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ACVR2A: Function, Interactions & Overview

Activin receptor type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor.

Language: English [EN]
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ACVR2A topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around ACVR2A.

Related topics
13
Source areas
3
Connected nodes
16
Extracted relationships
128
Concept neighborhoods
10
Bridge connections
16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 6 topics
Interactions · 4 topics
Overview · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.30
Aliases
ACVR2A, ACTRII, ACVR2, activin A receptor type 2A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3Q4T, 3SOC, 4ASX
Band
2q22.3-q23.1 · 2 C1.1|2 28.38 cM
Bgee
buccal mucosa cell · hair follicle · oocyte · skin of thigh · testicle
BioGPS
n/a

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ACVR2A connects Entity context

The extracted context around ACVR2A shows recurring relationship patterns in the source. For example, ACVR2A → activin binding, activin receptor complex, activin receptor signaling pathway, activin-activated receptor activity, anterior/posterior pattern specification, ATP binding, BMP receptor activity, BMP signaling pathway, cell surface, cellular response to BMP stimulus, coreceptor activity, cytoplasm, determination of left/right symmetry, ejaculation, embryonic skeletal system development, gastrulation with mouth forming second, growth factor binding, inhibin binding, inhibin-betaglycan-ActRII complex, integral component of membrane Another extracted example is ACVR2A → Achilles tendon, anterior amygdaloid area, buccal mucosa cell, epithelium of lens, ganglionic eminence, genital tubercle, hair follicle, lactiferous duct, medial ganglionic eminence, nucleus accumbens, olfactory tubercle, oocyte, skin of abdomen, skin of thigh, subiculum, tail of embryo, tendon, testicle, triceps brachii muscle, trigeminal ganglion. Use these groups to spot repeated connection types before inspecting the individual relationships.

ACVR2A

Top relations

Gene ontology · 58
ACVR2A → activin binding, activin receptor complex, activin receptor signaling pathway, activin-activated receptor activity, anterior/posterior pattern specification, ATP binding, BMP receptor activity, BMP signaling pathway, cell surface, cellular response to BMP stimulus, coreceptor activity, cytoplasm, determination of left/right symmetry, ejaculation, embryonic skeletal system development, gastrulation with mouth forming second, growth factor binding, inhibin binding, inhibin-betaglycan-ActRII complex, integral component of membrane
Bgee · 20
ACVR2A → Achilles tendon, anterior amygdaloid area, buccal mucosa cell, epithelium of lens, ganglionic eminence, genital tubercle, hair follicle, lactiferous duct, medial ganglionic eminence, nucleus accumbens, olfactory tubercle, oocyte, skin of abdomen, skin of thigh, subiculum, tail of embryo, tendon, testicle, triceps brachii muscle, trigeminal ganglion
RNA expression pattern · 20
ACVR2A → Achilles tendon, anterior amygdaloid area, buccal mucosa cell, epithelium of lens, ganglionic eminence, genital tubercle, hair follicle, lactiferous duct, medial ganglionic eminence, nucleus accumbens, olfactory tubercle, oocyte, skin of abdomen, skin of thigh, subiculum, tail of embryo, tendon, testicle, triceps brachii muscle, trigeminal ganglion
Band · 2
ACVR2A → 2 C1.1|2 28.38 cM, 2q22.3-q23.1
Chr. · 2
ACVR2A → Chromosome 2 (human), Chromosome 2 (mouse)
End · 2
ACVR2A → 147,930,826 bp, 48,793,281 bp
related to External links · 2
ACVR2A → Human ACVR2A, UCSC Genome Browser
related to Interactions · 2
ACVR2A → ACVR1B, INHBA
2.7.11.30 · 1
ACVR2A → ↗
Aliases · 1
ACVR2A → ACVR2A, ACTRII, ACVR2, activin A receptor type 2A

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

type receptor bp gene human activin chr band ii chromosome location receptors protein mouse binding serine complex signaling function external

ACVR2A relationships Subject–Predicate–Object triples

TTTA extracted 128 structured relationships around ACVR2A. Examples in this analysis include ACVR2A → 2.7.11.30 → ↗ and ACVR2A → Aliases → ACVR2A, ACTRII, ACVR2, activin A receptor type 2A. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ACVR2A2.7.11.301.00infobox
ACVR2AAliasesACVR2A, ACTRII, ACVR2, activin A receptor type 2A1.00infobox
ACVR2AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3Q4T, 3SOC, 4ASX1.00infobox
ACVR2ABand2q22.3-q23.11.00infobox
ACVR2ABand2 C1.1|2 28.38 cM1.00infobox
ACVR2ABgeebuccal mucosa cell1.00infobox
ACVR2ABgeehair follicle1.00infobox
ACVR2ABgeeoocyte1.00infobox
ACVR2ABgeeskin of thigh1.00infobox
ACVR2ABgeetesticle1.00infobox
ACVR2ABgeeskin of abdomen1.00infobox
ACVR2ABgeelactiferous duct1.00infobox
ACVR2ABgeeganglionic eminence1.00infobox
ACVR2ABgeetendon1.00infobox
ACVR2ABgeeAchilles tendon1.00infobox
ACVR2ABgeetrigeminal ganglion1.00infobox
ACVR2ABgeeolfactory tubercle1.00infobox
ACVR2ABgeesubiculum1.00infobox
ACVR2ABgeeanterior amygdaloid area1.00infobox
ACVR2ABgeemedial ganglionic eminence1.00infobox
ACVR2ABgeeepithelium of lens1.00infobox
ACVR2ABgeetriceps brachii muscle1.00infobox
ACVR2ABgeetail of embryo1.00infobox
ACVR2ABgeegenital tubercle1.00infobox
ACVR2ABgeenucleus accumbens1.00infobox
ACVR2ABioGPSn/a1.00infobox
ACVR2AChr.Chromosome 2 (human)1.00infobox
ACVR2AChr.Chromosome 2 (mouse)1.00infobox
ACVR2ADatabasesNCBI: entry; OMA: entry1.00infobox
ACVR2AEnd147,930,826 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ACVR2A bring nearby vocabulary together. In this analysis, examples include Gene, Receptor and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • ACVR2A
    • Gene
    • Receptor
    • Location
    • Human
    • Activity
    • Function
    • Protein
    • Search
    • Type
    • Chromosome
    • Bp
    • Chr
  • acvr2a
    • Gene
    • Receptor
    • Location
    • Human
    • Activity
    • Function
    • Protein
    • Search
    • Type
    • Chromosome
    • Bp
    • Chr
  • protein
    • Gene
    • Receptor
    • Activity
    • Acvr2a
    • C1
    • Domain
    • End
    • Expression
    • Function
    • Growth
    • Mouse
    • Phosphorylation
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Receptor
    • 3-q23
    • Activity
    • C1
    • End
    • Function
    • Mouse
  • activin type 2 receptor
    • Receptor
    • Ii
    • Acvr2a
    • Activity
    • Function
    • Gene
    • Protein
    • Receptors
    • Search
    • Type
    • Binding
    • Complex
  • receptor serine kinases
    • Threonine
    • Transmembrane
    • Type
    • Activity
    • Function
    • Search
    • Complex
    • Receptors
    • Serine
    • Chromosome
    • Location
    • Bp
  • function
    • Activity
    • Search
    • Chromosome
    • Location
    • Bp
    • Chr
    • Gene
    • Human
    • Receptor
    • 3-q23
    • C1
    • Domain
  • transmembrane domain
    • Threonine
    • Transmembrane
    • Serine
    • End
    • Expression
    • Function
    • Growth
    • Mouse
    • Phosphorylation
    • Protein
    • Search
    • Transforming

Connections between topic areas Semantic bridges

For ACVR2A, one of the stronger structural bridges in this analysis connects ACVR2A with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ACVR2AFunction · splits 10 ⟂ 7
ACVR2AInteractions · splits 12 ⟂ 5
ACVR2AOverview · splits 13 ⟂ 4

Map overview Semantic statistics

ACVR2A

Nodes17
Edges16
Triples128
Avg. degree1.88
Density0.117647
Components1

Source & methodology

TTTA analyzes the structure around ACVR2A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ACVR2A · EN edition · Analysis: TopicsToTalkAbout

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