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Senescence

Senescence (/ˌsɪˈnɛsəns/) or biological aging is the gradual deterioration of functional characteristics in living organisms. Whole organism senescence involves an increase in death rates or a decrease in fecundity with increasing age, at least in the later part of an organism's life cycle. However, the effects of senescence can be delayed. The 1934…

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Overview

Definition and characteristics

Variation among species

Theories of aging

Biomarkers of aging

Genetic determinants of aging

Healthspans and aging in society

Interventions

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Map overview Semantic statistics

Senescence

Nodes238
Edges237
Triples52
Avg. degree1.99
Density0.008403
Components1

How this topic connects Entity context

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Senescence

Top relations

related to Variation among species · 10
Senescence → Almost, Different, For, Hydra, Organisms, Planarian, The, There, These, Turritopsis
related to Stem cell theories of aging · 8
Senescence → Balancing, Damage, In, Maintaining, See, Stem, The, These
related to Definition and characteristics · 5
Senescence → Actuarial, Aging, Makeham, Organismal, The Gompertz
see also · 3
Senescence → Anti-aging, SENS, Sub-lethal
is a · 1
Senescence → aging of whole organisms

Important terminology Word statistics

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Important terminology

aging age dna cells may damage theories life stem species also theory including process organisms human selection different cell proteins

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Senescenceis aaging of whole organisms0.90text
members of the genus Hydra have motivated research into delaying senescenceinstance ofand the existence of potentially immortal organisms0.80text
thus age-related diseasesinstance ofand the existence of potentially immortal organisms0.80text
gene regulationinstance ofThe molecular theories of ageing include phenomena0.80text
oxygeninstance ofcaused by ubiquitous chemical agents in the body0.80text
sugarsinstance ofcaused by ubiquitous chemical agents in the body0.80text
are in part responsible for aginginstance ofcaused by ubiquitous chemical agents in the body0.80text
guanine to produce sugar adductsinstance ofglucose metabolism and AMPK.Sugars such as glucose and fructose can react with certain amino acids such as lysine and arginine and certain DNA bases0.80text
in a process called glycationinstance ofglucose metabolism and AMPK.Sugars such as glucose and fructose can react with certain amino acids such as lysine and arginine and certain DNA bases0.80text
non-structural proteinsinstance ofwhich can then cross-link the structural proteins or DNA to similar biopolymers or other biomolecules0.80text
predationinstance ofAge-independent hazards0.80text
diseaseinstance ofAge-independent hazards0.80text

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