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Second messenger system

Second messengers are intracellular signaling molecules released by the target cell in response to exposure to extracellular signaling molecules—the first messengers. (Intercellular signals, a non-local form of cell signaling, encompassing both first messengers and second messengers, are classified as autocrine, juxtacrine, paracrine, and endocrine…

Types of second messenger molecules, Common mechanisms of second messenger systems & Overview

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Types of second messenger molecules

HydrophobicDiacylglycerolPhosphatidylinositolsPlasma membraneIntermembrane space
15 related topics

Common mechanisms of second messenger systems

PhosphoinositolArachidonic acidLigandCell surface receptorG protein-coupled receptors
13 related topics

Overview

Intracellular signalingCell signalingAutocrineJuxtacrineParacrine
39 related topics

Second messengers in the phosphoinositol signaling pathway

Guanine nucleotide exchange factors
1 related topics

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Overview

Types of second messenger molecules

Common mechanisms of second messenger systems

Second messengers in the phosphoinositol signaling pathway

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Second messenger system

Nodes73
Edges72
Triples27
Avg. degree1.97
Density0.027397
Components1

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Important terminology

messengers second messenger molecules cell signal first signaling needed citation epinephrine diacylglycerol receptor ca2 extracellular may g-protein calcium membrane binds

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
proliferationinstance ofSecond messengers trigger physiological changes at cellular level0.80text
differentiationinstance ofSecond messengers trigger physiological changes at cellular level0.80text
migrationinstance ofSecond messengers trigger physiological changes at cellular level0.80text
survivalinstance ofSecond messengers trigger physiological changes at cellular level0.80text
apoptosisinstance ofSecond messengers trigger physiological changes at cellular level0.80text
depolarization.They are one of the triggers of intracellular signal transduction cascades.Examples of second messenger molecules include cyclic AMPinstance ofSecond messengers trigger physiological changes at cellular level0.80text
cyclic GMPinstance ofSecond messengers trigger physiological changes at cellular level0.80text
inositol triphosphateinstance ofSecond messengers trigger physiological changes at cellular level0.80text
diacylglycerolinstance ofSecond messengers trigger physiological changes at cellular level0.80text
and calciuminstance ofSecond messengers trigger physiological changes at cellular level0.80text
Mycinstance ofcascade to amplify the allosteric activation of proliferative transcription factors0.80text
CREB.Earl Wilbur Sutherland Jr.instance ofcascade to amplify the allosteric activation of proliferative transcription factors0.80text

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