Emerin

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Emerin topic overview

The analysis highlights Interactions, Function and Clinical significance as prominent areas in the source structure around Emerin.

Related topics: 44
Source areas: 5
Connected nodes: 49
Extracted relationships: 128
Concept neighborhoods: 19
Bridge connections: 49

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 14 topics

Interactions · 12 topics

Function · 7 topics

Clinical significance · 6 topics

Structure · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: EMD, EDMD, LEMD5, STA, emerin
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1JEI, 2ODC, 2ODG
Band: Xq28 · X A7.3|X 37.92 cM
Bgee: left ovary · left uterine tube · popliteal artery · tibial arteries · right ovary
BioGPS: More reference expression data
Chr.: X chromosome (human) · X chromosome (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

LEMD3
Integral Transmembrane protein
Protein
Inner Inner nuclear membrane proteins
Nuclear Cell nucleus
Cardiac muscle
Skeletal muscle
Adherens junctions Adherens junction
Intercalated discs Intercalated disc
Beta-catenin CTNNB1
X-linked recessive X-linked recessive inheritance
Emery–Dreifuss muscular dystrophy
Dilated cardiomyopathy
Alan Emery

Structure

Function

Clinical significance

Sinus bradycardia
PR prolongation First-degree atrioventricular block
Heart block
Fibroblasts Fibroblast
Leukocytes Leukocyte
HIV-1

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Emerin connects Entity context

The extracted context around Emerin shows recurring relationship patterns in the source. For example, Emerin → actin binding, beta-tubulin binding, cadherin binding, cellular response to growth factor stimulus, cortical endoplasmic reticulum, cytoplasm, endoplasmic reticulum, integral component of membrane, membrane, microtubule, mitotic nuclear membrane disassembly, mitotic nuclear membrane reassembly, muscle contraction, muscle organ development, negative regulation of canonical Wnt signaling pathway, negative regulation of fibroblast proliferation, nuclear envelope, nuclear inner membrane, nuclear membrane, nuclear outer membrane Another extracted example is Emerin → anterior pituitary, aortic valve, ascending aorta, body of uterus, Descending thoracic aorta, gastric mucosa, genital tubercle, granulocyte, left ovary, left uterine tube, lip, medial ganglionic eminence, muscle of thigh, popliteal artery, right coronary artery, right ovary, tail of embryo, tibial arteries, ventricular zone, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 28

Emerin → actin binding, beta-tubulin binding, cadherin binding, cellular response to growth factor stimulus, cortical endoplasmic reticulum, cytoplasm, endoplasmic reticulum, integral component of membrane, membrane, microtubule, mitotic nuclear membrane disassembly, mitotic nuclear membrane reassembly, muscle contraction, muscle organ development, negative regulation of canonical Wnt signaling pathway, negative regulation of fibroblast proliferation, nuclear envelope, nuclear inner membrane, nuclear membrane, nuclear outer membrane

Bgee · 20

Emerin → anterior pituitary, aortic valve, ascending aorta, body of uterus, Descending thoracic aorta, gastric mucosa, genital tubercle, granulocyte, left ovary, left uterine tube, lip, medial ganglionic eminence, muscle of thigh, popliteal artery, right coronary artery, right ovary, tail of embryo, tibial arteries, ventricular zone, yolk sac

RNA expression pattern · 20

related to Clinical significance · 12

Emerin → Achilles, Approximately, Dreifuss, Emery, HIV-1, In, Moreover, Mutations, PR, Thus, X-linked, Xq28

related to Interactions · 11

Emerin → ACTA1, ACTG2, BANF1, BCLAF1, CTNNB1, GMCL1, LMNA, PSME1, SYNE1, SYNE2, TMEM43

related to Function · 8

Emerin → Dreifuss, EMD, Emery, In, It, STA, This, X-linked

related to Structure · 3

Emerin → In, MW, N-terminal

Band · 2

Emerin → X A7.3|X 37.92 cM, Xq28

Chr. · 2

Emerin → X chromosome (human), X chromosome (mouse)

End · 2

Emerin → 154,381,574 bp, 73,305,154 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein cardiac muscle gene bp human emery membrane emd chr band dreifuss muscular dystrophy chromosome nuclear skeletal function also inner

Emerin relationships Subject–Predicate–Object triples

TTTA extracted 128 structured relationships around Emerin. Examples in this analysis include Emerin → Aliases → EMD, EDMD, LEMD5, STA, emerin and Emerin → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1JEI, 2ODC, 2ODG. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Emerin	Aliases	EMD, EDMD, LEMD5, STA, emerin	1.00	infobox
Emerin	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1JEI, 2ODC, 2ODG	1.00	infobox
Emerin	Band	Xq28	1.00	infobox
Emerin	Band	X A7.3\|X 37.92 cM	1.00	infobox
Emerin	Bgee	left ovary	1.00	infobox
Emerin	Bgee	left uterine tube	1.00	infobox
Emerin	Bgee	popliteal artery	1.00	infobox
Emerin	Bgee	tibial arteries	1.00	infobox
Emerin	Bgee	right ovary	1.00	infobox
Emerin	Bgee	anterior pituitary	1.00	infobox
Emerin	Bgee	gastric mucosa	1.00	infobox
Emerin	Bgee	body of uterus	1.00	infobox
Emerin	Bgee	right coronary artery	1.00	infobox
Emerin	Bgee	Descending thoracic aorta	1.00	infobox
Emerin	Bgee	genital tubercle	1.00	infobox
Emerin	Bgee	tail of embryo	1.00	infobox
Emerin	Bgee	ventricular zone	1.00	infobox
Emerin	Bgee	yolk sac	1.00	infobox
Emerin	Bgee	lip	1.00	infobox
Emerin	Bgee	granulocyte	1.00	infobox
Emerin	Bgee	medial ganglionic eminence	1.00	infobox
Emerin	Bgee	muscle of thigh	1.00	infobox
Emerin	Bgee	ascending aorta	1.00	infobox
Emerin	Bgee	aortic valve	1.00	infobox
Emerin	BioGPS	More reference expression data	1.00	infobox
Emerin	Chr.	X chromosome (human)	1.00	infobox
Emerin	Chr.	X chromosome (mouse)	1.00	infobox
Emerin	Databases	NCBI: entry; OMA: entry	1.00	infobox
Emerin	End	154,381,574 bp	1.00	infobox
Emerin	End	73,305,154 bp	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Emerin bring nearby vocabulary together. In this analysis, examples include Muscle, Cardiac and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Emerin
- Muscle
- Cardiac
- Protein
- Membrane
- Nuclear
- Gene
- Adherens
- Discs
- Expression
- Function
- Inner
- Intercalated
emerin
- Muscle
- Cardiac
- Protein
- Membrane
- Nuclear
- Gene
- Adherens
- Discs
- Expression
- Function
- Inner
- Intercalated
protein
- Membrane
- Nuclear
- Integral
- Inner
- Human
- Muscle
- Cellular
- Expressed
- Signaling
- Expression
- Function
- Location
cardiac muscle
- Muscle
- Adherens
- Discs
- Intercalated
- Junctions
- Emerin
- Skeletal
- Beta-catenin
- Cellular
- Mutations
- Signaling
- Within
skeletal muscle
- Expressed
- Expression
- Inner
- Nuclear
- Adherens
- Discs
- Intercalated
- Junctions
- Muscle
- Skeletal
- Membrane
- Beta-catenin
smooth muscle
- Adherens
- Discs
- Intercalated
- Junctions
- Skeletal
- Beta-catenin
- Cellular
- Signaling
- Expression
- Function
- Within
- Nuclear
gene
- Location
- Mouse
- Sta
- Chromosome
- Bp
- Chr
- Human
- Expression
- Function
- Band
- External
- Protein
function
- Cellular
- Signaling
- Location
- Chromosome
- Bp
- Chr
- External
- Human
- Gene
- Integral
- Muscle
- Expression

Connections between topic areas Semantic bridges

For Emerin, one of the stronger structural bridges in this analysis connects Emerin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Emerin — Overview · splits 35 ⟂ 15

Emerin — Interactions · splits 37 ⟂ 13

Emerin — Function · splits 42 ⟂ 8

Emerin — Clinical significance · splits 43 ⟂ 7

Emerin — Structure · splits 44 ⟂ 6

Map overview Semantic statistics

Emerin

Nodes50

Edges49

Triples128

Avg. degree1.96

Density0.04

Components1

Source & methodology

TTTA analyzes the structure around Emerin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Emerin · EN edition · Analysis: TopicsToTalkAbout