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APBA1: Function, Interactions & Overview

Amyloid beta A4 precursor protein-binding family A member 1 is a protein that in humans is encoded by the APBA1 gene.

Language: English [EN]
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APBA1 topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around APBA1.

Related topics
13
Source areas
3
Connected nodes
16
Extracted relationships
98
Related term clusters
9
Bridge connections
16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 7 topics
Interactions · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
APBA1, D9S411E, LIN10, MINT1, X11, X11A, X11ALPHA, amyloid beta precursor protein binding family A member 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AQC, 1U37, 1U38, 1U39, 1U3B, 1X11, 1X45, 1Y7N
Band
9q21.12 · 19|19 B
Bgee
superior frontal gyrus · prefrontal cortex · right frontal lobe · temporal lobe · amygdala
BioGPS
More reference expression data
Chr.
Chromosome 9 (human) · Chromosome 19 (mouse)

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How APBA1 connects Entity context

The extracted context around APBA1 shows recurring relationship patterns in the source. For example, APBA1 → amyloid-beta binding, axo-dendritic transport, cell adhesion, chemical synaptic transmission, cytoplasm, cytosol, dendritic spine, gamma-aminobutyric acid secretion, glutamate secretion, glutamatergic synapse, Golgi apparatus, in utero embryonic development, intracellular protein transport, locomotory behavior, membrane, multicellular organism growth, nervous system development, neuron projection, neurotransmitter secretion, nucleus Another extracted example is APBA1 → amygdala, anterior cingulate cortex, Brodmann area 9, central gray substance of midbrain, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, habenula, hypothalamus, inferior colliculi, medial dorsal nucleus, nucleus accumbens, pontine nuclei, prefrontal cortex, primary visual cortex, right frontal lobe, subiculum, superior frontal gyrus, temporal lobe, ventral tegmental area, visual cortex. Use these groups to spot repeated connection types before inspecting the individual relationships.

APBA1

Top relations

Gene ontology · 31
APBA1 → amyloid-beta binding, axo-dendritic transport, cell adhesion, chemical synaptic transmission, cytoplasm, cytosol, dendritic spine, gamma-aminobutyric acid secretion, glutamate secretion, glutamatergic synapse, Golgi apparatus, in utero embryonic development, intracellular protein transport, locomotory behavior, membrane, multicellular organism growth, nervous system development, neuron projection, neurotransmitter secretion, nucleus
Bgee · 20
APBA1 → amygdala, anterior cingulate cortex, Brodmann area 9, central gray substance of midbrain, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, habenula, hypothalamus, inferior colliculi, medial dorsal nucleus, nucleus accumbens, pontine nuclei, prefrontal cortex, primary visual cortex, right frontal lobe, subiculum, superior frontal gyrus, temporal lobe, ventral tegmental area, visual cortex
RNA expression pattern · 20
APBA1 → amygdala, anterior cingulate cortex, Brodmann area 9, central gray substance of midbrain, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, habenula, hypothalamus, inferior colliculi, medial dorsal nucleus, nucleus accumbens, pontine nuclei, prefrontal cortex, primary visual cortex, right frontal lobe, subiculum, superior frontal gyrus, temporal lobe, ventral tegmental area, visual cortex
related to Interactions · 4
APBA1 → Amyloid, CASK, CCS, KCNJ12
Band · 2
APBA1 → 19|19 B, 9q21.12
Chr. · 2
APBA1 → Chromosome 19 (mouse), Chromosome 9 (human)
End · 2
APBA1 → 23,926,960 bp, 69,672,371 bp
Aliases · 1
APBA1 → APBA1, D9S411E, LIN10, MINT1, X11, X11A, X11ALPHA, amyloid beta precursor protein binding family A member 1
Available structures · 1
APBA1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AQC, 1U37, 1U38, 1U39, 1U3B, 1X11, 1X45, 1Y7N
BioGPS · 1
APBA1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene protein bp human chr band precursor chromosome amyloid family member location beta mouse function external pdb uniprot q02410 a4

APBA1 relationships Subject–Predicate–Object triples

TTTA extracted 98 structured relationships around APBA1. Examples in this analysis include APBA1 → Aliases → APBA1, D9S411E, LIN10, MINT1, X11, X11A, X11ALPHA, amyloid beta precursor protein binding family A member 1 and APBA1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AQC, 1U37, 1U38, 1U39, 1U3B, 1X11, 1X45, 1Y7N. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
APBA1AliasesAPBA1, D9S411E, LIN10, MINT1, X11, X11A, X11ALPHA, amyloid beta precursor protein binding family A member 11.00infobox
APBA1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AQC, 1U37, 1U38, 1U39, 1U3B, 1X11, 1X45, 1Y7N1.00infobox
APBA1Band9q21.121.00infobox
APBA1Band19|19 B1.00infobox
APBA1Bgeesuperior frontal gyrus1.00infobox
APBA1Bgeeprefrontal cortex1.00infobox
APBA1Bgeeright frontal lobe1.00infobox
APBA1Bgeetemporal lobe1.00infobox
APBA1Bgeeamygdala1.00infobox
APBA1Bgeeanterior cingulate cortex1.00infobox
APBA1Bgeedorsolateral prefrontal cortex1.00infobox
APBA1Bgeehypothalamus1.00infobox
APBA1BgeeBrodmann area 91.00infobox
APBA1Bgeenucleus accumbens1.00infobox
APBA1Bgeehabenula1.00infobox
APBA1Bgeeventral tegmental area1.00infobox
APBA1Bgeevisual cortex1.00infobox
APBA1Bgeeprimary visual cortex1.00infobox
APBA1Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
APBA1Bgeepontine nuclei1.00infobox
APBA1Bgeeinferior colliculi1.00infobox
APBA1Bgeecentral gray substance of midbrain1.00infobox
APBA1Bgeemedial dorsal nucleus1.00infobox
APBA1Bgeesubiculum1.00infobox
APBA1BioGPSMore reference expression data1.00infobox
APBA1Chr.Chromosome 9 (human)1.00infobox
APBA1Chr.Chromosome 19 (mouse)1.00infobox
APBA1DatabasesNCBI: entry; OMA: entry1.00infobox
APBA1End69,672,371 bp1.00infobox
APBA1End23,926,960 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around APBA1 bring nearby vocabulary together. In this analysis, examples include Gene, Protein and Family. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • APBA1
    • Gene
    • Protein
    • Family
    • Location
    • Member
    • Human
    • Precursor
    • Binding
    • Encoded
    • Function
    • Search
    • X11
  • apba1
    • Gene
    • Protein
    • Family
    • Location
    • Member
    • Human
    • Precursor
    • Binding
    • Encoded
    • Function
    • Search
    • X11
  • protein
    • Adhesion
    • Binding
    • Cell
    • Exocytosis
    • Function
    • Search
    • Synaptic
    • Vesicle
    • X11
    • Chromosome
    • Location
    • Bp
  • gene
    • Location
    • Human
    • Chromosome
    • Member
    • Bp
    • Chr
    • Binding
    • End
    • Function
    • Mouse
    • Protein
    • Search
  • amyloid precursor protein
    • Precursor
    • Protein
    • Apba1
    • Family
    • Member
    • Available
    • Beta
    • Pdb
    • Protein-binding
    • Adhesion
    • Binding
    • Cell
  • function
    • Binding
    • Search
    • X11
    • Chromosome
    • Location
    • Member
    • Bp
    • Chr
    • Human
    • Adhesion
    • Amyloid-beta
    • Available
  • a beta peptide
    • Family
    • Member
    • Apba1
    • External
    • Precursor
    • Gene
    • Protein
    • Available
    • Binding
    • Encoded
    • Function
    • Pdb
  • exocytosis
    • Synaptic
    • Vesicle
    • Function
    • Mouse
    • Protein
    • Q02410
    • Search
    • Uniprot
    • X11
    • Family
    • Location
    • Member

Connections between topic areas Semantic bridges

For APBA1, one of the stronger structural bridges in this analysis connects APBA1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
APBA1 — Function · splits 9 ⟂ 8
APBA1 — Interactions · splits 12 ⟂ 5
APBA1 — Overview · splits 14 ⟂ 3

Map overview Semantic statistics

APBA1

Nodes17
Edges16
Triples98
Avg. degree1.88
Density0.117647
Components1

Source & methodology

TTTA analyzes the structure around APBA1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — APBA1 · EN edition · Analysis: TopicsToTalkAbout

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