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Explore the main themes, entities and connections around TRIM32. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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Function
11 related topics
Interactions
6 related topics
Clinical significance
5 related topics
Structure
4 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- 2.3.2.27
- ↗
- Aliases
- TRIM32, BBS11, HT2A, LGMD2H, TATIP, tripartite motif containing 32, LGMDR8
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CT2, 5FEY
- Band
- 9q33.1 · 4 C1|4 34.43 cM
- Bgee
- stromal cell of endometrium · tibialis anterior muscle · gastrocnemius muscle · secondary oocyte · testicle
- BioGPS
- More reference expression data
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
Structure
- Tripartite motif Tripartite motif family
- Zinc-binding Zinc finger
- RING RING domain
- Coiled-coil Coiled coil
Subcellular distribution
- Cytoplasmic bodies Cytoplasmic body?action=edit&redlink=1
- Nucleus Cell nucleus
- HIV-1 Subtypes of HIV
- Tat Tat (HIV)
Interactions
Function
- N-terminal N-terminus
- Ubiquitin ligase
- Proteosome
- C-terminal C-terminus
- NHL repeat
- MiRNAs MicroRNA
- Neocortex
- Argonaute-1 EIF2C1
- Let-7a Let-7 microRNA precursor
- Skeletal muscle Skeletal striated muscle
- Ubiquitinate Ubiquitin
Clinical significance
- Bardet–Biedl syndrome
- Limb-girdle muscular dystrophy
- NF-κB
- Keratinocytes Keratinocyte
- Tumor suppressor Tumor suppressor gene
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.TRIM32
Nodes39
Edges38
Triples164
Avg. degree1.95
Density0.051282
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
TRIM32
Top relations
Gene ontology · 51
TRIM32 → actin ubiquitination, axon development, cytoplasm, cytosol, fat cell differentiation, identical protein binding, innate immune response, intracellular anatomical structure, metal ion binding, muscle cell cellular homeostasis, myosin binding, negative regulation of fibroblast proliferation, negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage, negative regulation of viral transcription, nucleus, positive regulation of cell cycle, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell motility, positive regulation of chemokine (C-C motif) ligand 20 production
Bgee · 20
TRIM32 → bronchial epithelial cell, deltoid muscle, dorsal tegmental nucleus, dorsomedial hypothalamic nucleus, gastrocnemius muscle, gonad, habenula, lobe of cerebellum, medial geniculate nucleus, muscle of thigh, piriform cortex, secondary oocyte, Skeletal muscle tissue of biceps brachii, stromal cell of endometrium, subiculum, superior colliculus, testicle, tibialis anterior muscle, ventral tegmental area, visual cortex
RNA expression pattern · 20
TRIM32 → bronchial epithelial cell, deltoid muscle, dorsal tegmental nucleus, dorsomedial hypothalamic nucleus, gastrocnemius muscle, gonad, habenula, lobe of cerebellum, medial geniculate nucleus, muscle of thigh, piriform cortex, secondary oocyte, Skeletal muscle tissue of biceps brachii, stromal cell of endometrium, subiculum, superior colliculus, testicle, tibialis anterior muscle, ventral tegmental area, visual cortex
related to Mutation-associated diseases · 14
TRIM32 → B-box, Bardet, BBS, Biedl, C-terminal NHL, D487N, D588del, LGMD2H, Limb-girdle, NHL, P130S, R394H, Specifically, T520TfsX13
related to Cancer · 10
TRIM32 → Abi2, Abl-interactor, Activated STAT, It, NF-κB, Piasy, Protein Inhibitor, Thus, TNFα, When TRIM32
related to Development · 9
TRIM32 → Ago-1, Argonaute-1, In, Let-7a, Myc, Proposed, Research, The, This
related to Mechanism · 9
TRIM32 → ABI2, Abl-interactor2, C-terminal NHL, Currently, E3, First, Myc, N-terminal RING, The
related to Skeletal muscle · 5
TRIM32 → Additionally, LGMD2H, LHMD2H-mutated TRIM32, No, The
Band · 2
TRIM32 → 4 C1|4 34.43 cM, 9q33.1
Chr. · 2
TRIM32 → Chromosome 4 (mouse), Chromosome 9 (human)
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
protein bp piasy gene chr human band shown actin motif chromosome cancer mouse cell binding tripartite dysbindin nf-κb skeletal cells
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TRIM32 | 2.3.2.27 | ↗ | 1.00 | infobox |
| TRIM32 | Aliases | TRIM32, BBS11, HT2A, LGMD2H, TATIP, tripartite motif containing 32, LGMDR8 | 1.00 | infobox |
| TRIM32 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CT2, 5FEY | 1.00 | infobox |
| TRIM32 | Band | 9q33.1 | 1.00 | infobox |
| TRIM32 | Band | 4 C1|4 34.43 cM | 1.00 | infobox |
| TRIM32 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| TRIM32 | Bgee | tibialis anterior muscle | 1.00 | infobox |
| TRIM32 | Bgee | gastrocnemius muscle | 1.00 | infobox |
| TRIM32 | Bgee | secondary oocyte | 1.00 | infobox |
| TRIM32 | Bgee | testicle | 1.00 | infobox |
| TRIM32 | Bgee | muscle of thigh | 1.00 | infobox |
| TRIM32 | Bgee | deltoid muscle | 1.00 | infobox |
| TRIM32 | Bgee | gonad | 1.00 | infobox |
| TRIM32 | Bgee | Skeletal muscle tissue of biceps brachii | 1.00 | infobox |
| TRIM32 | Bgee | bronchial epithelial cell | 1.00 | infobox |
| TRIM32 | Bgee | dorsomedial hypothalamic nucleus | 1.00 | infobox |
| TRIM32 | Bgee | piriform cortex | 1.00 | infobox |
| TRIM32 | Bgee | habenula | 1.00 | infobox |
| TRIM32 | Bgee | ventral tegmental area | 1.00 | infobox |
| TRIM32 | Bgee | superior colliculus | 1.00 | infobox |
| TRIM32 | Bgee | subiculum | 1.00 | infobox |
| TRIM32 | Bgee | visual cortex | 1.00 | infobox |
| TRIM32 | Bgee | dorsal tegmental nucleus | 1.00 | infobox |
| TRIM32 | Bgee | medial geniculate nucleus | 1.00 | infobox |
| TRIM32 | Bgee | lobe of cerebellum | 1.00 | infobox |
| TRIM32 | BioGPS | More reference expression data | 1.00 | infobox |
| TRIM32 | Chr. | Chromosome 9 (human) | 1.00 | infobox |
| TRIM32 | Chr. | Chromosome 4 (mouse) | 1.00 | infobox |
| TRIM32 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| TRIM32 | End | 116,701,300 bp | 1.00 | infobox |
No triples extracted yet.
Related concept clusters Concept neighborhoods
Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.These clusters group vocabulary that occurs around closely connected concepts in the source material.
Connections between topic areas Semantic bridges
Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.
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