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Wings apart-like protein homolog (WAPL) is a protein that in humans is encoded by the WAPL gene (previously WAPAL). WAPL is a key regulator of the Cohesin complex which mediates sister chromatid cohesion, homologous recombination and DNA looping. Cohesin is formed of SMC3, SMC1, RAD21 and either SA1 or SA2. Cohesin has a ring-like arrangement and it is…
The analysis highlights Art, Interphase and Overview as prominent areas in the source structure around WAPAL.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around WAPAL shows recurring relationship patterns in the source. For example, WAPAL → cell cycle, cell division, chromatin, chromosome, chromosome, centromeric region, cohesin complex, cytoplasm, cytosol, meiotic chromosome segregation, mitotic cell cycle, mitotic sister chromatid cohesion, negative regulation of chromatin binding, negative regulation of DNA replication, negative regulation of sister chromatid cohesion, nucleoplasm, nucleus, positive regulation of fibroblast proliferation, protein binding, protein localization to chromatin, regulation of chromosome condensation Another extracted example is WAPAL → Achilles tendon, amniotic fluid, caput epididymis, genital tubercle, gonad, hair follicle, otolith organ, Paneth cell, primary oocyte, secondary oocyte, skin of hip, skin of thigh, sperm, tail of embryo, testicle, ureter, utricle, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
cohesin wapl dna chromosome sister bp complex chr human band gene 10 smc3 rad21 chromatid cohesion binding location opening interface
TTTA extracted 86 structured relationships around WAPAL. Examples in this analysis include WAPAL → Aliases → WAPL, FOE, KIAA0261, WAPAL, WAPL cohesin release factor and WAPAL → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4K6J, 5HDT. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| WAPAL | Aliases | WAPL, FOE, KIAA0261, WAPAL, WAPL cohesin release factor | 1.00 | infobox |
| WAPAL | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4K6J, 5HDT | 1.00 | infobox |
| WAPAL | Band | 10q23.2 | 1.00 | infobox |
| WAPAL | Band | 14|14 B | 1.00 | infobox |
| WAPAL | Bgee | secondary oocyte | 1.00 | infobox |
| WAPAL | Bgee | sperm | 1.00 | infobox |
| WAPAL | Bgee | ventricular zone | 1.00 | infobox |
| WAPAL | Bgee | amniotic fluid | 1.00 | infobox |
| WAPAL | Bgee | gonad | 1.00 | infobox |
| WAPAL | Bgee | testicle | 1.00 | infobox |
| WAPAL | Bgee | skin of thigh | 1.00 | infobox |
| WAPAL | Bgee | Achilles tendon | 1.00 | infobox |
| WAPAL | Bgee | skin of hip | 1.00 | infobox |
| WAPAL | Bgee | caput epididymis | 1.00 | infobox |
| WAPAL | Bgee | zygote | 1.00 | infobox |
| WAPAL | Bgee | tail of embryo | 1.00 | infobox |
| WAPAL | Bgee | otolith organ | 1.00 | infobox |
| WAPAL | Bgee | utricle | 1.00 | infobox |
| WAPAL | Bgee | primary oocyte | 1.00 | infobox |
| WAPAL | Bgee | hair follicle | 1.00 | infobox |
| WAPAL | Bgee | Paneth cell | 1.00 | infobox |
| WAPAL | Bgee | ureter | 1.00 | infobox |
| WAPAL | Bgee | genital tubercle | 1.00 | infobox |
| WAPAL | BioGPS | More reference expression data | 1.00 | infobox |
| WAPAL | Chr. | Chromosome 10 (human) | 1.00 | infobox |
| WAPAL | Chr. | Chromosome 14 (mouse) | 1.00 | infobox |
| WAPAL | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| WAPAL | End | 86,521,792 bp | 1.00 | infobox |
| WAPAL | End | 34,469,940 bp | 1.00 | infobox |
| WAPAL | Ensembl | ENSG00000062650 | 1.00 | infobox |
The concept neighborhoods around WAPAL bring nearby vocabulary together. In this analysis, examples include Pathway, Prophase and Search. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For WAPAL, one of the stronger structural bridges in this analysis connects WAPAL with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around WAPAL to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Interphase & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — WAPAL · EN edition · Analysis: TopicsToTalkAbout