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Toxication

Toxication, toxification or toxicity exaltation is the conversion of a chemical compound into a more toxic form in living organisms or in substrates such as soil or water. The conversion can be caused by enzymatic metabolism in the organisms, as well as by abiotic chemical reactions. While the parent drug is usually less active, both the parent drug and…

Toxication by enzymatic metabolism, Overview & Toxication by abiotic chemical reactions

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Toxication by enzymatic metabolism

Drug metabolismCYP450CYP2D6CYP3AHepatotoxicity
33 related topics

Overview

Chemical compoundSoilWaterEnzymaticMetabolism
16 related topics

Toxication by abiotic chemical reactions

Arsenic
1 related topics

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Overview

Toxication by enzymatic metabolism

Toxication by abiotic chemical reactions

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Map overview Semantic statistics

Toxication

Nodes54
Edges53
Triples25
Avg. degree1.96
Density0.037037
Components1

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Toxication

Top relations

related to CYP450 enzymes · 15
Toxication → Among Phase, APAP, CYP2D6, CYP2E1, CYP3A, CYP450, GSH, Hepatic, Hepatotoxicity, In, NAPQI, P450, Paracetamol, Phase, The
related to Other examples · 9
Toxication → Benzo, BP-7, Conversion, Hypoglycin, MCPA-CoA, Nicotine, NNK, NO, Other

Important terminology Word statistics

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Important terminology

toxic metabolism enzymes toxicity chemical conversion reactions abiotic organisms cyp450 drug metabolite enzymatic prodrug converted cause liver parent active generally

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
soil or waterinstance oftoxification or toxicity exaltation is the conversion of a chemical compound into a more toxic form in living organisms or in substrates0.80text
Toxicationrelated to CYP450 enzymesPhase0.60section
Toxicationrelated to CYP450 enzymesCYP4500.60section
Toxicationrelated to CYP450 enzymesThe0.60section
Toxicationrelated to CYP450 enzymesAmong Phase0.60section
Toxicationrelated to CYP450 enzymesCYP2D60.60section
Toxicationrelated to CYP450 enzymesCYP3A0.60section
Toxicationrelated to CYP450 enzymesHepatotoxicity0.60section
Toxicationrelated to CYP450 enzymesParacetamol0.60section
Toxicationrelated to CYP450 enzymesAPAP0.60section
Toxicationrelated to CYP450 enzymesNAPQI0.60section
Toxicationrelated to CYP450 enzymesP4500.60section

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