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ACVR1B: Function, Overview & Interactions

Activin receptor type-1B is a protein that in humans is encoded by the ACVR1B gene.

Language: English [EN]
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ACVR1B topic overview

The analysis highlights Function, Overview and Interactions as prominent areas in the source structure around ACVR1B.

Related topics
17
Source areas
3
Connected nodes
20
Extracted relationships
122
Concept neighborhoods
10
Bridge connections
20

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 12 topics
Function · 4 topics
Interactions · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.30
Aliases
ACVR1B, ACTRIB, ACVRLK4, ALK4, SKR2, activin A receptor type 1B
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3H9R, 3MTF, 3OOM, 3Q4U, 4BGG, 4C02, 4DYM
Band
12q13.13 · 15 F1|15 56.48 cM
Bgee
secondary oocyte · middle temporal gyrus · pancreatic ductal cell · renal medulla · Brodmann area 23
BioGPS
n/a

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ACVR1B connects Entity context

The extracted context around ACVR1B shows recurring relationship patterns in the source. For example, ACVR1B → activin binding, activin receptor activity, type I, activin receptor complex, activin receptor signaling pathway, activin-activated receptor activity, ATP binding, cell surface, central nervous system development, cytosol, development of primary female sexual characteristics, extrinsic apoptotic signaling pathway, G1/S transition of mitotic cell cycle, growth factor binding, hair follicle development, in utero embryonic development, inhibin binding, integral component of membrane, integral component of plasma membrane, kinase activity, membrane Another extracted example is ACVR1B → beta cell, Brodmann area 10, Brodmann area 23, epithelium of stomach, hair follicle, kidney tubule, lateral nuclear group of thalamus, middle temporal gyrus, nucleus accumbens, olfactory tubercle, pancreatic ductal cell, Paneth cell, parotid gland, prefrontal cortex, renal medulla, Rostral migratory stream, secondary oocyte, skin of external ear, transitional epithelium of urinary bladder, ventromedial nucleus. Use these groups to spot repeated connection types before inspecting the individual relationships.

ACVR1B

Top relations

Gene ontology · 52
ACVR1B → activin binding, activin receptor activity, type I, activin receptor complex, activin receptor signaling pathway, activin-activated receptor activity, ATP binding, cell surface, central nervous system development, cytosol, development of primary female sexual characteristics, extrinsic apoptotic signaling pathway, G1/S transition of mitotic cell cycle, growth factor binding, hair follicle development, in utero embryonic development, inhibin binding, integral component of membrane, integral component of plasma membrane, kinase activity, membrane
Bgee · 20
ACVR1B → beta cell, Brodmann area 10, Brodmann area 23, epithelium of stomach, hair follicle, kidney tubule, lateral nuclear group of thalamus, middle temporal gyrus, nucleus accumbens, olfactory tubercle, pancreatic ductal cell, Paneth cell, parotid gland, prefrontal cortex, renal medulla, Rostral migratory stream, secondary oocyte, skin of external ear, transitional epithelium of urinary bladder, ventromedial nucleus
RNA expression pattern · 20
ACVR1B → beta cell, Brodmann area 10, Brodmann area 23, epithelium of stomach, hair follicle, kidney tubule, lateral nuclear group of thalamus, middle temporal gyrus, nucleus accumbens, olfactory tubercle, pancreatic ductal cell, Paneth cell, parotid gland, prefrontal cortex, renal medulla, Rostral migratory stream, secondary oocyte, skin of external ear, transitional epithelium of urinary bladder, ventromedial nucleus
Band · 2
ACVR1B → 12q13.13, 15 F1|15 56.48 cM
Chr. · 2
ACVR1B → Chromosome 12 (human), Chromosome 15 (mouse)
End · 2
ACVR1B → 101,111,565 bp, 51,997,078 bp
related to External links · 2
ACVR1B → Human ACVR1B, UCSC Genome Browser
related to Interactions · 2
ACVR1B → ACVR2A, ACVR2B
2.7.11.30 · 1
ACVR1B → ↗
Aliases · 1
ACVR1B → ACVR1B, ACTRIB, ACVRLK4, ALK4, SKR2, activin A receptor type 1B

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

activin bp gene human chr band type receptor protein chromosome 12 complex location 11 external ii receptors signals inhibin nodal

ACVR1B relationships Subject–Predicate–Object triples

TTTA extracted 122 structured relationships around ACVR1B. Examples in this analysis include ACVR1B → 2.7.11.30 → ↗ and ACVR1B → Aliases → ACVR1B, ACTRIB, ACVRLK4, ALK4, SKR2, activin A receptor type 1B. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ACVR1B2.7.11.301.00infobox
ACVR1BAliasesACVR1B, ACTRIB, ACVRLK4, ALK4, SKR2, activin A receptor type 1B1.00infobox
ACVR1BAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3H9R, 3MTF, 3OOM, 3Q4U, 4BGG, 4C02, 4DYM1.00infobox
ACVR1BBand12q13.131.00infobox
ACVR1BBand15 F1|15 56.48 cM1.00infobox
ACVR1BBgeesecondary oocyte1.00infobox
ACVR1BBgeemiddle temporal gyrus1.00infobox
ACVR1BBgeepancreatic ductal cell1.00infobox
ACVR1BBgeerenal medulla1.00infobox
ACVR1BBgeeBrodmann area 231.00infobox
ACVR1BBgeebeta cell1.00infobox
ACVR1BBgeelateral nuclear group of thalamus1.00infobox
ACVR1BBgeeparotid gland1.00infobox
ACVR1BBgeekidney tubule1.00infobox
ACVR1BBgeeBrodmann area 101.00infobox
ACVR1BBgeetransitional epithelium of urinary bladder1.00infobox
ACVR1BBgeeepithelium of stomach1.00infobox
ACVR1BBgeehair follicle1.00infobox
ACVR1BBgeeskin of external ear1.00infobox
ACVR1BBgeeolfactory tubercle1.00infobox
ACVR1BBgeeprefrontal cortex1.00infobox
ACVR1BBgeePaneth cell1.00infobox
ACVR1BBgeenucleus accumbens1.00infobox
ACVR1BBgeeventromedial nucleus1.00infobox
ACVR1BBgeeRostral migratory stream1.00infobox
ACVR1BBioGPSn/a1.00infobox
ACVR1BChr.Chromosome 12 (human)1.00infobox
ACVR1BChr.Chromosome 15 (mouse)1.00infobox
ACVR1BDatabasesNCBI: entry; OMA: entry1.00infobox
ACVR1BEnd51,997,078 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ACVR1B bring nearby vocabulary together. In this analysis, examples include Gene, Protein and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • ACVR1B
    • Gene
    • Protein
    • Location
    • Human
    • Receptor
    • Activity
    • Acvr2a
    • Acvr2b
    • External
    • Function
    • Inhibin
    • Nodal
  • acvr1b
    • Gene
    • Protein
    • Location
    • Human
    • Receptor
    • Activity
    • Acvr2a
    • Acvr2b
    • External
    • Function
    • Inhibin
    • Nodal
  • protein
    • Nodal
    • Acvr1b
    • Receptor
    • Gene
    • Activity
    • End
    • External
    • F1
    • Function
    • Inhibin
    • Mouse
    • Phosphorylation
  • gene
    • Location
    • Human
    • Receptor
    • Chromosome
    • Bp
    • Chr
    • Activity
    • End
    • External
    • F1
    • Function
    • Mouse
  • inhibin
    • Activity
    • End
    • External
    • F1
    • Function
    • Ligands
    • Mouse
    • Nodal
    • Phosphorylation
    • Search
    • Signaling
    • Signals
  • nodal
    • Protein
    • Activity
    • End
    • External
    • F1
    • Function
    • Mouse
    • Phosphorylation
    • Search
    • Signaling
    • Signals
    • Binding
  • function
    • Activity
    • Search
    • Chromosome
    • Location
    • Bp
    • Chr
    • Human
    • Receptor
    • End
    • F1
    • Gene
    • Inhibin
  • phosphorylation
    • Search
    • Signaling
    • Type
    • Protein
    • Serine
    • Receptors
    • Receptor

Connections between topic areas Semantic bridges

For ACVR1B, one of the stronger structural bridges in this analysis connects ACVR1B with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ACVR1BOverview · splits 8 ⟂ 13
ACVR1BFunction · splits 16 ⟂ 5

Map overview Semantic statistics

ACVR1B

Nodes21
Edges20
Triples122
Avg. degree1.9
Density0.095238
Components1

Source & methodology

TTTA analyzes the structure around ACVR1B to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Overview & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ACVR1B · EN edition · Analysis: TopicsToTalkAbout

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