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TRIM32: Art, Function & Interactions

Tripartite motif-containing protein 32 is a protein that in humans is encoded by the TRIM32 gene. Since its discovery in 1995, TRIM32 has been shown to be implicated in a number of diverse biological pathways.

Language: English [EN]
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TRIM32 topic overview

The analysis highlights Art, Function and Interactions as prominent areas in the source structure around TRIM32.

Related topics
32
Source areas
6
Connected nodes
38
Extracted relationships
164
Concept neighborhoods
15
Bridge connections
38

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 11 topics
Interactions · 6 topics
Clinical significance · 5 topics
Structure · 4 topics
Subcellular distribution · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.3.2.27
Aliases
TRIM32, BBS11, HT2A, LGMD2H, TATIP, tripartite motif containing 32, LGMDR8
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CT2, 5FEY
Band
9q33.1 · 4 C1|4 34.43 cM
Bgee
stromal cell of endometrium · tibialis anterior muscle · gastrocnemius muscle · secondary oocyte · testicle
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Subcellular distribution

Interactions

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How TRIM32 connects Entity context

The extracted context around TRIM32 shows recurring relationship patterns in the source. For example, TRIM32 → actin ubiquitination, axon development, cytoplasm, cytosol, fat cell differentiation, identical protein binding, innate immune response, intracellular anatomical structure, metal ion binding, muscle cell cellular homeostasis, myosin binding, negative regulation of fibroblast proliferation, negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage, negative regulation of viral transcription, nucleus, positive regulation of cell cycle, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell motility, positive regulation of chemokine (C-C motif) ligand 20 production Another extracted example is TRIM32 → bronchial epithelial cell, deltoid muscle, dorsal tegmental nucleus, dorsomedial hypothalamic nucleus, gastrocnemius muscle, gonad, habenula, lobe of cerebellum, medial geniculate nucleus, muscle of thigh, piriform cortex, secondary oocyte, Skeletal muscle tissue of biceps brachii, stromal cell of endometrium, subiculum, superior colliculus, testicle, tibialis anterior muscle, ventral tegmental area, visual cortex. Use these groups to spot repeated connection types before inspecting the individual relationships.

TRIM32

Top relations

Gene ontology · 51
TRIM32 → actin ubiquitination, axon development, cytoplasm, cytosol, fat cell differentiation, identical protein binding, innate immune response, intracellular anatomical structure, metal ion binding, muscle cell cellular homeostasis, myosin binding, negative regulation of fibroblast proliferation, negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage, negative regulation of viral transcription, nucleus, positive regulation of cell cycle, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell motility, positive regulation of chemokine (C-C motif) ligand 20 production
Bgee · 20
TRIM32 → bronchial epithelial cell, deltoid muscle, dorsal tegmental nucleus, dorsomedial hypothalamic nucleus, gastrocnemius muscle, gonad, habenula, lobe of cerebellum, medial geniculate nucleus, muscle of thigh, piriform cortex, secondary oocyte, Skeletal muscle tissue of biceps brachii, stromal cell of endometrium, subiculum, superior colliculus, testicle, tibialis anterior muscle, ventral tegmental area, visual cortex
RNA expression pattern · 20
TRIM32 → bronchial epithelial cell, deltoid muscle, dorsal tegmental nucleus, dorsomedial hypothalamic nucleus, gastrocnemius muscle, gonad, habenula, lobe of cerebellum, medial geniculate nucleus, muscle of thigh, piriform cortex, secondary oocyte, Skeletal muscle tissue of biceps brachii, stromal cell of endometrium, subiculum, superior colliculus, testicle, tibialis anterior muscle, ventral tegmental area, visual cortex
related to Mutation-associated diseases · 14
TRIM32 → B-box, Bardet, BBS, Biedl, C-terminal NHL, D487N, D588del, LGMD2H, Limb-girdle, NHL, P130S, R394H, Specifically, T520TfsX13
related to Cancer · 10
TRIM32 → Abi2, Abl-interactor, Activated STAT, It, NF-κB, Piasy, Protein Inhibitor, Thus, TNFα, When TRIM32
related to Development · 9
TRIM32 → Ago-1, Argonaute-1, In, Let-7a, Myc, Proposed, Research, The, This
related to Mechanism · 9
TRIM32 → ABI2, Abl-interactor2, C-terminal NHL, Currently, E3, First, Myc, N-terminal RING, The
related to Skeletal muscle · 5
TRIM32 → Additionally, LGMD2H, LHMD2H-mutated TRIM32, No, The
Band · 2
TRIM32 → 4 C1|4 34.43 cM, 9q33.1
Chr. · 2
TRIM32 → Chromosome 4 (mouse), Chromosome 9 (human)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein bp piasy gene chr human band shown actin motif chromosome cancer mouse cell binding tripartite dysbindin nf-κb skeletal cells

TRIM32 relationships Subject–Predicate–Object triples

TTTA extracted 164 structured relationships around TRIM32. Examples in this analysis include TRIM32 → 2.3.2.27 → ↗ and TRIM32 → Aliases → TRIM32, BBS11, HT2A, LGMD2H, TATIP, tripartite motif containing 32, LGMDR8. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
TRIM322.3.2.271.00infobox
TRIM32AliasesTRIM32, BBS11, HT2A, LGMD2H, TATIP, tripartite motif containing 32, LGMDR81.00infobox
TRIM32Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CT2, 5FEY1.00infobox
TRIM32Band9q33.11.00infobox
TRIM32Band4 C1|4 34.43 cM1.00infobox
TRIM32Bgeestromal cell of endometrium1.00infobox
TRIM32Bgeetibialis anterior muscle1.00infobox
TRIM32Bgeegastrocnemius muscle1.00infobox
TRIM32Bgeesecondary oocyte1.00infobox
TRIM32Bgeetesticle1.00infobox
TRIM32Bgeemuscle of thigh1.00infobox
TRIM32Bgeedeltoid muscle1.00infobox
TRIM32Bgeegonad1.00infobox
TRIM32BgeeSkeletal muscle tissue of biceps brachii1.00infobox
TRIM32Bgeebronchial epithelial cell1.00infobox
TRIM32Bgeedorsomedial hypothalamic nucleus1.00infobox
TRIM32Bgeepiriform cortex1.00infobox
TRIM32Bgeehabenula1.00infobox
TRIM32Bgeeventral tegmental area1.00infobox
TRIM32Bgeesuperior colliculus1.00infobox
TRIM32Bgeesubiculum1.00infobox
TRIM32Bgeevisual cortex1.00infobox
TRIM32Bgeedorsal tegmental nucleus1.00infobox
TRIM32Bgeemedial geniculate nucleus1.00infobox
TRIM32Bgeelobe of cerebellum1.00infobox
TRIM32BioGPSMore reference expression data1.00infobox
TRIM32Chr.Chromosome 9 (human)1.00infobox
TRIM32Chr.Chromosome 4 (mouse)1.00infobox
TRIM32DatabasesNCBI: entry; OMA: entry1.00infobox
TRIM32End116,701,300 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around TRIM32 bring nearby vocabulary together. In this analysis, examples include Actin, Shown and Skeletal. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • TRIM32
    • Actin
    • Shown
    • Skeletal
    • Tripartite
    • Binding
    • Cancer
    • Cell
    • Cells
    • Piasy
    • Abi2
    • C-myc
    • Development
  • trim32
    • Actin
    • Shown
    • Skeletal
    • Tripartite
    • Binding
    • Cancer
    • Cell
    • Cells
    • Piasy
    • Abi2
    • C-myc
    • Development
  • protein
    • Tat
    • Transcription
    • Activity
    • Gene
    • Skeletal
    • Tripartite
    • Ubiquitination
    • Trim32
    • Biological
    • Structure
    • Development
    • Factor
  • gene
    • Location
    • Chromosome
    • Human
    • Tripartite
    • Bp
    • Chr
    • Structure
    • Development
    • Function
    • Muscle
    • Activity
    • Band
  • tripartite motif
    • Tripartite
    • Structure
    • Location
    • Muscle
    • Activity
    • Chromosome
    • Human
    • Skeletal
    • Bp
    • Cell
    • Chr
    • Abi2
  • actin
    • Myosin
    • Abi2
    • C-myc
    • Muscle
    • Dysbindin
    • Skeletal
    • Binding
    • Trim32
    • Piasy
    • Shown
    • Biological
    • Structure
  • skeletal muscle
    • Muscle
    • Skeletal
    • Structure
    • Location
    • Myosin
    • Activity
    • Chromosome
    • Human
    • Motif
    • Tripartite
    • Actin
    • Bp
  • function
    • Structure
    • Development
    • Location
    • Muscle
    • Activity
    • Chromosome
    • Gene
    • Human
    • Motif
    • Skeletal
    • Tripartite
    • Bp

Connections between topic areas Semantic bridges

For TRIM32, one of the stronger structural bridges in this analysis connects TRIM32 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
TRIM32Function · splits 27 ⟂ 12
TRIM32Interactions · splits 32 ⟂ 7
TRIM32Clinical significance · splits 33 ⟂ 6
TRIM32Structure · splits 34 ⟂ 5
TRIM32Subcellular distribution · splits 34 ⟂ 5
TRIM32Overview · splits 36 ⟂ 3

Map overview Semantic statistics

TRIM32

Nodes39
Edges38
Triples164
Avg. degree1.95
Density0.051282
Components1

Source & methodology

TTTA analyzes the structure around TRIM32 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — TRIM32 · EN edition · Analysis: TopicsToTalkAbout

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