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S100B

S100 calcium-binding protein B (S100B) is a protein of the S100 protein family.

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Aliases
S100B, NEF, S100, S100-B, S100beta, S100 calcium binding protein B
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MQ1, 1UWO, 2H61, 2M49, 2PRU, 3CZT, 3D0Y, 3D10, 3HCM, 4XYN, 5CSJ, 5CSF, 5CSN, 5CSI
Band
21q22.3 · 10 C1|10 38.76 cM
Bgee
C1 segment · inferior ganglion of vagus nerve · olfactory bulb · subthalamic nucleus · trigeminal ganglion
BioGPS
More reference expression data
Chr.
Chromosome 21 (human) · Chromosome 10 (mouse)

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Overview

Function

Clinical significance

Diagnostic use

Interactions

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Map overview Semantic statistics

S100B

Nodes46
Edges45
Triples136
Avg. degree1.96
Density0.043478
Components1

How this topic connects Entity context

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S100B

Top relations

Gene ontology · 37
S100B → astrocyte differentiation, axonogenesis, calcium ion binding, calcium-dependent protein binding, cell population proliferation, cellular response to hypoxia, central nervous system development, cytoplasm, extracellular region, extracellular space, identical protein binding, innate immune response, learning or memory, long-term potentiation, memory, metal ion binding, negative regulation of skeletal muscle cell differentiation, nucleus, perinuclear region of cytoplasm, positive regulation of apoptotic process
Bgee · 20
S100B → anterior horn of spinal cord, C1 segment, cerebellar vermis, deep cerebellar nuclei, facial motor nucleus, inferior ganglion of vagus nerve, internal globus pallidus, lobe of cerebellum, medulla oblongata, olfactory bulb, optic nerve, pars reticulata, pontine nuclei, stria vascularis, substantia nigra, subthalamic nucleus, superior vestibular nucleus, trigeminal ganglion, utricle, vestibular membrane of cochlear duct
RNA expression pattern · 20
S100B → anterior horn of spinal cord, C1 segment, cerebellar vermis, deep cerebellar nuclei, facial motor nucleus, inferior ganglion of vagus nerve, internal globus pallidus, lobe of cerebellum, medulla oblongata, olfactory bulb, optic nerve, pars reticulata, pontine nuclei, stria vascularis, substantia nigra, subthalamic nucleus, superior vestibular nucleus, trigeminal ganglion, utricle, vestibular membrane of cochlear duct
related to Diagnostic use · 14
S100B → An, BBB, CNS, CSF, CT, Elevated S100B, However, In, Its, Normal S100B, Over, Serum, The, Thus
related to Interactions · 9
S100B → AHNAK, IMPA1, IQGAP1, MAPT, PGM1, S100A1, S100A11, S100A6, VAV1
related to Function · 7
S100B → Ca2, CNS, In, It, NG2-expressing, PKC-mediated, This
related to Clinical significance · 4
S100B → Alzheimer's, Chromosomal, Down, It
Band · 2
S100B → 10 C1|10 38.76 cM, 21q22.3
Chr. · 2
S100B → Chromosome 10 (mouse), Chromosome 21 (human)
End · 2
S100B → 46,605,208 bp, 76,096,993 bp

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Important terminology

levels s100 bp human protein chromosome gene chr band serum cns 21 brain injury cells clinical regulation location function cytoplasm

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
S100BAliasesS100B, NEF, S100, S100-B, S100beta, S100 calcium binding protein B1.00infobox
S100BAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MQ1, 1UWO, 2H61, 2M49, 2PRU, 3CZT, 3D0Y, 3D10, 3HCM, 4XYN, 5CSJ, 5CSF, 5CSN, 5CSI1.00infobox
S100BBand21q22.31.00infobox
S100BBand10 C1|10 38.76 cM1.00infobox
S100BBgeeC1 segment1.00infobox
S100BBgeeinferior ganglion of vagus nerve1.00infobox
S100BBgeeolfactory bulb1.00infobox
S100BBgeesubthalamic nucleus1.00infobox
S100BBgeetrigeminal ganglion1.00infobox
S100BBgeeinternal globus pallidus1.00infobox
S100BBgeemedulla oblongata1.00infobox
S100BBgeesuperior vestibular nucleus1.00infobox
S100BBgeesubstantia nigra1.00infobox
S100BBgeepars reticulata1.00infobox
S100BBgeevestibular membrane of cochlear duct1.00infobox
S100BBgeelobe of cerebellum1.00infobox
S100BBgeeanterior horn of spinal cord1.00infobox
S100BBgeecerebellar vermis1.00infobox
S100BBgeedeep cerebellar nuclei1.00infobox
S100BBgeestria vascularis1.00infobox
S100BBgeepontine nuclei1.00infobox
S100BBgeefacial motor nucleus1.00infobox
S100BBgeeoptic nerve1.00infobox
S100BBgeeutricle1.00infobox
S100BBioGPSMore reference expression data1.00infobox
S100BChr.Chromosome 21 (human)1.00infobox
S100BChr.Chromosome 10 (mouse)1.00infobox
S100BDatabasesNCBI: entry; OMA: entry1.00infobox
S100BEnd46,605,208 bp1.00infobox
S100BEnd76,096,993 bp1.00infobox

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