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SEMA7A: Development & Overview

Semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) (SEMA7A) also known as CD108 (Cluster of Differentiation 108), is a human gene.

Language: English [EN]
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SEMA7A topic overview

The analysis highlights Development and Overview as prominent areas in the source structure around SEMA7A.

Related topics
5
Source areas
2
Connected nodes
7
Extracted relationships
111
Related term clusters
5
Bridge connections
7

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 4 topics
Development · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SEMA7A, CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, SEMAK1, SEMAL, semaphorin 7A (John Milton Hagen blood group), PFIC11
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3NVQ
Band
15q24.1 · 9|9 B
Bgee
spleen · C1 segment · primary visual cortex · placenta · right hemisphere of cerebellum
BioGPS
More reference expression data
Chr.
Chromosome 15 (human) · Chromosome 9 (mouse)

Start with your topic. Discover where to go next.

Explore different angles and find fresh ideas to shape your next piece of content.

SEMA7A
3Semaphorin · Lymphocytes · Erythrocytes

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Development

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How SEMA7A connects Entity context

The extracted context around SEMA7A shows recurring relationship patterns in the source. For example, SEMA7A → anchored component of membrane, axon extension, cell differentiation, chemorepellent activity, collagen-containing extracellular matrix, external side of plasma membrane, extracellular space, immune response, inflammatory response, integral component of plasma membrane, integrin binding, integrin-mediated signaling pathway, membrane, multicellular organism development, negative chemotaxis, negative regulation of axon extension involved in axon guidance, nervous system development, neural crest cell migration, neuron projection development, neuropilin binding Another extracted example is SEMA7A → anterior horn of spinal cord, Brodmann area 9, C1 segment, cerebellar cortex, cumulus cell, dentate gyrus of hippocampal formation granule cell, lateral geniculate nucleus, lobe of cerebellum, lumbar subsegment of spinal cord, placenta, prefrontal cortex, primary motor cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, spleen, stromal cell of endometrium, superior frontal gyrus. Use these groups to spot repeated connection types before inspecting the individual relationships.

SEMA7A

Top relations

Gene ontology · 32
SEMA7A → anchored component of membrane, axon extension, cell differentiation, chemorepellent activity, collagen-containing extracellular matrix, external side of plasma membrane, extracellular space, immune response, inflammatory response, integral component of plasma membrane, integrin binding, integrin-mediated signaling pathway, membrane, multicellular organism development, negative chemotaxis, negative regulation of axon extension involved in axon guidance, nervous system development, neural crest cell migration, neuron projection development, neuropilin binding
Bgee · 18
SEMA7A → anterior horn of spinal cord, Brodmann area 9, C1 segment, cerebellar cortex, cumulus cell, dentate gyrus of hippocampal formation granule cell, lateral geniculate nucleus, lobe of cerebellum, lumbar subsegment of spinal cord, placenta, prefrontal cortex, primary motor cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, spleen, stromal cell of endometrium, superior frontal gyrus
RNA expression pattern · 18
SEMA7A → anterior horn of spinal cord, Brodmann area 9, C1 segment, cerebellar cortex, cumulus cell, dentate gyrus of hippocampal formation granule cell, lateral geniculate nucleus, lobe of cerebellum, lumbar subsegment of spinal cord, placenta, prefrontal cortex, primary motor cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, spleen, stromal cell of endometrium, superior frontal gyrus
related to Development · 5
SEMA7A → Embryonic Sema7A, Limited, Murine, T-cell, Unlike
related to Tumorigenesis · 4
SEMA7A → EMT, Increased SEMA7A, Tumor, Tumors
Band · 2
SEMA7A → 15q24.1, 9|9 B
Chr. · 2
SEMA7A → Chromosome 15 (human), Chromosome 9 (mouse)
End · 2
SEMA7A → 57,870,148 bp, 74,433,958 bp
Aliases · 1
SEMA7A → SEMA7A, CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, SEMAK1, SEMAL, semaphorin 7A (John Milton Hagen blood group), PFIC11
Available structures · 1
SEMA7A → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3NVQ

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human bp expression gene semaphorin chr band differentiation blood group chromosome 15 also development known external mouse john milton hagen

SEMA7A relationships Subject–Predicate–Object triples

TTTA extracted 111 structured relationships around SEMA7A. Examples in this analysis include SEMA7A → Aliases → SEMA7A, CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, SEMAK1, SEMAL, semaphorin 7A (John Milton Hagen blood group), PFIC11 and SEMA7A → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3NVQ. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SEMA7AAliasesSEMA7A, CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, SEMAK1, SEMAL, semaphorin 7A (John Milton Hagen blood group), PFIC111.00infobox
SEMA7AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3NVQ1.00infobox
SEMA7ABand15q24.11.00infobox
SEMA7ABand9|9 B1.00infobox
SEMA7ABgeespleen1.00infobox
SEMA7ABgeeC1 segment1.00infobox
SEMA7ABgeeprimary visual cortex1.00infobox
SEMA7ABgeeplacenta1.00infobox
SEMA7ABgeeright hemisphere of cerebellum1.00infobox
SEMA7ABgeeprefrontal cortex1.00infobox
SEMA7ABgeestromal cell of endometrium1.00infobox
SEMA7ABgeesuperior frontal gyrus1.00infobox
SEMA7ABgeeBrodmann area 91.00infobox
SEMA7ABgeeright frontal lobe1.00infobox
SEMA7ABgeecumulus cell1.00infobox
SEMA7ABgeecerebellar cortex1.00infobox
SEMA7ABgeelumbar subsegment of spinal cord1.00infobox
SEMA7ABgeeanterior horn of spinal cord1.00infobox
SEMA7ABgeedentate gyrus of hippocampal formation granule cell1.00infobox
SEMA7ABgeeprimary motor cortex1.00infobox
SEMA7ABgeelateral geniculate nucleus1.00infobox
SEMA7ABgeelobe of cerebellum1.00infobox
SEMA7ABioGPSMore reference expression data1.00infobox
SEMA7AChr.Chromosome 15 (human)1.00infobox
SEMA7AChr.Chromosome 9 (mouse)1.00infobox
SEMA7ADatabasesNCBI: entry; OMA: entry1.00infobox
SEMA7AEnd74,433,958 bp1.00infobox
SEMA7AEnd57,870,148 bp1.00infobox
SEMA7AEnsemblENSG00000138623 ENSG000002884551.00infobox
SEMA7AEntrez84821.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around SEMA7A bring nearby vocabulary together. In this analysis, examples include Expression, Differentiation and Development. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • SEMA7A
    • Expression
    • Differentiation
    • Development
    • Semaphorin
    • Human
    • Adult
    • Also
    • Cell
    • Embryonic
    • Expressed
    • Growth
    • Gene
  • sema7a
    • Expression
    • Differentiation
    • Development
    • Semaphorin
    • Human
    • Adult
    • Also
    • Cell
    • Embryonic
    • Expressed
    • Growth
    • Gene
  • gene
    • Human
    • Hagen
    • John
    • Location
    • Milton
    • Chromosome
    • Group
    • Semaphorin
    • Bp
    • Chr
    • External
    • Membrane
  • development
    • External
    • Molecular
    • Location
    • Chromosome
    • Semaphorin
    • Bp
    • Chr
    • Gene
    • Sema7a
    • Human
    • Expression
    • Formation
  • semaphorin
    • Spleen

Connections between topic areas Semantic bridges

For SEMA7A, one of the stronger structural bridges in this analysis connects SEMA7A with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SEMA7A — Overview · splits 3 ⟂ 5

Map overview Semantic statistics

SEMA7A

Nodes8
Edges7
Triples111
Avg. degree1.75
Density0.25
Components1

Source & methodology

TTTA analyzes the structure around SEMA7A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Development & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SEMA7A · EN edition · Analysis: TopicsToTalkAbout

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