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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. The etymology stems from Latin ligare, which means 'to bind'. In protein-ligand binding, the ligand is usually a molecule which produces a signal by binding to a site on a target protein. The binding typically results in a…

Applications, Receptor/ligand binding affinity & Methods used to study binding

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Receptor/ligand binding affinity

Selective and non-selective

Hydrophobic ligands

  • PIP2 Phosphatidylinositol 4,5-bisphosphate

Bivalent ligand

Methods used to study binding

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Ligand (biochemistry)

Nodes103
Edges102
Triples6
Avg. degree1.98
Density0.019417
Components1

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binding ligand receptor ligands affinity protein target also agonist concentration response bivalent site bind physiological interactions molecule efficacy used biological

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SubjectPredicateObjectConfidenceSrc
fluorescence quenchinginstance ofusing methods0.80text
isothermal titration calorimetry or surface plasmon resonance.Low-affinity bindinginstance ofusing methods0.80text
World Community Gridinstance ofGrid.org has been succeeded by similar projects0.80text
Human Proteome Folding Projectinstance ofGrid.org has been succeeded by similar projects0.80text
Compute Against Cancerinstance ofGrid.org has been succeeded by similar projects0.80text
Foldinginstance ofGrid.org has been succeeded by similar projects0.80text

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