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Allylestrenol

Allylestrenol, sold under the brand names Gestanin and Turinal among others, is a progestin medication which is used to treat recurrent and threatened miscarriage and to prevent premature labor in pregnant women. However, except in the case of proven progesterone deficiency, its use for such purposes is no longer recommended. A Cochrane review in 2025…

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3D model (JSmol)
Interactive image
ATC code
G03DC01 (WHO)
CAS Number
432-60-0 Y
ChEBI
CHEBI:31189 Y
ChEMBL
ChEMBL2105618 Y
ChemSpider
205855 Y

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Overview

Medical uses

Side effects

Pharmacology

Chemistry

History

Society and culture

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Map overview Semantic statistics

Allylestrenol

Nodes186
Edges185
Triples178
Avg. degree1.99
Density0.010753
Components1

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Allylestrenol

Top relations

related to Brand names · 55
Allylestrenol → Alese, Alilestrenol, Allynol, Allytry, Alynol, Anin, Arandal, Astanol, Cobarenol, Crestanon, Elmolan, Fetugard, Foegard, Fulterm, Gestanin, Gestanol, Gestanon, Gestanyn, Gestin, Geston
related to Availability · 46
Allylestrenol → Africa, Australia, Austria, Bangladesh, Belgium, Brazil, Canada, Czech Republic, Eastern, Egypt, Europe, Germany, Greece, Hong Kong, However, Hungary, India, Indonesia, It, Italy
related to Generic names · 9
Allylestrenol → BANTooltip British Approved Name, DCFTooltip Dénomination Commune Française, DCITTooltip Denominazione Comune Italiana, INNTooltip International Nonproprietary Name, JANTooltip Japanese Accepted Name, Name, SC-6393, The, The BANTooltip British Approved
related to Medical uses · 8
Allylestrenol → BPH, However, In, Japan, On, Related, The, Unlike
has effect · 7
Allylestrenol → BPH, NSAID-precipitated, NSAIDs, Owing, Side, The, When
related to Chemistry · 6
Allylestrenol → AAS, As, C17α, C3, It, This
related to Pharmacokinetics · 6
Allylestrenol → CYP3A4, Following, In, It, SHBG, The
is a · 4
Allylestrenol → C17α allyl and C3 deketo derivative of the AAS nandrolone, derivative of 17α-allyltestosterone rather than of 17α-ethynyltestosterone.Allylestrenol is also unique among most 19-nortestosterone progestins in that it lacks the ketone at t…, far less potent progestogen than many other 19-nortestosterone derivatives, progestin
related to Available forms · 4
Allylestrenol → BPH, In Japan, It, Perselin
related to Synthesis · 3
Allylestrenol → Chemical, Chinese, Prior

Important terminology Word statistics

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Important terminology

used progesterone medication testosterone also bph effects 17α-allyl-19-nortestosterone japan mg found men marketed women affinity progestogen recurrent names treatment levels

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Allylestrenol3D model (JSmol)Interactive image1.00infobox
AllylestrenolATC codeG03DC01 (WHO)1.00infobox
AllylestrenolCAS Number432-60-0 Y1.00infobox
AllylestrenolChEBICHEBI:31189 Y1.00infobox
AllylestrenolChEMBLChEMBL2105618 Y1.00infobox
AllylestrenolChemSpider205855 Y1.00infobox
AllylestrenolCompTox Dashboard (EPA)DTXSID90225741.00infobox
AllylestrenolDrug classProgestogen; Progestin1.00infobox
AllylestrenolDrugBankDB01431 Y1.00infobox
AllylestrenolECHA InfoCard100.006.4401.00infobox
AllylestrenolElimination half-life"Several hours" or 10 hours1.00infobox
AllylestrenolExcretionUrine (as conjugates)1.00infobox
AllylestrenolFormulaC21H32O1.00infobox
AllylestrenolKEGGD01374 Y1.00infobox
AllylestrenolLegal statusIn general: ℞ (Prescription only)1.00infobox
AllylestrenolMetabolismLiver (reduction, hydroxylation, conjugation; CYP3A4)1.00infobox
AllylestrenolMetabolites• 17α-Allyl-19-NTTooltip 17α-Allyl-19-nortestosterone1.00infobox
AllylestrenolMolar mass300.486 g·mol−11.00infobox
AllylestrenolOther namesAllyloestrenol; SC-6393; Org AL-25; 3-Deketo-17α-allyl-19-nortestosterone; 17α-Allylestr-4-en-17β-ol; 17α-(Prop-2-en-1-yl)estr-4-en-17β-ol1.00infobox
AllylestrenolPregnancy categoryUsed in threatened miscarriage and recurrent pregnancy loss1.00infobox
AllylestrenolProtein binding"Considerable" (and low affinity for SHBGTooltip sex hormone-binding globulin)1.00infobox
AllylestrenolPubChem CID2359051.00infobox
AllylestrenolRoutes of administrationBy mouth1.00infobox
AllylestrenolTrade namesGestanin, Gestanon, Perselin, Turinal, others1.00infobox
AllylestrenolUNIII47VB5DZ8O1.00infobox
Allylestrenolis aprogestin0.90text
Allylestrenolis afar less potent progestogen than many other 19-nortestosterone derivatives0.90text
Allylestrenolis aderivative of 17α-allyltestosterone rather than of 17α-ethynyltestosterone.Allylestrenol is also unique among most 19-nortestosterone progestins in that it lacks the ketone at t…0.90text
Allylestrenolis aC17α allyl and C3 deketo derivative of the AAS nandrolone0.90text

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