ARNTL2

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History

John B. Hogenesch PAS domain Eukaryotic CLOCK Hypoxia-inducible factors

7 related topics

Species distribution

Chimpanzees Rats Zebrafish Diverged Amino acids

5 related topics

Structure

Helix-loop-helix N-terminal C-terminus Aryl hydrocarbon receptor

4 related topics

Knockout Studies

Per1 Cry1 Cry2 Promoter

4 related topics

Key facts & relationships

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Aliases: ARNTL2, BMAL2, CLIF, MOP9, PASD9, bHLHe6, aryl hydrocarbon receptor nuclear translocator like 2
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KDK
Band: 12p11.23 · 6|6 G3
Bgee: amniotic fluid · oral cavity · buccal mucosa cell · islet of Langerhans · mucosa of pharynx
BioGPS: More reference expression data
Chr.: Chromosome 12 (human) · Chromosome 6 (mouse)

Topics to explore

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Function

Per2
Knockout Knockout mouse

Species distribution

Chimpanzees Chimpanzee
Rats Rat
Zebrafish
Diverged Genetic divergence
Amino acids Amino acid

Knockout Studies

Per1
Cry1
Cry2
Promoter Promoter (genetics)

Advanced semantic analysis

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Map overview Semantic statistics

Nodes42

Edges41

Triples133

Avg. degree1.95

Density0.047619

Components1

How this topic connects Entity context

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ARNTL2

Top relations

related to history · 23

ARNTL2 → ARNTL, ARNTL/MOP3, BMAL1, BMAL1-CLOCK, BMAL2, BMAL2-CLOCK, CLOCK, CYCLE, Due, Further, HIF1α, Hogenesch, Hogenesch’s, John, Knockout, Like ARNTL/BMAL1, MOP3, MOP4, MOP9, PAS

Bgee · 20

ARNTL2 → amniotic fluid, buccal mucosa cell, cumulus cell, esophagus, female urethra, gonad, gums, islet of Langerhans, lens, lip, mucosa of pharynx, oral cavity, primary oocyte, primary visual cortex, secondary oocyte, stromal cell of endometrium, superior frontal gyrus, testicle, vagina, zygote

Gene ontology · 20

ARNTL2 → circadian rhythm, cytoplasm, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, E-box binding, entrainment of circadian clock, nucleolus, nucleus, positive regulation of circadian rhythm, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein dimerization activity, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, rhythmic process, RNA polymerase II cis-regulatory region sequence-specific DNA binding, transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding, transcription regulator complex, transcription, DNA-templated

RNA expression pattern · 20

related to External links · 11

ARNTL2 → Aryl, Human ARNTL2, Medicine Medical Subject Headings, MeSH, National Library, Overview, PDB, PDBe-KB, Q8WYA1, UCSC Genome Browser, UniProt

related to Species distribution · 6

ARNTL2 → ARNTL, BMAL1, BMAL2, Human, Identifying, Orthologs

Band · 2

ARNTL2 → 12p11.23, 6|6 G3

Chr. · 2

ARNTL2 → Chromosome 12 (human), Chromosome 6 (mouse)

End · 2

ARNTL2 → 146,735,027 bp, 27,425,289 bp

is a · 2

ARNTL2 → candidate gene for human type 1 diabetes.In overexpression studies, paralog to Arntl

Important terminology Word statistics

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Important terminology

bmal2 gene clock circadian bmal1 arntl protein human role also study mop9 function bp expression transcription found mice may studies

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
ARNTL2	Aliases	ARNTL2, BMAL2, CLIF, MOP9, PASD9, bHLHe6, aryl hydrocarbon receptor nuclear translocator like 2	1.00	infobox
ARNTL2	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KDK	1.00	infobox
ARNTL2	Band	12p11.23	1.00	infobox
ARNTL2	Band	6\|6 G3	1.00	infobox
ARNTL2	Bgee	amniotic fluid	1.00	infobox
ARNTL2	Bgee	oral cavity	1.00	infobox
ARNTL2	Bgee	buccal mucosa cell	1.00	infobox
ARNTL2	Bgee	islet of Langerhans	1.00	infobox
ARNTL2	Bgee	mucosa of pharynx	1.00	infobox
ARNTL2	Bgee	gonad	1.00	infobox
ARNTL2	Bgee	testicle	1.00	infobox
ARNTL2	Bgee	gums	1.00	infobox
ARNTL2	Bgee	vagina	1.00	infobox
ARNTL2	Bgee	stromal cell of endometrium	1.00	infobox
ARNTL2	Bgee	zygote	1.00	infobox
ARNTL2	Bgee	secondary oocyte	1.00	infobox
ARNTL2	Bgee	primary oocyte	1.00	infobox
ARNTL2	Bgee	esophagus	1.00	infobox
ARNTL2	Bgee	female urethra	1.00	infobox
ARNTL2	Bgee	primary visual cortex	1.00	infobox
ARNTL2	Bgee	superior frontal gyrus	1.00	infobox
ARNTL2	Bgee	lip	1.00	infobox
ARNTL2	Bgee	cumulus cell	1.00	infobox
ARNTL2	Bgee	lens	1.00	infobox
ARNTL2	BioGPS	More reference expression data	1.00	infobox
ARNTL2	Chr.	Chromosome 12 (human)	1.00	infobox
ARNTL2	Chr.	Chromosome 6 (mouse)	1.00	infobox
ARNTL2	Databases	NCBI: entry; OMA: entry	1.00	infobox
ARNTL2	End	27,425,289 bp	1.00	infobox
ARNTL2	End	146,735,027 bp	1.00	infobox

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