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S100 calcium-binding protein B (S100B) is a protein of the S100 protein family.
The analysis highlights Applications, Interactions and Clinical significance as prominent areas in the source structure around S100B.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around S100B shows recurring relationship patterns in the source. For example, S100B → astrocyte differentiation, axonogenesis, calcium ion binding, calcium-dependent protein binding, cell population proliferation, cellular response to hypoxia, central nervous system development, cytoplasm, extracellular region, extracellular space, identical protein binding, innate immune response, learning or memory, long-term potentiation, memory, metal ion binding, negative regulation of skeletal muscle cell differentiation, nucleus, perinuclear region of cytoplasm, positive regulation of apoptotic process Another extracted example is S100B → anterior horn of spinal cord, C1 segment, cerebellar vermis, deep cerebellar nuclei, facial motor nucleus, inferior ganglion of vagus nerve, internal globus pallidus, lobe of cerebellum, medulla oblongata, olfactory bulb, optic nerve, pars reticulata, pontine nuclei, stria vascularis, substantia nigra, subthalamic nucleus, superior vestibular nucleus, trigeminal ganglion, utricle, vestibular membrane of cochlear duct. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
levels s100 bp human protein chromosome gene chr band serum cns 21 brain injury cells clinical regulation location function cytoplasm
TTTA extracted 125 structured relationships around S100B. Examples in this analysis include S100B → Aliases → S100B, NEF, S100, S100-B, S100beta, S100 calcium binding protein B and S100B → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MQ1, 1UWO, 2H61, 2M49, 2PRU, 3CZT, 3D0Y, 3D10, 3HCM, 4XYN, 5CSJ, 5CSF, 5CSN, 5CSI. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| S100B | Aliases | S100B, NEF, S100, S100-B, S100beta, S100 calcium binding protein B | 1.00 | infobox |
| S100B | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MQ1, 1UWO, 2H61, 2M49, 2PRU, 3CZT, 3D0Y, 3D10, 3HCM, 4XYN, 5CSJ, 5CSF, 5CSN, 5CSI | 1.00 | infobox |
| S100B | Band | 21q22.3 | 1.00 | infobox |
| S100B | Band | 10 C1|10 38.76 cM | 1.00 | infobox |
| S100B | Bgee | C1 segment | 1.00 | infobox |
| S100B | Bgee | inferior ganglion of vagus nerve | 1.00 | infobox |
| S100B | Bgee | olfactory bulb | 1.00 | infobox |
| S100B | Bgee | subthalamic nucleus | 1.00 | infobox |
| S100B | Bgee | trigeminal ganglion | 1.00 | infobox |
| S100B | Bgee | internal globus pallidus | 1.00 | infobox |
| S100B | Bgee | medulla oblongata | 1.00 | infobox |
| S100B | Bgee | superior vestibular nucleus | 1.00 | infobox |
| S100B | Bgee | substantia nigra | 1.00 | infobox |
| S100B | Bgee | pars reticulata | 1.00 | infobox |
| S100B | Bgee | vestibular membrane of cochlear duct | 1.00 | infobox |
| S100B | Bgee | lobe of cerebellum | 1.00 | infobox |
| S100B | Bgee | anterior horn of spinal cord | 1.00 | infobox |
| S100B | Bgee | cerebellar vermis | 1.00 | infobox |
| S100B | Bgee | deep cerebellar nuclei | 1.00 | infobox |
| S100B | Bgee | stria vascularis | 1.00 | infobox |
| S100B | Bgee | pontine nuclei | 1.00 | infobox |
| S100B | Bgee | facial motor nucleus | 1.00 | infobox |
| S100B | Bgee | optic nerve | 1.00 | infobox |
| S100B | Bgee | utricle | 1.00 | infobox |
| S100B | BioGPS | More reference expression data | 1.00 | infobox |
| S100B | Chr. | Chromosome 21 (human) | 1.00 | infobox |
| S100B | Chr. | Chromosome 10 (mouse) | 1.00 | infobox |
| S100B | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| S100B | End | 46,605,208 bp | 1.00 | infobox |
| S100B | End | 76,096,993 bp | 1.00 | infobox |
The concept neighborhoods around S100B bring nearby vocabulary together. In this analysis, examples include Serum, Injury and Changes. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For S100B, one of the stronger structural bridges in this analysis connects S100B with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around S100B to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Interactions & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — S100B · EN edition · Analysis: TopicsToTalkAbout
