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Selectin: Research, Function & Types

The selectins (cluster of differentiation 62 or CD62) are a family of cell adhesion molecules (or CAMs). All selectins are single-chain transmembrane glycoproteins that share similar properties to C-type lectins due to a related amino terminus and calcium-dependent binding. Selectins bind to sugar moieties and so are considered to be a type of lectin…

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Selectin topic overview

The analysis highlights Research, Function and Types as prominent areas in the source structure around Selectin.

Related topics
34
Source areas
8
Connected nodes
42
Extracted relationships
71
Concept neighborhoods
14
Bridge connections
42

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 9 topics
Function · 8 topics
Types · 7 topics
Research · 5 topics
Role in cancer · 2 topics
Bonding mechanisms · 1 topics
Etymology · 1 topics
Structure · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR002396
Available protein structures:
IPR002396
InterPro
IPR002396
Membranome
12
PDB
IPR002396
Symbol
Selectin

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Types

Etymology

Function

Bonding mechanisms

Role in cancer

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Selectin connects Entity context

The extracted context around Selectin shows recurring relationship patterns in the source. For example, Selectin → ICAM, Ig-CAM, In, Metastatic, Moreover, Several, The, This, Typically Another extracted example is Selectin → Cytokines, During, E-selectin, P-selectin, Selectins, Stimuli, TNF-alpha, Weible-Palade. Use these groups to spot repeated connection types before inspecting the individual relationships.

Selectin

Top relations

related to Organ selectivity · 9
Selectin → ICAM, Ig-CAM, In, Metastatic, Moreover, Several, The, This, Typically
related to Function · 8
Selectin → Cytokines, During, E-selectin, P-selectin, Selectins, Stimuli, TNF-alpha, Weible-Palade
related to Structure · 7
Selectin → All, EGF, N-terminal, P-selectin, The, Though, TM
related to Role in cancer · 6
Selectin → E-selectin, In, It, L-selectin, P-selectin, Tumor
related to Bonding mechanisms · 5
Selectin → In, Lewis, PSGL-1, Selectins, Shear
related to Research · 5
Selectin → E-selectins, Osteoblasts, Researchers, Selectins, Thus
related to External links · 4
Selectin → P-selectin, Research Archived, Sackstein Lab, Wayback MachineComputer-generated
related to Types · 4
Selectin → E-selectin, L-selectin, P-selectin, There
is a · 2
Selectin → sialylated Lewis X antigen, smallest of the vascular selectins
AlphaFold · 1
Selectin → IPR002396

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

selectins cells p-selectin endothelial e-selectin cancer binding bind cell expressed adhesion lectin metastasis ligands may organ expression transmembrane similar structure

Selectin relationships Subject–Predicate–Object triples

TTTA extracted 71 structured relationships around Selectin. Examples in this analysis include Selectin → AlphaFold → IPR002396 and Selectin → Membranome → 12. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SelectinAlphaFoldIPR0023961.00infobox
SelectinAvailable protein structures:IPR0023961.00infobox
SelectinInterProIPR0023961.00infobox
SelectinMembranome121.00infobox
SelectinPDBIPR0023961.00infobox
SelectinSymbolSelectin1.00infobox
Selectinis asmallest of the vascular selectins0.90text
Selectinis asialylated Lewis X antigen0.90text
histamineinstance ofStimuli0.80text
thrombin cause endothelial cells to mobilize immediate release of preformed P-selectin from Weible-Palade bodies inside the cellinstance ofStimuli0.80text
TNF-alpha stimulate transcriptioninstance ofCytokines0.80text
translation of E-selectininstance ofCytokines0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Selectin bring nearby vocabulary together. In this analysis, examples include Domain, Lewis and Cells. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Selectin
    • Domain
    • Lewis
    • Cells
    • Specific
    • Endothelial
    • Carbohydrate
    • Leukocyte
    • Expression
    • Ligands
    • May
    • Selectins
    • E-selectin
  • selectin
    • Domain
    • Lewis
    • Cells
    • Specific
    • Endothelial
    • Carbohydrate
    • Leukocyte
    • Expression
    • Ligands
    • May
    • Selectins
    • E-selectin
  • cell adhesion
    • Expression
    • Molecules
    • Several
    • Cancer
    • Carbohydrate
    • Rolling
    • Adhesion
    • Cell
    • Selectins
    • Endothelial
    • Cells
    • Sugar
  • p-selectin
    • E-selectin
    • Cells
    • Expressed
    • Endothelial
    • Leukocytes
    • Three
    • Selectin
    • Structure
    • Cytokines
    • Different
    • Role
    • Structures
  • stem cells
    • Endothelial
    • Expressed
    • Expression
    • P-selectin
    • Selectins
    • E-selectin
    • Ligands
    • Specific
    • Surface
    • Vascular
    • Carbohydrate
    • Rolling
  • role in cancer
    • Endothelial
    • Expression
    • Cells
    • Cancer
    • Role
    • Metastasis
    • Organ
    • Structure
    • May
    • Expressed
    • Sugar
    • E-selectin
  • leukocyte adhesion cascade
    • Expression
    • Molecules
    • Rolling
    • Several
    • Cancer
    • Cell
    • Selectins
    • Endothelial
    • Leukocytes
    • Sugar
    • Vascular
    • Cells
  • e-selectin
    • P-selectin
    • Expressed
    • Cytokines
    • Leukocytes
    • Ligands
    • Endothelial
    • Cells
    • Role
    • Structures
    • Surface
    • Expression
    • Metastasis

Connections between topic areas Semantic bridges

For Selectin, one of the stronger structural bridges in this analysis connects Selectin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SelectinOverview · splits 33 ⟂ 10
SelectinFunction · splits 34 ⟂ 9
SelectinTypes · splits 35 ⟂ 8
SelectinResearch · splits 37 ⟂ 6
SelectinRole in cancer · splits 40 ⟂ 3

Map overview Semantic statistics

Selectin

Nodes43
Edges42
Triples71
Avg. degree1.95
Density0.046512
Components1

Source & methodology

TTTA analyzes the structure around Selectin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Research, Function & Types, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Selectin · EN edition · Analysis: TopicsToTalkAbout

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