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GRHPR: Overview, Related Topics & Entities

Glyoxylate reductase/hydroxypyruvate reductase is an enzyme that in humans is encoded by the GRHPR gene.

Language: English [EN]
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GRHPR topic overview

The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around GRHPR.

Related topics
6
Source areas
1
Connected nodes
7
Extracted relationships
84
Concept neighborhoods
8
Bridge connections
7

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.1.1.79
1.1.1.81
Aliases
GRHPR, GLXR, GLYD, PH2, glyoxylate reductase/hydroxypyruvate reductase, glyoxylate and hydroxypyruvate reductase
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GCG, 2H1S, 2Q50, 2WWR
Band
9p13.2 · 4|4 B1
Bgee
right lobe of liver · right adrenal gland · left adrenal gland · right adrenal cortex · left adrenal cortex

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GRHPR connects Entity context

The extracted context around GRHPR shows recurring relationship patterns in the source. For example, GRHPR → carboxylic acid binding, cellular nitrogen compound metabolic process, cytoplasm, cytosol, dicarboxylic acid metabolic process, excretion, extracellular exosome, glycerate dehydrogenase activity, glyoxylate metabolic process, glyoxylate reductase (NADP+) activity, hydroxypyruvate reductase activity, metabolism, NAD binding, NADP binding, NADPH binding, oxidoreductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, peroxisomal matrix, protein complex oligomerization, protein homodimerization activity Another extracted example is GRHPR → adrenal gland, apex of heart, brown adipose tissue, C1 segment, cumulus cell, epithelium of stomach, human kidney, Ileal epithelium, left adrenal cortex, left adrenal gland, left lobe of liver, muscle of thigh, proximal tubule, right adrenal cortex, right adrenal gland, right kidney, right lobe of liver, tendon of biceps brachii, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

GRHPR

Top relations

Gene ontology · 20
GRHPR → carboxylic acid binding, cellular nitrogen compound metabolic process, cytoplasm, cytosol, dicarboxylic acid metabolic process, excretion, extracellular exosome, glycerate dehydrogenase activity, glyoxylate metabolic process, glyoxylate reductase (NADP+) activity, hydroxypyruvate reductase activity, metabolism, NAD binding, NADP binding, NADPH binding, oxidoreductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, peroxisomal matrix, protein complex oligomerization, protein homodimerization activity
Bgee · 19
GRHPR → adrenal gland, apex of heart, brown adipose tissue, C1 segment, cumulus cell, epithelium of stomach, human kidney, Ileal epithelium, left adrenal cortex, left adrenal gland, left lobe of liver, muscle of thigh, proximal tubule, right adrenal cortex, right adrenal gland, right kidney, right lobe of liver, tendon of biceps brachii, yolk sac
RNA expression pattern · 19
GRHPR → adrenal gland, apex of heart, brown adipose tissue, C1 segment, cumulus cell, epithelium of stomach, human kidney, Ileal epithelium, left adrenal cortex, left adrenal gland, left lobe of liver, muscle of thigh, proximal tubule, right adrenal cortex, right adrenal gland, right kidney, right lobe of liver, tendon of biceps brachii, yolk sac
Band · 2
GRHPR → 4|4 B1, 9p13.2
Chr. · 2
GRHPR → Chromosome 4 (mouse), Chromosome 9 (human)
End · 2
GRHPR → 37,436,990 bp, 44,990,734 bp
1.1.1.79 · 1
GRHPR → ↗
1.1.1.81 · 1
GRHPR → ↗
Aliases · 1
GRHPR → GRHPR, GLXR, GLYD, PH2, glyoxylate reductase/hydroxypyruvate reductase, glyoxylate and hydroxypyruvate reductase
Available structures · 1
GRHPR → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GCG, 2H1S, 2Q50, 2WWR

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp enzyme chr human band glyoxylate reductase hydroxypyruvate chromosome location 990 metabolism mouse dehydrogenase tissue expression hyperoxaluria external type

GRHPR relationships Subject–Predicate–Object triples

TTTA extracted 84 structured relationships around GRHPR. Examples in this analysis include GRHPR → 1.1.1.79 → ↗ and GRHPR → Aliases → GRHPR, GLXR, GLYD, PH2, glyoxylate reductase/hydroxypyruvate reductase, glyoxylate and hydroxypyruvate reductase. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GRHPR1.1.1.791.00infobox
GRHPR1.1.1.811.00infobox
GRHPRAliasesGRHPR, GLXR, GLYD, PH2, glyoxylate reductase/hydroxypyruvate reductase, glyoxylate and hydroxypyruvate reductase1.00infobox
GRHPRAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GCG, 2H1S, 2Q50, 2WWR1.00infobox
GRHPRBand9p13.21.00infobox
GRHPRBand4|4 B11.00infobox
GRHPRBgeeright lobe of liver1.00infobox
GRHPRBgeeright adrenal gland1.00infobox
GRHPRBgeeleft adrenal gland1.00infobox
GRHPRBgeeright adrenal cortex1.00infobox
GRHPRBgeeleft adrenal cortex1.00infobox
GRHPRBgeetendon of biceps brachii1.00infobox
GRHPRBgeehuman kidney1.00infobox
GRHPRBgeemuscle of thigh1.00infobox
GRHPRBgeeapex of heart1.00infobox
GRHPRBgeeC1 segment1.00infobox
GRHPRBgeeleft lobe of liver1.00infobox
GRHPRBgeeright kidney1.00infobox
GRHPRBgeeproximal tubule1.00infobox
GRHPRBgeeIleal epithelium1.00infobox
GRHPRBgeeadrenal gland1.00infobox
GRHPRBgeeyolk sac1.00infobox
GRHPRBgeecumulus cell1.00infobox
GRHPRBgeeepithelium of stomach1.00infobox
GRHPRBgeebrown adipose tissue1.00infobox
GRHPRBioGPSMore reference expression data1.00infobox
GRHPRChr.Chromosome 9 (human)1.00infobox
GRHPRChr.Chromosome 4 (mouse)1.00infobox
GRHPRDatabasesNCBI: entry; OMA: entry1.00infobox
GRHPREnd37,436,990 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GRHPR bring nearby vocabulary together. In this analysis, examples include Hydroxypyruvate, Reductase and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • enzyme
    • Glyoxylate
    • Hydroxypyruvate
    • Reductase
    • Gene
    • Grhpr
    • Activities
    • D-glycerate
    • Encoded
    • Encodes
    • Enzymatic
    • External
    • Humans
  • gene
    • Glyoxylate
    • Hydroxypyruvate
    • Reductase
    • Location
    • Chromosome
    • Grhpr
    • Human
    • Bp
    • Chr
    • Activity
    • Dehydrogenase
    • End
  • hydroxypyruvate reductase
    • Reductase
    • Grhpr
    • Activity
    • Dehydrogenase
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Activities
    • D-glycerate
  • glyoxylate reductase
    • Hydroxypyruvate
    • Reductase
    • Gene
    • Enzyme
    • Grhpr
    • Activity
    • Dehydrogenase
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
  • glycerate dehydrogenase
    • Activities
    • Encodes
    • Entry
    • Enzymatic
    • Glyoxylate
    • Hydroxypyruvate
    • Ncbi
    • Reductase
    • Activity
    • End
    • Expression
    • Gene
  • GRHPR
    • Hydroxypyruvate
    • Reductase
    • Activity
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Entry
    • External
    • Humans
  • grhpr
    • Hydroxypyruvate
    • Reductase
    • Activity
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Entry
    • External
    • Humans
  • hyperoxaluria
    • Type
    • Caused
    • Entry
    • Ii
    • Mutations
    • Ncbi
    • Activity
    • End
    • Metabolism
    • Mouse
    • Search
    • Tissue

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the GRHPR map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

GRHPR

Nodes8
Edges7
Triples84
Avg. degree1.75
Density0.25
Components1

Source & methodology

TTTA analyzes the structure around GRHPR to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GRHPR · EN edition · Analysis: TopicsToTalkAbout

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