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Explore the main themes, entities and connections around Rapastinel. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Preclinical research

Enhance memory and learning Learning-impaired Rat models Schaffer collateral CA1

15 related topics

Clinical development

Fast Track designation Phase II Proof of concept HAM-D Breakthrough Therapy

9 related topics

Overview

INN Antidepressant Allergan Naurex Adjunctive therapy

18 related topics

History

Structural modification B6B21 Monoclonal antibody

3 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol): Interactive image
ATC code: None
CAS Number: 117928-94-6 Y
ChemSpider: 25069944
CompTox Dashboard (EPA): DTXSID501030481
Drug class: Selective NMDA receptor modulator

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

INN International Nonproprietary Name
Antidepressant
Allergan
Naurex
Adjunctive therapy
Treatment-resistant depression
Centrally active Central nervous system
Intravenously Intravenous
Administered Drug administration
Orally active Oral administration
Amidated Amide
Tetrapeptide
Selective Binding selectivity
Modulator Receptor modulator
NMDA receptor
Cognitive enhancer
Signal transduction
Synaptic plasticity

Clinical development

Fast Track designation FDA Fast Track Development Program
Phase II Phases of clinical research
Proof of concept
HAM-D Hamilton Rating Scale for Depression
Breakthrough Therapy
Apimostinel
Analog Structural analog
Potency Potency (pharmacology)
Zelquistinel AGN-241751

Pharmacology

Preclinical research

History

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Rapastinel

Nodes56

Edges55

Triples56

Avg. degree1.96

Density0.035714

Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Rapastinel

Top relations

related to Clinical development · 17

Rapastinel → AGN-241751, Allergan, As, Breakthrough Therapy, Early, Fast Track, FDA, GATE-202, GATE-251, HAM-D, II, III, July, Naurex, NRX-1074, On January, On March

related to Preclinical research · 9

Rapastinel → CA1, CA3, In, It, Mongolian Gerbils, Neuroprotective, NMDA, NR1, Schaffer

related to External links · 7

Rapastinel → AdisInsightRapastinel, Allergan, GLYX-13, Inc, Naurex, Rapastinel Receives FDA Breakthrough, Therapy Designation

related to history · 4

Rapastinel → B6B21, Joseph Moskal, Naurex, NMDA

related to Pharmacology · 4

Rapastinel → At, NMDA, NMDAR-mediated, Positive

3D model (JSmol) · 1

Rapastinel → Interactive image

ATC code · 1

Rapastinel → None

CAS Number · 1

Rapastinel → 117928-94-6 Y

ChemSpider · 1

Rapastinel → 25069944

CompTox Dashboard (EPA) · 1

Rapastinel → DTXSID501030481

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

nmda receptor antidepressant development allergan naurex therapy novel glyx-13 drug effects adjunctive selective modulator clinical also name code fda designation

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Rapastinel	3D model (JSmol)	Interactive image	1.00	infobox
Rapastinel	ATC code	None	1.00	infobox
Rapastinel	CAS Number	117928-94-6 Y	1.00	infobox
Rapastinel	ChemSpider	25069944	1.00	infobox
Rapastinel	CompTox Dashboard (EPA)	DTXSID501030481	1.00	infobox
Rapastinel	Drug class	Selective NMDA receptor modulator	1.00	infobox
Rapastinel	Formula	C18H31N5O6	1.00	infobox
Rapastinel	Legal status	US: Investigational New Drug	1.00	infobox
Rapastinel	Molar mass	413.475 g·mol−1	1.00	infobox
Rapastinel	Other names	GLYX-13; BV-102	1.00	infobox
Rapastinel	PubChem CID	14539800	1.00	infobox
Rapastinel	Routes of administration	Intravenous	1.00	infobox
Rapastinel	UNII	6A1X56B95E	1.00	infobox

Related concept clusters Concept neighborhoods

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Connections between topic areas Semantic bridges

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Min side: 3