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Semaphorin: Regions, Classes & Functions

Semaphorins are a class of secreted and membrane proteins that were originally identified as axonal growth cone guidance molecules. They primarily act as short-range inhibitory signals and signal through multimeric receptor complexes. Semaphorins are usually cues to deflect axons from inappropriate regions, especially important in the neural system…

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Semaphorin topic overview

The analysis highlights Regions, Classes and Functions as prominent areas in the source structure around Semaphorin.

Related topics
37
Source areas
4
Connected nodes
41
Extracted relationships
27
Concept neighborhoods
17
Bridge connections
41

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Classes · 17 topics
Overview · 12 topics
Functions · 6 topics
Semaphorin receptors · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR027231
Available protein structures:
IPR027231
CDD
cd04979
InterPro
IPR027231
Membranome
71
PDB
IPR027231

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Classes

Semaphorin receptors

Functions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Semaphorin connects Entity context

The extracted context around Semaphorin shows recurring relationship patterns in the source. For example, Semaphorin → Class, During, For, Sema3a, Semaphorins, Their, They Another extracted example is Semaphorin → Class, Different, Most Semaphorins, Plexins, Semaphorins. Use these groups to spot repeated connection types before inspecting the individual relationships.

Semaphorin

Top relations

related to Functions · 7
Semaphorin → Class, During, For, Sema3a, Semaphorins, Their, They
related to Semaphorin receptors · 5
Semaphorin → Class, Different, Most Semaphorins, Plexins, Semaphorins
related to Classes · 4
Semaphorin → Class, Classes, The, The Semaphorins
related to External links · 4
Semaphorin → Medicine Medical Subject Headings, MeSH, National Library, Semaphorins
AlphaFold · 1
Semaphorin → IPR027231
Available protein structures: · 1
Semaphorin → IPR027231
CDD · 1
Semaphorin → cd04979
InterPro · 1
Semaphorin → IPR027231
Membranome · 1
Semaphorin → 71
PDB · 1
Semaphorin → IPR027231

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

semaphorins class plexins receptors classes proteins sema3a axons molecules system development major many specific act called axonal neuropilins integrins invertebrates

Semaphorin relationships Subject–Predicate–Object triples

TTTA extracted 27 structured relationships around Semaphorin. Examples in this analysis include Semaphorin → AlphaFold → IPR027231 and Semaphorin → CDD → cd04979. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SemaphorinAlphaFoldIPR0272311.00infobox
SemaphorinAvailable protein structures:IPR0272311.00infobox
SemaphorinCDDcd049791.00infobox
SemaphorinInterProIPR0272311.00infobox
SemaphorinMembranome711.00infobox
SemaphorinPDBIPR0272311.00infobox
SemaphorinSymbolSemaphorin1.00infobox
Semaphorinrelated to ClassesThe Semaphorins0.60section
Semaphorinrelated to ClassesThe0.60section
Semaphorinrelated to ClassesClasses0.60section
Semaphorinrelated to ClassesClass0.60section
Semaphorinrelated to External linksSemaphorins0.60section

Related concept clusters Concept neighborhoods

The concept neighborhoods around Semaphorin bring nearby vocabulary together. In this analysis, examples include Classes, Different and Specific. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • proteins
    • Secreted
    • Plexins
    • Receptors
    • Act
    • Axonal
    • Called
    • Group
    • Guidance
    • Neuropilins
    • Sema3g
    • Different
    • Major
  • plexins
    • Neuropilins
    • Receptors
    • Different
    • Proteins
    • Gtpases
    • R-ras
    • Semaphorins
    • Also
    • Group
    • Integrins
    • Regulate
    • Roles
  • classes
    • Invertebrates
    • Major
    • Vertebrates
    • Semaphorin
    • Membrane
    • Roles
    • Secreted
    • Development
    • Specific
    • Proteins
    • Sema3a
    • Semaphorins
  • semaphorin receptors
    • Semaphorins
    • Classes
    • Semaphorin
    • Gtpases
    • Group
    • Integrins
    • Roles
    • Sema3g
    • Different
    • Specific
    • Sema3a
  • axonal
    • Guidance
    • Membrane
    • Secreted
    • Molecules
    • System
    • Proteins
    • Class
    • Semaphorins
  • neuropilins
    • Plexins
    • Signal
    • Signals
    • Different
    • Many
    • Proteins
    • Receptors
    • Semaphorins
  • neural system
    • Important
    • Cues
    • Axonal
    • Development
    • Semaphorins
    • Axons
    • Class
  • central nervous system
    • Important
    • Cues
    • Axonal
    • Development
    • Semaphorins
    • Axons
    • Class

Connections between topic areas Semantic bridges

For Semaphorin, one of the stronger structural bridges in this analysis connects Semaphorin with Classes. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Semaphorin — Classes · splits 24 ⟂ 18
Semaphorin — Overview · splits 29 ⟂ 13
Semaphorin — Functions · splits 35 ⟂ 7
Semaphorin — Semaphorin receptors · splits 39 ⟂ 3

Map overview Semantic statistics

Semaphorin

Nodes42
Edges41
Triples27
Avg. degree1.95
Density0.047619
Components1

Source & methodology

TTTA analyzes the structure around Semaphorin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Classes & Functions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Semaphorin · EN edition · Analysis: TopicsToTalkAbout

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