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Angiotensin-converting enzyme 2

Angiotensin-converting enzyme 2 (ACE2) is an enzyme that can be found either attached to the membrane of cells (mACE2) in the intestines, kidney, testis, gallbladder, and heart or in a soluble form (sACE2). Both membrane bound and soluble ACE2 are integral parts of the renin–angiotensin–aldosterone system (RAAS) that exists to keep the body's blood…

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3.4.17.23
↗
Aliases
ACE2, ACEH, angiotensin I converting enzyme 2, ACE 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3SCL, 1R42, 1R4L, 2AJF, 3D0G, 3D0H, 3D0I, 3KBH, 3SCI, 3SCJ, 3SCK
Band
Xp22.2 · X F5|X 76.12 cM
Bgee
mucosa of ileum · gallbladder · jejunal mucosa · duodenum · right testis
BioGPS
More reference expression data

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Angiotensin-converting enzyme 2

Nodes95
Edges94
Triples136
Avg. degree1.98
Density0.021053
Components1

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Angiotensin-converting enzyme 2

Top relations

Gene ontology · 40
Angiotensin-converting enzyme 2 → angiotensin maturation, angiotensin-mediated drinking behavior, blood vessel diameter maintenance, brush border membrane, carboxypeptidase activity, cell surface, cytoplasm, endopeptidase activity, exopeptidase activity, extracellular exosome, extracellular region, extracellular space, hydrolase activity, integral component of membrane, membrane, membrane raft, metal ion binding, metallocarboxypeptidase activity, metallopeptidase activity, peptidase activity
Bgee · 19
Angiotensin-converting enzyme 2 → apex of heart, duodenum, epithelium of small intestine, esophagus, gallbladder, human kidney, Ileal epithelium, ileum, intestinal villus, jejunal mucosa, jejunum, left testis, left ventricle, migratory enteric neural crest cell, mucosa of ileum, mucosa of transverse colon, Paneth cell, right testis, stroma of kidney
RNA expression pattern · 19
Angiotensin-converting enzyme 2 → apex of heart, duodenum, epithelium of small intestine, esophagus, gallbladder, human kidney, Ileal epithelium, ileum, intestinal villus, jejunal mucosa, jejunum, left testis, left ventricle, migratory enteric neural crest cell, mucosa of ileum, mucosa of transverse colon, Paneth cell, right testis, stroma of kidney
related to Structure · 15
Angiotensin-converting enzyme 2 → ACE2, ADAM17, Aldosterone System, Angiotensin, C-terminal, Excess, II, It, M2, MasR, Membrane, N-terminal, RAAS, Renin, The
related to External links · 12
Angiotensin-converting enzyme 2 → ACE2, Angiotensin-converting, AT1, Human ACE2, Membranome, OPM, PDB, PDBe-KB, Q9BYF1, SARS-CoV-2, UCSC Genome Browser, UniProt
Band · 2
Angiotensin-converting enzyme 2 → X F5|X 76.12 cM, Xp22.2
Chr. · 2
Angiotensin-converting enzyme 2 → X chromosome (human), X chromosome (mouse)
End · 2
Angiotensin-converting enzyme 2 → 15,602,148 bp, 162,971,416 bp
3.4.17.23 · 1
Angiotensin-converting enzyme 2 → ↗
Aliases · 1
Angiotensin-converting enzyme 2 → ACE2, ACEH, angiotensin I converting enzyme 2, ACE 2

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Important terminology

ace2 mace2 angiotensin enzyme blood sars-cov-2 also pressure protein entry human membrane cells sace2 soluble domain ii covid-19 bp ace

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Angiotensin-converting enzyme 23.4.17.23↗1.00infobox
Angiotensin-converting enzyme 2AliasesACE2, ACEH, angiotensin I converting enzyme 2, ACE 21.00infobox
Angiotensin-converting enzyme 2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3SCL, 1R42, 1R4L, 2AJF, 3D0G, 3D0H, 3D0I, 3KBH, 3SCI, 3SCJ, 3SCK1.00infobox
Angiotensin-converting enzyme 2BandXp22.21.00infobox
Angiotensin-converting enzyme 2BandX F5|X 76.12 cM1.00infobox
Angiotensin-converting enzyme 2Bgeemucosa of ileum1.00infobox
Angiotensin-converting enzyme 2Bgeegallbladder1.00infobox
Angiotensin-converting enzyme 2Bgeejejunal mucosa1.00infobox
Angiotensin-converting enzyme 2Bgeeduodenum1.00infobox
Angiotensin-converting enzyme 2Bgeeright testis1.00infobox
Angiotensin-converting enzyme 2Bgeeleft testis1.00infobox
Angiotensin-converting enzyme 2Bgeeleft ventricle1.00infobox
Angiotensin-converting enzyme 2Bgeehuman kidney1.00infobox
Angiotensin-converting enzyme 2Bgeemucosa of transverse colon1.00infobox
Angiotensin-converting enzyme 2Bgeeapex of heart1.00infobox
Angiotensin-converting enzyme 2Bgeeileum1.00infobox
Angiotensin-converting enzyme 2Bgeejejunum1.00infobox
Angiotensin-converting enzyme 2Bgeeepithelium of small intestine1.00infobox
Angiotensin-converting enzyme 2Bgeeintestinal villus1.00infobox
Angiotensin-converting enzyme 2Bgeestroma of kidney1.00infobox
Angiotensin-converting enzyme 2BgeeIleal epithelium1.00infobox
Angiotensin-converting enzyme 2Bgeemigratory enteric neural crest cell1.00infobox
Angiotensin-converting enzyme 2BgeePaneth cell1.00infobox
Angiotensin-converting enzyme 2Bgeeesophagus1.00infobox
Angiotensin-converting enzyme 2BioGPSMore reference expression data1.00infobox
Angiotensin-converting enzyme 2Chr.X chromosome (human)1.00infobox
Angiotensin-converting enzyme 2Chr.X chromosome (mouse)1.00infobox
Angiotensin-converting enzyme 2DatabasesNCBI: entry; OMA: entry1.00infobox
Angiotensin-converting enzyme 2End15,602,148 bp1.00infobox
Angiotensin-converting enzyme 2End162,971,416 bp1.00infobox

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