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Malonyl-CoA decarboxylase: Applications, Processing and post-translational modifications & Functions

Malonyl-CoA decarboxylase (EC 4.1.1.9), (which can also be called MCD and malonyl-CoA carboxyl-lyase) is found in bacteria and humans and has important roles in regulating fatty acid metabolism and food intake, and it is an attractive target for drug discovery. It is an enzyme associated with Malonyl-CoA decarboxylase deficiency. In humans, it is encoded…

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Malonyl-CoA decarboxylase topic overview

The analysis highlights Applications, Processing and post-translational modifications and Functions as prominent areas in the source structure around Malonyl-CoA decarboxylase.

Related topics
51
Source areas
7
Connected nodes
58
Extracted relationships
33
Related term clusters
21
Bridge connections
58

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Processing and post-translational modifications · 13 topics
Functions · 12 topics
Structure · 9 topics
Overview · 7 topics
Localization · 5 topics
Enzyme regulation · 3 topics
Medical applications · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

BRENDA
enzyme data
CAS no.
9024-99-1
EC no.
4.1.1.9
ExPASy
NiceZyme view
Gene Ontology
AmiGO / QuickGO
KEGG
enzyme entry

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Explore different angles and find fresh ideas to shape your next piece of content.

Malonyl-CoA decarboxylase
3Malonyl-CoA · Metabolite · Malonyl-CoA decarboxylase deficiency
8Enzyme · Acetyl-CoA · Peroxisomes
7Post-translational modification · Acetylation · Lysine
5Cytosolic · Mitochondrial · Peroxisomal

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Processing and post-translational modifications

Functions

Localization

Enzyme regulation

Medical applications

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Malonyl-CoA decarboxylase connects Entity context

The extracted context around Malonyl-CoA decarboxylase shows recurring relationship patterns in the source. For example, Malonyl-CoA decarboxylase → Another, CoA, Malonyl-CoA, MCD, PTM, Similarly, SIRT4 Another extracted example is Malonyl-CoA decarboxylase → CoA, Malonyl-CoA, MCD. Use these groups to spot repeated connection types before inspecting the individual relationships.

Malonyl-CoA decarboxylase

Top relations

related to Processing and post-translational modifications · 7
Malonyl-CoA decarboxylase → Another, CoA, Malonyl-CoA, MCD, PTM, Similarly, SIRT4
related to Functions · 3
Malonyl-CoA decarboxylase → CoA, Malonyl-CoA, MCD
related to Gene: MLYCD · 3
Malonyl-CoA decarboxylase → CoA, MCD, MLYCD
related to Localization · 2
Malonyl-CoA decarboxylase → Malonyl-CoA, MCD
BRENDA · 1
Malonyl-CoA decarboxylase → enzyme data
CAS no. · 1
Malonyl-CoA decarboxylase → 9024-99-1
EC no. · 1
Malonyl-CoA decarboxylase → 4.1.1.9
ExPASy · 1
Malonyl-CoA decarboxylase → NiceZyme view
Gene Ontology · 1
Malonyl-CoA decarboxylase → AmiGO / QuickGO
KEGG · 1
Malonyl-CoA decarboxylase → enzyme entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

malonyl-coa mcd fatty enzyme acid decarboxylase acetyl-coa also peroxisomes gene acids mitochondrial mlycd mitochondria one amino oxidation malonic peroxisomal sites

Malonyl-CoA decarboxylase relationships Subject–Predicate–Object triples

TTTA extracted 33 structured relationships around Malonyl-CoA decarboxylase. Examples in this analysis include Malonyl-CoA decarboxylase → BRENDA → enzyme data and Malonyl-CoA decarboxylase → CAS no. → 9024-99-1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Malonyl-CoA decarboxylaseBRENDAenzyme data1.00infobox
Malonyl-CoA decarboxylaseCAS no.9024-99-11.00infobox
Malonyl-CoA decarboxylaseEC no.4.1.1.91.00infobox
Malonyl-CoA decarboxylaseExPASyNiceZyme view1.00infobox
Malonyl-CoA decarboxylaseGene OntologyAmiGO / QuickGO1.00infobox
Malonyl-CoA decarboxylaseKEGGenzyme entry1.00infobox
Malonyl-CoA decarboxylaseMetaCycmetabolic pathway1.00infobox
Malonyl-CoA decarboxylaseNCBIproteins1.00infobox
Malonyl-CoA decarboxylasePDB structuresRCSB PDB PDBe PDBsum1.00infobox
Malonyl-CoA decarboxylasePMCarticles1.00infobox
Malonyl-CoA decarboxylasePubMedarticles1.00infobox
Malonyl-CoA decarboxylaseRheareactions1.00infobox
Malonyl-CoA decarboxylaseSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Malonyl-CoA decarboxylase bring nearby vocabulary together. In this analysis, examples include Malonyl-coa, Fatty and Mcd. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Malonyl-CoA decarboxylase
    • Malonyl-coa
    • Fatty
    • Mcd
    • Acids
    • Acetyl-coa
    • Mitochondria
    • Enzyme
    • Acid
    • Mitochondrial
    • Oxidation
    • Important
    • Peroxisomal
  • malonyl-coa decarboxylase
    • Malonyl-coa
    • Fatty
    • Mcd
    • Enzyme
    • Acids
    • Acetyl-coa
    • Mitochondria
    • Acid
    • Mitochondrial
    • Oxidation
    • Amino
    • Mlycd
  • malonyl-coa decarboxylase deficiency
    • Malonyl-coa
    • Fatty
    • Mcd
    • Enzyme
    • Mlycd
    • Acids
    • Peroxisomes
    • Acetyl-coa
    • Mitochondria
    • Acid
    • Mitochondrial
    • Oxidation
  • malonyl-coa
    • Fatty
    • Mcd
    • Acids
    • Acetyl-coa
    • Mitochondria
    • Enzyme
    • Acid
    • Mitochondrial
    • Oxidation
    • Important
    • Peroxisomal
    • Regulation
  • fatty acid biosynthesis
    • Oxidation
    • Acids
    • Acid
    • Fatty
    • Malonyl-coa
    • Amino
    • Mitochondrial
    • Mitochondria
    • Chain
    • Involved
    • Mcd
    • Acetyl-coa
  • fatty acid oxidation
    • Oxidation
    • Acids
    • Acid
    • Fatty
    • Malonyl-coa
    • Amino
    • Mitochondrial
    • Mitochondria
    • Chain
    • Involved
    • Mcd
    • Acetyl-coa
  • enzyme
    • Amino
    • Peroxisomes
    • Acids
    • Form
    • Malonyl-coa
    • Mitochondrial
    • Oxidation
    • Gene
    • Mitochondria
    • Mcd
    • Fatty
    • Found
  • peroxisomes
    • Malonic
    • Enzyme
    • Chain
    • Deficiency
    • Long
    • Gene
    • Mitochondria
    • Mcd
    • Acids
    • Fatty
    • Malonyl-coa
    • Found

Connections between topic areas Semantic bridges

For Malonyl-CoA decarboxylase, one of the stronger structural bridges in this analysis connects Malonyl-CoA decarboxylase with Processing and post-translational modifications. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Malonyl-CoA decarboxylase — Processing and post-translational modifications · splits 45 ⟂ 14
Malonyl-CoA decarboxylase — Functions · splits 46 ⟂ 13
Malonyl-CoA decarboxylase — Structure · splits 49 ⟂ 10
Malonyl-CoA decarboxylase — Overview · splits 51 ⟂ 8
Malonyl-CoA decarboxylase — Localization · splits 53 ⟂ 6
Malonyl-CoA decarboxylase — Enzyme regulation · splits 55 ⟂ 4
Malonyl-CoA decarboxylase — Medical applications · splits 56 ⟂ 3

Map overview Semantic statistics

Malonyl-CoA decarboxylase

Nodes59
Edges58
Triples33
Avg. degree1.97
Density0.033898
Components1

Source & methodology

TTTA analyzes the structure around Malonyl-CoA decarboxylase to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Processing and post-translational modifications & Functions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Malonyl-CoA decarboxylase · EN edition · Analysis: TopicsToTalkAbout

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