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TERF2IP: Interactions & Overview

Telomeric repeat-binding factor 2-interacting protein 1 also known as repressor activator protein 1 (Rap1) is a protein that in humans is encoded by the TERF2IP gene.

Language: English [EN]
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TERF2IP topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around TERF2IP.

Related topics
6
Source areas
2
Connected nodes
8
Extracted relationships
103
Concept neighborhoods
6
Bridge connections
8

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
TERF2IP, DRIP5, RAP1, TERF2 interacting protein
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FEX, 3K6G, 4RQI
Band
16q23.1 · 8|8 E1
Bgee
middle temporal gyrus · Brodmann area 23 · pars compacta · pars reticulata · superior vestibular nucleus
BioGPS
More reference expression data
Chr.
Chromosome 16 (human) · Chromosome 8 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How TERF2IP connects Entity context

The extracted context around TERF2IP shows recurring relationship patterns in the source. For example, TERF2IP → chromosome, cytoplasm, cytosol, DNA binding, G-rich strand telomeric DNA binding, Mre11 complex, negative regulation of DNA recombination at telomere, negative regulation of protein phosphorylation, negative regulation of telomere maintenance, nuclear body, nuclear chromosome, nuclear envelope, nuclear telomere cap complex, nucleoplasm, nucleus, phosphatase binding, positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of NF-kappaB transcription factor activity, positive regulation of NIK/NF-kappaB signaling, positive regulation of peptidyl-serine phosphorylation Another extracted example is TERF2IP → arcuate nucleus, Brodmann area 23, Brodmann area 9, dorsal tegmental nucleus, dorsomedial hypothalamic nucleus, internal globus pallidus, lateral hypothalamus, lateral nuclear group of thalamus, lumbar subsegment of spinal cord, mammillary body, middle temporal gyrus, paraventricular nucleus of hypothalamus, pars compacta, pars reticulata, pons, superior frontal gyrus, superior vestibular nucleus, supraoptic nucleus, ventral tegmental area, ventromedial nucleus. Use these groups to spot repeated connection types before inspecting the individual relationships.

TERF2IP

Top relations

Gene ontology · 35
TERF2IP → chromosome, cytoplasm, cytosol, DNA binding, G-rich strand telomeric DNA binding, Mre11 complex, negative regulation of DNA recombination at telomere, negative regulation of protein phosphorylation, negative regulation of telomere maintenance, nuclear body, nuclear chromosome, nuclear envelope, nuclear telomere cap complex, nucleoplasm, nucleus, phosphatase binding, positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of NF-kappaB transcription factor activity, positive regulation of NIK/NF-kappaB signaling, positive regulation of peptidyl-serine phosphorylation
Bgee · 20
TERF2IP → arcuate nucleus, Brodmann area 23, Brodmann area 9, dorsal tegmental nucleus, dorsomedial hypothalamic nucleus, internal globus pallidus, lateral hypothalamus, lateral nuclear group of thalamus, lumbar subsegment of spinal cord, mammillary body, middle temporal gyrus, paraventricular nucleus of hypothalamus, pars compacta, pars reticulata, pons, superior frontal gyrus, superior vestibular nucleus, supraoptic nucleus, ventral tegmental area, ventromedial nucleus
RNA expression pattern · 20
TERF2IP → arcuate nucleus, Brodmann area 23, Brodmann area 9, dorsal tegmental nucleus, dorsomedial hypothalamic nucleus, internal globus pallidus, lateral hypothalamus, lateral nuclear group of thalamus, lumbar subsegment of spinal cord, mammillary body, middle temporal gyrus, paraventricular nucleus of hypothalamus, pars compacta, pars reticulata, pons, superior frontal gyrus, superior vestibular nucleus, supraoptic nucleus, ventral tegmental area, ventromedial nucleus
related to Interactions · 5
TERF2IP → Ku80, Rad50, TERF2, TERF2IP/TERF2, Upon
Band · 2
TERF2IP → 16q23.1, 8|8 E1
Chr. · 2
TERF2IP → Chromosome 16 (human), Chromosome 8 (mouse)
End · 2
TERF2IP → 112,747,160 bp, 75,761,872 bp
Aliases · 1
TERF2IP → TERF2IP, DRIP5, RAP1, TERF2 interacting protein
Available structures · 1
TERF2IP → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FEX, 3K6G, 4RQI
BioGPS · 1
TERF2IP → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp chr human chromosome band gene 16 protein telomeric location terf2 mouse factor rap1 search 761 872 end 75 747

TERF2IP relationships Subject–Predicate–Object triples

TTTA extracted 103 structured relationships around TERF2IP. Examples in this analysis include TERF2IP → Aliases → TERF2IP, DRIP5, RAP1, TERF2 interacting protein and TERF2IP → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FEX, 3K6G, 4RQI. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
TERF2IPAliasesTERF2IP, DRIP5, RAP1, TERF2 interacting protein1.00infobox
TERF2IPAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FEX, 3K6G, 4RQI1.00infobox
TERF2IPBand16q23.11.00infobox
TERF2IPBand8|8 E11.00infobox
TERF2IPBgeemiddle temporal gyrus1.00infobox
TERF2IPBgeeBrodmann area 231.00infobox
TERF2IPBgeepars compacta1.00infobox
TERF2IPBgeepars reticulata1.00infobox
TERF2IPBgeesuperior vestibular nucleus1.00infobox
TERF2IPBgeepons1.00infobox
TERF2IPBgeeinternal globus pallidus1.00infobox
TERF2IPBgeelateral nuclear group of thalamus1.00infobox
TERF2IPBgeeBrodmann area 91.00infobox
TERF2IPBgeesuperior frontal gyrus1.00infobox
TERF2IPBgeeventromedial nucleus1.00infobox
TERF2IPBgeesupraoptic nucleus1.00infobox
TERF2IPBgeeparaventricular nucleus of hypothalamus1.00infobox
TERF2IPBgeedorsomedial hypothalamic nucleus1.00infobox
TERF2IPBgeelateral hypothalamus1.00infobox
TERF2IPBgeelumbar subsegment of spinal cord1.00infobox
TERF2IPBgeeventral tegmental area1.00infobox
TERF2IPBgeearcuate nucleus1.00infobox
TERF2IPBgeedorsal tegmental nucleus1.00infobox
TERF2IPBgeemammillary body1.00infobox
TERF2IPBioGPSMore reference expression data1.00infobox
TERF2IPChr.Chromosome 16 (human)1.00infobox
TERF2IPChr.Chromosome 8 (mouse)1.00infobox
TERF2IPDatabasesNCBI: entry; OMA: entry1.00infobox
TERF2IPEnd75,761,872 bp1.00infobox
TERF2IPEnd112,747,160 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around TERF2IP bring nearby vocabulary together. In this analysis, examples include Protein, Telomeric and Terf2. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • TERF2IP
    • Protein
    • Telomeric
    • Terf2
    • Gene
    • Complex
    • Factor
    • Rap1
    • Search
    • Shown
    • Location
    • Chromosome
    • Human
  • terf2ip
    • Protein
    • Telomeric
    • Terf2
    • Gene
    • Complex
    • Factor
    • Rap1
    • Search
    • Shown
    • Location
    • Chromosome
    • Human
  • protein
    • Gene
    • Terf2ip
    • Rap1
    • Search
    • Location
    • Telomeric
    • Terf2
    • Chromosome
    • Human
    • Activator
    • Also
    • Bp
  • gene
    • Location
    • Protein
    • Chromosome
    • Human
    • Terf2ip
    • Bp
    • Chr
    • End
    • Mouse
    • Rap1
    • Search
    • Telomeric
  • interactions
    • Reading
    • References
    • Rap1
    • Search
    • Location
    • Protein
    • Terf2
    • Chromosome
    • Human
    • Terf2ip
    • Bp
    • Chr
  • terf2
    • Terf2ip
    • Complex
    • Search
    • Shown
    • End
    • Mouse
    • Band

Connections between topic areas Semantic bridges

For TERF2IP, one of the stronger structural bridges in this analysis connects TERF2IP with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
TERF2IPInteractions · splits 4 ⟂ 5
TERF2IPOverview · splits 6 ⟂ 3

Map overview Semantic statistics

TERF2IP

Nodes9
Edges8
Triples103
Avg. degree1.78
Density0.222222
Components1

Source & methodology

TTTA analyzes the structure around TERF2IP to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — TERF2IP · EN edition · Analysis: TopicsToTalkAbout

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