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AGXT: Overview, Related Topics & Entities

Serine—pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene.

Language: English [EN]
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AGXT topic overview

The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around AGXT.

Related topics
6
Source areas
1
Connected nodes
7
Extracted relationships
101
Concept neighborhoods
8
Bridge connections
7

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.6.1.44
2.6.1.51
Aliases
AGXT, AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6, alanine-glyoxylate aminotransferase, alanine--glyoxylate and serine--pyruvate aminotransferase, Ser-PyrAT
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H0C, 1J04, 2YOB, 3R9A, 4CBR, 4CBS, 4I8A, 4KXK, 4KYO
Band
2q37.3 · 1 D|1 47.0 cM
Bgee
right lobe of liver · buccal mucosa cell · cartilage tissue · human kidney · testicle

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How AGXT connects Entity context

The extracted context around AGXT shows recurring relationship patterns in the source. For example, AGXT → alanine-glyoxylate transaminase activity, amino acid binding, catalytic activity, cellular nitrogen compound metabolic process, cytosol, glycine biosynthetic process, by transamination of glyoxylate, glyoxylate catabolic process, glyoxylate metabolic process, identical protein binding, intracellular membrane-bounded organelle, L-alanine catabolic process, L-cysteine catabolic process, mitochondrial matrix, mitochondrion, Notch signaling pathway, oxalic acid secretion, peroxisomal matrix, peroxisome, protein binding, protein homodimerization activity Another extracted example is AGXT → buccal mucosa cell, CA3 field, cartilage tissue, cerebellar vermis, duodenum, embryo, gallbladder, gastrula, gonad, human kidney, Ileal epithelium, jejunum, kidney tubule, left lobe of liver, renal cortex, renal medulla, right lobe of liver, sexually immature organism, submandibular gland, testicle. Use these groups to spot repeated connection types before inspecting the individual relationships.

AGXT

Top relations

Gene ontology · 30
AGXT → alanine-glyoxylate transaminase activity, amino acid binding, catalytic activity, cellular nitrogen compound metabolic process, cytosol, glycine biosynthetic process, by transamination of glyoxylate, glyoxylate catabolic process, glyoxylate metabolic process, identical protein binding, intracellular membrane-bounded organelle, L-alanine catabolic process, L-cysteine catabolic process, mitochondrial matrix, mitochondrion, Notch signaling pathway, oxalic acid secretion, peroxisomal matrix, peroxisome, protein binding, protein homodimerization activity
Bgee · 20
AGXT → buccal mucosa cell, CA3 field, cartilage tissue, cerebellar vermis, duodenum, embryo, gallbladder, gastrula, gonad, human kidney, Ileal epithelium, jejunum, kidney tubule, left lobe of liver, renal cortex, renal medulla, right lobe of liver, sexually immature organism, submandibular gland, testicle
RNA expression pattern · 20
AGXT → buccal mucosa cell, CA3 field, cartilage tissue, cerebellar vermis, duodenum, embryo, gallbladder, gastrula, gonad, human kidney, Ileal epithelium, jejunum, kidney tubule, left lobe of liver, renal cortex, renal medulla, right lobe of liver, sexually immature organism, submandibular gland, testicle
related to External links · 5
AGXT → AGT, GeneReviews/NIH/NCBI/UW, Human AGXT, Primary Hyperoxaluria Type, UCSC Genome Browser
Band · 2
AGXT → 1 D|1 47.0 cM, 2q37.3
Chr. · 2
AGXT → Chromosome 1 (mouse), Chromosome 2 (human)
End · 2
AGXT → 240,880,502 bp, 93,073,143 bp
2.6.1.44 · 1
AGXT → ↗
2.6.1.51 · 1
AGXT → ↗
Aliases · 1
AGXT → AGXT, AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6, alanine-glyoxylate aminotransferase, alanine--glyoxylate and serine--pyruvate aminotransferase, Ser-PyrAT

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene human bp chr band location chromosome encoded enzyme glyoxylate mouse ucsc pyruvate aminotransferase expressed liver protein targeting hyperoxaluria external

AGXT relationships Subject–Predicate–Object triples

TTTA extracted 101 structured relationships around AGXT. Examples in this analysis include AGXT → 2.6.1.44 → ↗ and AGXT → Aliases → AGXT, AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6, alanine-glyoxylate aminotransferase, alanine--glyoxylate and serine--pyruvate aminotransferase, Ser-PyrAT. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
AGXT2.6.1.441.00infobox
AGXT2.6.1.511.00infobox
AGXTAliasesAGXT, AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6, alanine-glyoxylate aminotransferase, alanine--glyoxylate and serine--pyruvate aminotransferase, Ser-PyrAT1.00infobox
AGXTAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H0C, 1J04, 2YOB, 3R9A, 4CBR, 4CBS, 4I8A, 4KXK, 4KYO1.00infobox
AGXTBand2q37.31.00infobox
AGXTBand1 D|1 47.0 cM1.00infobox
AGXTBgeeright lobe of liver1.00infobox
AGXTBgeebuccal mucosa cell1.00infobox
AGXTBgeecartilage tissue1.00infobox
AGXTBgeehuman kidney1.00infobox
AGXTBgeetesticle1.00infobox
AGXTBgeekidney tubule1.00infobox
AGXTBgeecerebellar vermis1.00infobox
AGXTBgeegonad1.00infobox
AGXTBgeerenal medulla1.00infobox
AGXTBgeerenal cortex1.00infobox
AGXTBgeeleft lobe of liver1.00infobox
AGXTBgeeembryo1.00infobox
AGXTBgeegallbladder1.00infobox
AGXTBgeesexually immature organism1.00infobox
AGXTBgeegastrula1.00infobox
AGXTBgeeduodenum1.00infobox
AGXTBgeejejunum1.00infobox
AGXTBgeeIleal epithelium1.00infobox
AGXTBgeeCA3 field1.00infobox
AGXTBgeesubmandibular gland1.00infobox
AGXTBioGPSMore reference expression data1.00infobox
AGXTChr.Chromosome 2 (human)1.00infobox
AGXTChr.Chromosome 1 (mouse)1.00infobox
AGXTDatabasesNCBI: entry; OMA: entry1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around AGXT bring nearby vocabulary together. In this analysis, examples include Location, Gene and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • AGXT
    • Location
    • Gene
    • Activity
    • Agt
    • Alanine-glyoxylate
    • Aminotransferase
    • Details
    • Enzyme
    • Genome
    • Human
    • Pyruvate
    • Search
  • agxt
    • Location
    • Gene
    • Activity
    • Agt
    • Alanine-glyoxylate
    • Aminotransferase
    • Details
    • Enzyme
    • Genome
    • Human
    • Pyruvate
    • Search
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Activity
    • Agt
    • Alanine-glyoxylate
    • Details
    • End
    • Expressed
    • Genome
  • glyoxylate
    • Liver
    • Protein
    • Entry
    • Ncbi
    • Peroxisomal
    • Peroxisomes
    • Activity
    • Agt
    • Alanine-glyoxylate
    • Details
    • End
    • Genome
  • hyperoxaluria
    • Primary
    • Targeting
    • Type
    • Entry
    • Ncbi
    • Peroxisomal
    • Activity
    • Agt
    • Alanine-glyoxylate
    • Details
    • End
    • Genome
  • type i primary
    • Hyperoxaluria
    • Targeting
    • Type
    • Entry
    • Ncbi
    • Peroxisomal
    • Activity
    • Agt
    • Alanine-glyoxylate
    • Details
    • End
    • Genome
  • enzyme
    • Agxt
    • External
    • Activity
    • Agt
    • Alanine-glyoxylate
    • Encoded
    • Pyruvate
    • Search
    • Gene
    • Chromosome
    • Location
    • Bp
  • peroxisomes
    • Protein

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the AGXT map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

AGXT

Nodes8
Edges7
Triples101
Avg. degree1.75
Density0.25
Components1

Source & methodology

TTTA analyzes the structure around AGXT to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — AGXT · EN edition · Analysis: TopicsToTalkAbout

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