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Inflammaging

Inflammaging (also known as inflamm-aging or inflamm-ageing) is a chronic, sterile, low-grade inflammation that develops with advanced age, in the absence of overt infection, and may contribute to clinical manifestations of other age-related pathologies. Inflammaging is thought to be caused by a loss of control over systemic inflammation resulting in…

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Overview

Characteristics

Causes

Biomarkers of inflammaging

Evolutionary consideration

Inflammaging and COVID-19

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Map overview Semantic statistics

Inflammaging

Nodes68
Edges67
Triples71
Avg. degree1.97
Density0.029412
Components1

How this topic connects Entity context

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Inflammaging

Top relations

related to Inflammaging and COVID-19 · 14
Inflammaging → Adaptive, Alzheimers, Amyotrophic, Available, Chronic, COVID-19, For, H1N1, Infection, Parkinson's, SARS-CoV2, This, Viral, While
related to Biomarkers of inflammaging · 11
Inflammaging → Aging, Altogether, Biomarkers, CD4/CD8, Currently, Cytokines, IL-1, IL-6, SASP, The, TNF
related to Inflammasome activation · 10
Inflammaging → DAMPS, Examples, Over-activation, PAMPS, Pro-inflammatory, Receptors, Stimuli, The, These, When
related to Characteristics · 7
Inflammaging → All, Fine, MSCs, Remodeling, The, While, With
related to Evolutionary consideration · 7
Inflammaging → Additionally, In, Inflammation, It, Perhaps, This, While
related to SASP phenotype · 5
Inflammaging → Cells, SASP, Senescent, These, This
related to Tumor necrosis factor · 5
Inflammaging → Additionally, TNF, TNF Receptor, Tumor, With
related to Functional decline in autophagy and mitophagy · 3
Inflammaging → Another, As, This
is a · 2
Inflammaging → decline in effective autophagy and mitophagy capacity, significant risk factor in mortality and morbidity in aged individuals.Inflammation is essential to protect against viral and bacterial infection

Important terminology Word statistics

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Important terminology

inflammation immune age inflammatory system infection chronic inflammasome tnf may contribute diseases pro-inflammatory cells cell cytokine secretion viral biomarkers factors

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Inflammagingis asignificant risk factor in mortality and morbidity in aged individuals.Inflammation is essential to protect against viral and bacterial infection0.90text
Inflammagingis adecline in effective autophagy and mitophagy capacity0.90text
genesinstance ofand factors0.80text
lifestyleinstance ofand factors0.80text
and environment contribute to these changesinstance ofand factors0.80text
the lungsinstance ofThis cytokine has been identified in many organs0.80text
adipose tissueinstance ofThis cytokine has been identified in many organs0.80text
muscleinstance ofThis cytokine has been identified in many organs0.80text
and braininstance ofThis cytokine has been identified in many organs0.80text
Inflammagingrelated to Biomarkers of inflammagingCytokines0.60section
Inflammagingrelated to Biomarkers of inflammagingAging0.60section
Inflammagingrelated to Biomarkers of inflammagingCurrently0.60section

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