1.00infobox
DLG1Bgeevestibular membrane of cochlear duct1.00infobox
DLG1Bgeeprimary motor cortex1.00infobox
DLG1Bgeeconjunctival fornix1.00infobox
DLG1Bgeeolfactory tubercle1.00infobox
DLG1BgeePaneth cell1.00infobox
DLG1Bgeeutricle1.00infobox
DLG1Bgeecondyle1.00infobox
DLG1BioGPSMore reference expression data1.00infobox
DLG1Chr.Chromosome 3 (human)1.00infobox
DLG1Chr.Chromosome 16 (mouse)1.00infobox
DLG1DatabasesNCBI: entry; OMA: entry1.00infobox
DLG1End197,299,330 bp1.00infobox
DLG1End31,693,947 bp1.00infobox

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