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Alzheimer's disease

Alzheimer's disease (AD) is a neurodegenerative disease and is the most common cause of dementia, accounting for around 60–70% of cases. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of…

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Causes
Poorly understood
Complications
Infections, falls and aspiration pneumonia in the terminal stage
Diagnostic method
Based on symptoms and cognitive testing after ruling out other possible causes
Differential diagnosis
Normal brain aging, Lewy body dementia, Trisomy 21
Duration
Long term
Frequency
50 million (2020)

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Overview

Signs and symptoms

Causes

Pathophysiology

Diagnosis

Prevention

Management

Prognosis

Epidemiology

History

Society and culture

Research

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Map overview Semantic statistics

Alzheimer's disease

Nodes458
Edges457
Triples300
Avg. degree2
Density0.004367
Components1

How this topic connects Entity context

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Alzheimer's disease

Top relations

related to Media · 41
Alzheimer's disease → Alice Munro's, Alzheimer's, American, An Empty Bliss Beyond, Ashita, Away, Barbara, Caretaker, Columbia University, Documentaries, End, English, Everywhere, Her, Hiroshi Ogiwara's, Iris, Iris Murdoch, John Bayley's, Julianne Moore, Kioku
related to history · 20
Alzheimer's disease → Alois Alzheimer, Alzheimer, Alzheimer's, Auguste, During, Emil Kraepelin, Eventually, For, German, Greek, He, It, July, Kraepelin, Psychiatry, Roman, SDAT, Textbook, The, This
related to Diagnosis · 17
Alzheimer's disease → AD, Advanced, Alzheimer's, Atrophy, Because, Brain, CT, Domains, FDA-approved, FDG-PET, MRI, On MRI, PET, SPECT, The, United States, Up
related to Disease mechanism · 15
Alzheimer's disease → Alzheimer's, Alzheimer's-affected, As, Aβ, Ca2, DNA, Evidence, Exactly, However, Iron, Misfolded Aβ, Products, Some, The, Whatever
related to Criteria · 14
Alzheimer's disease → AD, Aging-Alzheimer's Association, Alzheimer's, Diagnostic, DSM, DSM-5, DSM-IV-TR, Eight, International Working Group, Mental Disorders, National Institute, NIA-AA, Statistical Manual, There
related to Middle stage · 14
Alzheimer's disease → Alzheimer's, Approximately, Behavioral, Common, Complex, During, Long-term, Progressive, Reading, Speech, Subjects, Sundowning, These, Urinary
related to Electrophysiology · 13
Alzheimer's disease → Alzheimer's, Creutzfeldt, Despite, EEG, EFNS Quantitative EEG, Electroencephalography, ERP, ERPs, Event-related, Expert, Jakob, Meta-analyses, P300
related to External links · 12
Alzheimer's disease → Alzforum, Alzheimer's, Alzheimer's Disease Brain Cell, Alzheimer's Disease Research Timeline, Apr, Ars Technica, Atlas, For, Gitlin, Jonathan, The Amyloid Mafia, What's
related to Neuropathology · 12
Alzheimer's disease → Although, Alzheimer's, At, Both, In, It, Lewy, MRI, PET, Studies, The, These
related to Epidemiology · 11
Alzheimer's disease → AD, Advancing, Alzheimer's, Both, In, Italy, Prevalence, Regarding, Since, Spain, The

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Important terminology

disease alzheimer's ad cognitive dementia risk people brain may diagnosis also amyloid plaques symptoms impairment associated include tau protein

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Alzheimer's diseaseCausesPoorly understood1.00infobox
Alzheimer's diseaseComplicationsInfections, falls and aspiration pneumonia in the terminal stage1.00infobox
Alzheimer's diseaseDiagnostic methodBased on symptoms and cognitive testing after ruling out other possible causes1.00infobox
Alzheimer's diseaseDifferential diagnosisNormal brain aging, Lewy body dementia, Trisomy 211.00infobox
Alzheimer's diseaseDurationLong term1.00infobox
Alzheimer's diseaseFrequency50 million (2020)1.00infobox
Alzheimer's diseaseMedicationAcetylcholinesterase inhibitors, NMDA receptor antagonists1.00infobox
Alzheimer's diseaseNamed afterAlois Alzheimer1.00infobox
Alzheimer's diseaseOther namesAlzheimer's dementia1.00infobox
Alzheimer's diseasePrognosis100% mortality, life expectancy 3–12 years1.00infobox
Alzheimer's diseasePronunciation/ˈæltshaɪmərz/, .mw-parser-output .IPA-label-small{font-size:85%}.mw-parser-output .references .IPA-label-small,.mw-parser-output .infobox .IPA-label-small,.mw-parser-output .na…1.00infobox
Alzheimer's diseaseRisk factorsGenetics, head injuries, clinical depression, hypertension, psychological stress, lack of physical and mental exercise1.00infobox
Alzheimer's diseaseSpecialtyNeurology1.00infobox
Alzheimer's diseaseSymptomsMemory loss, problems with language, disorientation, mood swings1.00infobox
Alzheimer's diseaseUsual onsetOver 65 years old1.00infobox
Alzheimer's diseaseis aspecific isoform of apolipoprotein E0.90text

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