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IFNAR1: Function, Interactions & Overview

Interferon-alpha/beta receptor alpha chain is a protein that in humans is encoded by the IFNAR1 gene.

Language: English [EN]
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IFNAR1 topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around IFNAR1.

Related topics
10
Source areas
3
Connected nodes
13
Extracted relationships
82
Concept neighborhoods
10
Bridge connections
13

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 5 topics
Interactions · 3 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
IFNAR1, AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC, interferon alpha and beta receptor subunit 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3S98, 3SE3, 3SE4, 4PO6
Band
21q22.11 · 16 C3.3|16 52.98 cM
Bgee
monocyte · rectum · gallbladder · ventricular zone · islet of Langerhans
BioGPS
More reference expression data
Chr.
Chromosome 21 (human) · Chromosome 16 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How IFNAR1 connects Entity context

The extracted context around IFNAR1 shows recurring relationship patterns in the source. For example, IFNAR1 → Achilles tendon, aortic valve, blood, cumulus cell, endothelial cell, epithelium of colon, gallbladder, genital tubercle, granulocyte, islet of Langerhans, monocyte, rectum, Rostral migratory stream, stroma of bone marrow, stromal cell of endometrium, tail of embryo, thymus, vas deferens, ventricular zone Another extracted example is IFNAR1 → cellular response to interferon-alpha, cytokine receptor activity, cytokine-mediated signaling pathway, endosome, integral component of membrane, integral component of plasma membrane, interferon receptor activity, interleukin-10 receptor activity, late endosome, lysosome, membrane, plasma membrane, protein binding, receptor signaling pathway via JAK-STAT, response to lipopolysaccharide, response to virus, type I interferon binding, type I interferon receptor activity, type I interferon signaling pathway. Use these groups to spot repeated connection types before inspecting the individual relationships.

IFNAR1

Top relations

Bgee · 19
IFNAR1 → Achilles tendon, aortic valve, blood, cumulus cell, endothelial cell, epithelium of colon, gallbladder, genital tubercle, granulocyte, islet of Langerhans, monocyte, rectum, Rostral migratory stream, stroma of bone marrow, stromal cell of endometrium, tail of embryo, thymus, vas deferens, ventricular zone
Gene ontology · 19
IFNAR1 → cellular response to interferon-alpha, cytokine receptor activity, cytokine-mediated signaling pathway, endosome, integral component of membrane, integral component of plasma membrane, interferon receptor activity, interleukin-10 receptor activity, late endosome, lysosome, membrane, plasma membrane, protein binding, receptor signaling pathway via JAK-STAT, response to lipopolysaccharide, response to virus, type I interferon binding, type I interferon receptor activity, type I interferon signaling pathway
RNA expression pattern · 19
IFNAR1 → Achilles tendon, aortic valve, blood, cumulus cell, endothelial cell, epithelium of colon, gallbladder, genital tubercle, granulocyte, islet of Langerhans, monocyte, rectum, Rostral migratory stream, stroma of bone marrow, stromal cell of endometrium, tail of embryo, thymus, vas deferens, ventricular zone
Band · 2
IFNAR1 → 16 C3.3|16 52.98 cM, 21q22.11
Chr. · 2
IFNAR1 → Chromosome 16 (mouse), Chromosome 21 (human)
End · 2
IFNAR1 → 33,359,864 bp, 91,304,329 bp
related to Interactions · 2
IFNAR1 → PRMT1, STAT2
Aliases · 1
IFNAR1 → IFNAR1, AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC, interferon alpha and beta receptor subunit 1
Available structures · 1
IFNAR1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3S98, 3SE3, 3SE4, 4PO6
BioGPS · 1
IFNAR1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr human band receptor protein chromosome 21 interferon-alpha location encoded mouse beta alpha function interferon search 359 864

IFNAR1 relationships Subject–Predicate–Object triples

TTTA extracted 82 structured relationships around IFNAR1. Examples in this analysis include IFNAR1 → Aliases → IFNAR1, AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC, interferon alpha and beta receptor subunit 1 and IFNAR1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3S98, 3SE3, 3SE4, 4PO6. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
IFNAR1AliasesIFNAR1, AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC, interferon alpha and beta receptor subunit 11.00infobox
IFNAR1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3S98, 3SE3, 3SE4, 4PO61.00infobox
IFNAR1Band21q22.111.00infobox
IFNAR1Band16 C3.3|16 52.98 cM1.00infobox
IFNAR1Bgeemonocyte1.00infobox
IFNAR1Bgeerectum1.00infobox
IFNAR1Bgeegallbladder1.00infobox
IFNAR1Bgeeventricular zone1.00infobox
IFNAR1Bgeeislet of Langerhans1.00infobox
IFNAR1Bgeeendothelial cell1.00infobox
IFNAR1BgeeAchilles tendon1.00infobox
IFNAR1Bgeeblood1.00infobox
IFNAR1Bgeeepithelium of colon1.00infobox
IFNAR1Bgeestromal cell of endometrium1.00infobox
IFNAR1Bgeegenital tubercle1.00infobox
IFNAR1Bgeetail of embryo1.00infobox
IFNAR1Bgeegranulocyte1.00infobox
IFNAR1BgeeRostral migratory stream1.00infobox
IFNAR1Bgeevas deferens1.00infobox
IFNAR1Bgeeaortic valve1.00infobox
IFNAR1Bgeestroma of bone marrow1.00infobox
IFNAR1Bgeecumulus cell1.00infobox
IFNAR1Bgeethymus1.00infobox
IFNAR1BioGPSMore reference expression data1.00infobox
IFNAR1Chr.Chromosome 21 (human)1.00infobox
IFNAR1Chr.Chromosome 16 (mouse)1.00infobox
IFNAR1DatabasesNCBI: entry; OMA: entry1.00infobox
IFNAR1End33,359,864 bp1.00infobox
IFNAR1End91,304,329 bp1.00infobox
IFNAR1EnsemblENSG000001421661.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around IFNAR1 bring nearby vocabulary together. In this analysis, examples include Gene, Receptor and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • IFNAR1
    • Gene
    • Receptor
    • Function
    • Interferon
    • Interferon-alpha
    • Search
    • Location
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
  • ifnar1
    • Gene
    • Receptor
    • Function
    • Interferon
    • Interferon-alpha
    • Search
    • Location
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
  • gene
    • Location
    • Chromosome
    • Human
    • Ifnar1
    • Receptor
    • Bp
    • C3
    • Chr
    • End
    • Function
    • Interferon
    • Interferon-alpha
  • type i membrane protein
    • Membrane
    • Type
    • Receptor
    • Binding
    • C3
    • End
    • Function
    • Including
    • Interferon
    • Interferon-alpha
    • Mouse
    • Search
  • function
    • Interferon
    • Search
    • Location
    • Chromosome
    • Gene
    • Human
    • Ifnar1
    • Interactions
    • Membrane
    • Reading
    • Receptor
    • References
  • type i interferons
    • Membrane
    • Binding
    • C3
    • End
    • Function
    • Including
    • Interferon
    • Interferon-alpha
    • Mouse
    • Search
    • Encoded
    • Location
  • protein
    • Receptor
    • Binding
    • Including
    • Membrane
    • Type
    • C3
    • End
    • Function
    • Interferon
    • Mouse
    • Search
    • Stat2
  • janus protein kinases
    • Receptor
    • Binding
    • Including
    • Membrane
    • Type
    • C3
    • End
    • Function
    • Interferon
    • Mouse
    • Search
    • Stat2

Connections between topic areas Semantic bridges

For IFNAR1, one of the stronger structural bridges in this analysis connects IFNAR1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
IFNAR1Function · splits 8 ⟂ 6
IFNAR1Interactions · splits 10 ⟂ 4
IFNAR1Overview · splits 11 ⟂ 3

Map overview Semantic statistics

IFNAR1

Nodes14
Edges13
Triples82
Avg. degree1.86
Density0.142857
Components1

Source & methodology

TTTA analyzes the structure around IFNAR1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — IFNAR1 · EN edition · Analysis: TopicsToTalkAbout

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