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Methoxyflurane

Methoxyflurane, sold under the brand name Penthrox (the "green whistle") among others, is an inhaled medication primarily used to reduce pain following an injury. It may also be used to reduce pain associated with minor medical procedures. Onset of pain relief is rapid and a standard dose typically lasts for up to 30 minutes. Use is only recommended with…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Consumer Drug Information
ATC code
N02BG09 (WHO)
CAS Number
76-38-0 Y
ChEBI
CHEBI:6843 N
ChEMBL
ChEMBL1341 Y

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Overview

Medical use

Side effects

Pharmacokinetics

Pharmacodynamics

Chemical properties

History

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Map overview Semantic statistics

Methoxyflurane

Nodes176
Edges175
Triples131
Avg. degree1.99
Density0.011364
Components1

How this topic connects Entity context

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Methoxyflurane

Top relations

related to history · 22
Methoxyflurane → All, Aside, Australia, Australian, Australian Defence Force, Austria, Charles, Freon, Germany, Kettering, Manhattan Project, New Zealand, New Zealand Defence Force, Plunkett, Roy, Since, St John Ambulance, Teflon, The, Thomas Midgley Jr
related to Legal status · 11
Methoxyflurane → At, European Union, In Australia, In Canada, Ireland, It, Its, New Zealand, Penthrox, United Kingdom, United States
related to Chemical properties · 10
Methoxyflurane → Applied Chemistry, Because, C3H4Cl2F2O, CHCl2CF2OCH3, International Union, It, IUPAC, MAC, Pure, With
related to Kidney · 8
Methoxyflurane → An, Another, Compared, Furthermore, MAC, Most, The, This
related to Mechanism · 7
Methoxyflurane → DCAA, It, MFAA, O-demethylation, Products, The, This
has effect · 6
Methoxyflurane → Health, MAC, Occupational Safety, The, The Australian Medicines Handbook, The National Institute
related to Medical use · 6
Methoxyflurane → Despite, Due, Each, It, Pain, The
related to Pharmacokinetics · 6
Methoxyflurane → During, Initial, It, Similar, The, This
Legal status · 5
Methoxyflurane → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), CA: ℞-only, EU: Rx-only, UK: POM (Prescription only)
related to Heart · 5
Methoxyflurane → Bleeding, In, Its, PaCO2, The

Important terminology Word statistics

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Important terminology

used pain use kidney anesthetic effects minutes medical fluorine may side time analgesic relief blood pressure analgesia penthrox volatile patients

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Methoxyflurane3D model (JSmol)Interactive image1.00infobox
MethoxyfluraneAHFS/Drugs.comConsumer Drug Information1.00infobox
MethoxyfluraneATC codeN02BG09 (WHO)1.00infobox
MethoxyfluraneCAS Number76-38-0 Y1.00infobox
MethoxyfluraneChEBICHEBI:6843 N1.00infobox
MethoxyfluraneChEMBLChEMBL1341 Y1.00infobox
MethoxyfluraneChemSpider3973 Y1.00infobox
MethoxyfluraneCompTox Dashboard (EPA)DTXSID70255561.00infobox
MethoxyfluraneDrug classVolatile anesthetic1.00infobox
MethoxyfluraneDrugBankDB01028 Y1.00infobox
MethoxyfluraneDuration of actionTypically up to 30–60 minutes depending on the frequency of breaths1.00infobox
MethoxyfluraneECHA InfoCard100.000.8701.00infobox
MethoxyfluraneFormulaC3H4Cl2F2O1.00infobox
MethoxyfluraneKEGGD00544 Y1.00infobox
MethoxyfluraneLegal statusAU: S4 (Prescription only)1.00infobox
MethoxyfluraneLegal statusBR: Class C1 (Other controlled substances)1.00infobox
MethoxyfluraneLegal statusCA: ℞-only1.00infobox
MethoxyfluraneLegal statusUK: POM (Prescription only)1.00infobox
MethoxyfluraneLegal statusEU: Rx-only1.00infobox
MethoxyfluraneMetabolism70%1.00infobox
MethoxyfluraneMolar mass164.96 g·mol−11.00infobox
MethoxyfluraneOnset of actionRapid after 6-10 breaths1.00infobox
MethoxyfluraneOther names2,2-dichloro-1,1-difluoroethyl methyl ether1.00infobox
MethoxyfluranePregnancy categoryAU: C1.00infobox
MethoxyfluranePubChem CID41161.00infobox
MethoxyfluraneRoutes of administrationInhalation1.00infobox
MethoxyfluraneTrade namesPenthrox, others1.00infobox
MethoxyfluraneUNII30905R8O7B1.00infobox
Methoxyfluranecausesa dose-dependent decrease in respiratory rate and a marked decrease in respiratory minute volume0.90text
Methoxyfluranecausesa dose-dependent decrease in tidal volume and minute volume0.90text

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