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Selectin

The selectins (cluster of differentiation 62 or CD62) are a family of cell adhesion molecules (or CAMs). All selectins are single-chain transmembrane glycoproteins that share similar properties to C-type lectins due to a related amino terminus and calcium-dependent binding. Selectins bind to sugar moieties and so are considered to be a type of lectin…

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AlphaFold
IPR002396
Available protein structures:
IPR002396
InterPro
IPR002396
Membranome
12
PDB
IPR002396
Symbol
Selectin

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Etymology

Function

Bonding mechanisms

Role in cancer

Research

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Map overview Semantic statistics

Selectin

Nodes43
Edges42
Triples71
Avg. degree1.95
Density0.046512
Components1

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Selectin

Top relations

related to Organ selectivity · 9
Selectin → ICAM, Ig-CAM, In, Metastatic, Moreover, Several, The, This, Typically
related to Function · 8
Selectin → Cytokines, During, E-selectin, P-selectin, Selectins, Stimuli, TNF-alpha, Weible-Palade
related to Structure · 7
Selectin → All, EGF, N-terminal, P-selectin, The, Though, TM
related to Role in cancer · 6
Selectin → E-selectin, In, It, L-selectin, P-selectin, Tumor
related to Bonding mechanisms · 5
Selectin → In, Lewis, PSGL-1, Selectins, Shear
related to Research · 5
Selectin → E-selectins, Osteoblasts, Researchers, Selectins, Thus
related to External links · 4
Selectin → P-selectin, Research Archived, Sackstein Lab, Wayback MachineComputer-generated
related to Types · 4
Selectin → E-selectin, L-selectin, P-selectin, There
is a · 2
Selectin → sialylated Lewis X antigen, smallest of the vascular selectins
AlphaFold · 1
Selectin → IPR002396

Important terminology Word statistics

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Important terminology

selectins cells p-selectin endothelial e-selectin cancer binding bind cell expressed adhesion lectin metastasis ligands may organ expression transmembrane similar structure

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SelectinAlphaFoldIPR0023961.00infobox
SelectinAvailable protein structures:IPR0023961.00infobox
SelectinInterProIPR0023961.00infobox
SelectinMembranome121.00infobox
SelectinPDBIPR0023961.00infobox
SelectinSymbolSelectin1.00infobox
Selectinis asmallest of the vascular selectins0.90text
Selectinis asialylated Lewis X antigen0.90text
histamineinstance ofStimuli0.80text
thrombin cause endothelial cells to mobilize immediate release of preformed P-selectin from Weible-Palade bodies inside the cellinstance ofStimuli0.80text
TNF-alpha stimulate transcriptioninstance ofCytokines0.80text
translation of E-selectininstance ofCytokines0.80text

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    Min side: 3
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