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AGXT

Serine—pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene.

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2.6.1.44
2.6.1.51
Aliases
AGXT, AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6, alanine-glyoxylate aminotransferase, alanine--glyoxylate and serine--pyruvate aminotransferase, Ser-PyrAT
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H0C, 1J04, 2YOB, 3R9A, 4CBR, 4CBS, 4I8A, 4KXK, 4KYO
Band
2q37.3 · 1 D|1 47.0 cM
Bgee
right lobe of liver · buccal mucosa cell · cartilage tissue · human kidney · testicle

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AGXT

Nodes8
Edges7
Triples101
Avg. degree1.75
Density0.25
Components1

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AGXT

Top relations

Gene ontology · 30
AGXT → alanine-glyoxylate transaminase activity, amino acid binding, catalytic activity, cellular nitrogen compound metabolic process, cytosol, glycine biosynthetic process, by transamination of glyoxylate, glyoxylate catabolic process, glyoxylate metabolic process, identical protein binding, intracellular membrane-bounded organelle, L-alanine catabolic process, L-cysteine catabolic process, mitochondrial matrix, mitochondrion, Notch signaling pathway, oxalic acid secretion, peroxisomal matrix, peroxisome, protein binding, protein homodimerization activity
Bgee · 20
AGXT → buccal mucosa cell, CA3 field, cartilage tissue, cerebellar vermis, duodenum, embryo, gallbladder, gastrula, gonad, human kidney, Ileal epithelium, jejunum, kidney tubule, left lobe of liver, renal cortex, renal medulla, right lobe of liver, sexually immature organism, submandibular gland, testicle
RNA expression pattern · 20
AGXT → buccal mucosa cell, CA3 field, cartilage tissue, cerebellar vermis, duodenum, embryo, gallbladder, gastrula, gonad, human kidney, Ileal epithelium, jejunum, kidney tubule, left lobe of liver, renal cortex, renal medulla, right lobe of liver, sexually immature organism, submandibular gland, testicle
related to External links · 5
AGXT → AGT, GeneReviews/NIH/NCBI/UW, Human AGXT, Primary Hyperoxaluria Type, UCSC Genome Browser
Band · 2
AGXT → 1 D|1 47.0 cM, 2q37.3
Chr. · 2
AGXT → Chromosome 1 (mouse), Chromosome 2 (human)
End · 2
AGXT → 240,880,502 bp, 93,073,143 bp
2.6.1.44 · 1
AGXT → ↗
2.6.1.51 · 1
AGXT → ↗
Aliases · 1
AGXT → AGXT, AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6, alanine-glyoxylate aminotransferase, alanine--glyoxylate and serine--pyruvate aminotransferase, Ser-PyrAT

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Important terminology

gene human bp chr band location chromosome encoded enzyme glyoxylate mouse ucsc pyruvate aminotransferase expressed liver protein targeting hyperoxaluria external

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
AGXT2.6.1.441.00infobox
AGXT2.6.1.511.00infobox
AGXTAliasesAGXT, AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6, alanine-glyoxylate aminotransferase, alanine--glyoxylate and serine--pyruvate aminotransferase, Ser-PyrAT1.00infobox
AGXTAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H0C, 1J04, 2YOB, 3R9A, 4CBR, 4CBS, 4I8A, 4KXK, 4KYO1.00infobox
AGXTBand2q37.31.00infobox
AGXTBand1 D|1 47.0 cM1.00infobox
AGXTBgeeright lobe of liver1.00infobox
AGXTBgeebuccal mucosa cell1.00infobox
AGXTBgeecartilage tissue1.00infobox
AGXTBgeehuman kidney1.00infobox
AGXTBgeetesticle1.00infobox
AGXTBgeekidney tubule1.00infobox
AGXTBgeecerebellar vermis1.00infobox
AGXTBgeegonad1.00infobox
AGXTBgeerenal medulla1.00infobox
AGXTBgeerenal cortex1.00infobox
AGXTBgeeleft lobe of liver1.00infobox
AGXTBgeeembryo1.00infobox
AGXTBgeegallbladder1.00infobox
AGXTBgeesexually immature organism1.00infobox
AGXTBgeegastrula1.00infobox
AGXTBgeeduodenum1.00infobox
AGXTBgeejejunum1.00infobox
AGXTBgeeIleal epithelium1.00infobox
AGXTBgeeCA3 field1.00infobox
AGXTBgeesubmandibular gland1.00infobox
AGXTBioGPSMore reference expression data1.00infobox
AGXTChr.Chromosome 2 (human)1.00infobox
AGXTChr.Chromosome 1 (mouse)1.00infobox
AGXTDatabasesNCBI: entry; OMA: entry1.00infobox

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